\nHistoplasmosis is caused by Histoplasma capsulatum, a dimorphic fungus. It is distributed worldwide and predominant<\/span> in certain regions of North and Central America. Cutaneous<\/span> Manifestations are reported to occur in 10% to 25% of AIDS patients with disseminated<\/span> histoplasmosis<\/p>\n<\/span>\nHistology<\/span> histoplasmosis<\/span><\/h2>\nHistopathological examination of histoplasmosis reveals a dense dermal<\/span> infiltrate<\/span> low attenuated or uncomplicated epidermis<\/span> (Figure 1). In the higher power, the infiltrator is revealed to contain numerous plasma<\/span> cells, histiocytes<\/span> and lymphocytes<\/span> (Figure 2). Depending on the state of the host<\/span> and the stage of the injuries can be extensive granulomas<\/span>. Accompanying the infiltrate are numerous budding yeast forms, predominantly within histiocytes, and few organisms<\/span> residing extracellularly A clear space or artificial "halo" may be evident due to retraction of the basophilic<\/span> fungal cell cytoplasm<\/span> of the poorly stained cell wall (Figure 2, arrow). GMS confirms the presence of numerous fungal spores of 2\u20134 \u03bcm compatible with Histoplasma capsulatum (Figure 3).<\/p>\n\n<\/span>Histoplasmosis pathology<\/span><\/h5>\n<\/section>\n\n\n
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Figure 1<\/p>\n
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Figure 2<\/p>\n
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figure 3<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>Special spots for histoplasmosis.<\/span><\/h2>\nIn histoplasmosis, GMS and PAS are often required to help illustrate characteristic yeasts. This is especially useful in immunocompetent Hosts<\/span> with a quick inflammatory<\/span> reply.<\/p>\n\n
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<\/span>\nDifferential diagnosis<\/span> histoplasmosis pathology<\/span>
\n<\/span><\/h2>\nCryptococcus and blastomycosis: Mucicarmine positivity discriminates crytococcus from these other organisms. Blastomycosis is much bigger organism<\/span> and lacks the typical halo seen around forms of histoplasmosis. Blastomycosis generally causes rapid epidermal<\/span> reply.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"La histoplasmosis es causada por Histoplasma capsulatum, un hongo dimorfo. Se distribuye en todo el mundo y predominante en ciertas regiones de Am\u00e9rica del Norte y Central. Cut\u00e1neo Se informa…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-10284","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/10284","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=10284"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/10284\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=10284"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=10284"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=10284"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}