sex<\/span> and ethnic groups. However, it is more common among Asians, particularly young women. Women are affected twice as much as men.<\/p>\nIt has been increasingly associated with ketotic states associated with diabetes, fasting, and post-bariatric surgery.<\/p>\n
In some patients, prurigo pigmentosa has been associated with systemic<\/span> diseases like Sjogren syndrome<\/span> and eating disorders like anorexia nervosa. It has also been described in people with atopy<\/span>, as well as in pregnancy.<\/p>\n\n
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<\/span>What causes prurigo pigmentosa?<\/span><\/h2>\nThe exact role of carbohydrate exclusion and ketosis in the development of prurigo pigmentosa has not yet been elucidated.<\/p>\n
Several other mechanisms have been proposed for prurigo pigmentosa, including friction with clothing or contact. allergy<\/span> to trichlorphenol, chromium in acupuncture needles, chromium in detergent and nickel.<\/p>\n<\/span>How does prurigo pigmentosa appear?<\/span><\/h2>\nThe clinical characteristics of prurigo pigmentosa are:<\/p>\n
\n- A pruritus<\/span> rash (itching), which may come back<\/li>\n
- Swollen, raised red spots (papules<\/span>) that merge to form a lattice pattern (similar to a network)<\/li>\n
- \nSymmetrical<\/span> distribution<\/span> in the trunk that most often affects the upper back, sacrum (natal cleft<\/span>), abdomen and chest<\/li>\n
- Rare involvement of the face or extremities.<\/li>\n
- Save of mucous<\/span> membranes hair<\/span> and nail<\/span>\n<\/li>\n
- \nLattice<\/span> hyperpigmented<\/span> patches after resolution of the inflammatory phase of the rash.<\/li>\n<\/ul>\n
<\/span>\nHistopathology<\/span> of prurigo pigmentosa<\/span><\/h2>\nThere is a distinct histopathology in prurigo pigmentosa.<\/p>\n
\n- Early injury<\/span>: shallow perivascular<\/span> neutrophilic<\/span> infiltrate<\/span>and some necrotic<\/span> keratinocytes<\/span>\n<\/li>\n
- Injury developed: irregular lymphocytic<\/span> infiltrate and necrosis<\/span> of numerous keratinocytes<\/li>\n
- Late injury: lymphocytic infiltrate, scale<\/span>–Cortex<\/span>and melanophages<\/span>\n<\/li>\n<\/ul>\n
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<\/span>What is the treatment for prurigo pigmentosa?<\/span><\/h2>\nAdding carbohydrates to the diet may be beneficial if the patient is on a ketogenic diet or has undergone prolonged fasting or stomach surgery.<\/p>\n
Dapsone and tetracycline antibiotics are effective in treating prurigo pigmentosa during the inflammatory phase of the disease. These treatments are believed to work by interfering with movement and the function of neutrophils<\/span><\/span>. Macrolide antibiotics such as erythromycin have recently been shown to be useful as well. It is not clear if the antibacterial action of antibiotics is relevant.<\/p>\nCurrent<\/span> and systemic corticosteroids are not effective for prurigo pigmentosa.<\/p>\nTo date, there are no effective treatments for hyperpigmentation that develops in the later stages of the disease. Over time it fades away.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"
Que es prurigo pigmentosa? Prurigo pigmentosa es un raro inflamatorio condici\u00f3n de la piel asociada con cetosis. Se caracteriza por un recurrente que produce picor erupci\u00f3n con netlike hiperpigmentaci\u00f3n. Prurigo…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-16556","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16556","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=16556"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16556\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=16556"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=16556"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=16556"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}