<\/span><\/h2>\nThe scanning power of lichen sclerosus reveals a lichenoid<\/span> inflammatory<\/span> pattern in early stage lesions or superficial sclerosing process in late stage lesions (Figures 1 and 2). the epidermis<\/span> shows hyperkeratosis<\/span>, significant weight loss with loss of normal challenge<\/span> crest and plugging pattern follicular<\/span> infundibulae (Figure 3). A atrophic<\/span> the epidermis is not a requirement since some cases particularly in vulva<\/span> can show significant epidermal<\/span> hyperplasia<\/span>. Vacuolar<\/span> degeneration of the basal<\/span> cap<\/span> It can be seen, although typically mild, especially in late stage injuries. Cleft<\/span> may be evident between the epidermis and dermis<\/span> as a result of this degeneration of the basal layer and the underlying dermal<\/span> Changes The dominant feature is the wide condensation of the dermis. collagen<\/span>. These changes are typically superficial, whereas in early lesions they may show marked overlying papillary dermal edema<\/span>. When it extends into the deep dermis, discrimination of scleroderma<\/span> It can become difficult. The inflammatory infiltrate<\/span> evolves from a dense lichenoid lymphocytic<\/span> infiltrate a shallow scarce interstitial<\/span> infiltrate the late stage of the disease. Scattered plasma<\/span> cells, histiocytes<\/span> and mast cells<\/span> can be seen (Figure 4).<\/p>\n\n<\/span>Lichen sclerosus pathology<\/span><\/h5>\n<\/section>\n\n\n
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Figure 1<\/p>\n
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Figure 2<\/p>\n
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figure 3<\/p>\n
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Figure 4<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>\nDifferential diagnosis<\/span> lichen sclerosus pathology<\/span>
\n<\/span><\/h2>\nScleroderma: In this condition, the overlying epidermis and superficial dermis are preserved. Inflammatory infiltrate is typically sparse and deep attached<\/span> and vascular<\/span> Structures Overlap can occur where deep and superficial changes coexist.<\/p>\nLichen planus: the presence of a well-formed granular layer<\/span> and numerous cytoid bodies, and a lack of thickening of the basement or epidermal membrane atrophy<\/span> favor lichen planus over lichen sclerosus.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"Histolog\u00eda de liquen escleroso El poder de escaneo del liquen escleroso revela un liquenoide inflamatorio patr\u00f3n en lesiones en etapa temprana o un proceso esclerosante superficial en lesiones en etapa…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-16639","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16639","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=16639"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16639\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=16639"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=16639"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=16639"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}