<\/span><\/h2>\nLichenoid<\/span> drug reactions are induced by one drug or another exogenous<\/span> source that can mimic other lichenoids skin disease<\/span> clinically and histologically<\/span>.<\/p>\n<\/span>\nHistology<\/span> of the lichenoid drug eruption<\/span>
\n<\/span><\/h2>\nIn reactions to lichenoid medications, the pathology<\/span> it is almost identical to lichen planus. There is a dense band lymphocytic<\/span> infiltrate<\/span> in dermis<\/span> obscuring the dermoepidermal junction, cytoplasmic vacuolization of basal<\/span> keratinocytes<\/span> and apoptotic<\/span> keratinocytes that degenerate into colloid bodies (Figures 1,2). Furthermore, there are generally eosinophils<\/span> in the infiltrate (best seen in figure 3).<\/p>\n\n<\/span>Lichenoid drug rash pathology<\/span><\/h5>\n<\/section>\n\n\n
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Figure 1<\/p>\n
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Figure 2<\/p>\n
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figure 3<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>Special studies for lichenoid drug eruption.<\/span><\/h2>\nGenerally none is needed.<\/p>\n
<\/span>\nDifferential diagnosis<\/span> for lichenoid drug rash<\/span><\/h2>\nOther diagnoses to consider include any lichenoid skin disease<\/span>. The key differential is lichen planus. Clinical correlation can be very helpful. Key Histological Features Observed in the Lichenoid Drug rashes<\/span>, which are not common in idiopathic<\/span> Lichen planus, includes the presence of eosinophils and the presence of prominent parakeratosis<\/span>.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"Introducci\u00f3n Liquenoide las reacciones a medicamentos son inducidas por un medicamento u otro ex\u00f3geno fuente que puede imitar a otros liquenoides dermatosis cl\u00ednicamente y histol\u00f3gicamente. Histolog\u00eda de la droga liquenoide…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-16649","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16649","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=16649"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16649\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=16649"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=16649"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=16649"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}