\nLyme disease is a systemic<\/span> infection<\/span> caused by spirochete Borrelia burgdorferi. Chronic atrophic acrodermatitis is late cutaneous<\/span> form of the disease<\/p>\n<\/span>\nHistology<\/span> Lyme disease<\/span><\/h2>\nBiopsy<\/span> of erythema<\/span> Chronum migrans reveals a shallow and deep scarce infiltrate<\/span> under an not involved epidermis<\/span> (Figure 1). Sometimes there epidermal<\/span> me dermal<\/span> necrosis<\/span>. High power examination reveals that the infiltrate is primarily lymphocytic<\/span> (Figure 2). Often there is little eosinophils<\/span>, mixed plasma<\/span> cells and mast cells<\/span>.<\/p>\nChronic atrophic acrodermatitis lesions can show similar behavior. histopathology<\/span> but the infiltrate is denser (figure 3). The infiltrator consists of lymphocytes<\/span> and there are often numerous plasma cells (Figure 4) mixed with mast cells. There may be impressive superficial sclerosis<\/span> and fibroplasia<\/span>.<\/p>\n\n<\/span>Lyme disease pathology<\/span><\/h5>\n<\/section>\n\n\n
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Figure 1<\/p>\n
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Figure 2<\/p>\n
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figure 3<\/p>\n
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Figure 4<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>Special studies for Lyme disease.<\/span><\/h2>\nBorrelia spirochetes can be identified with silver spots and immunohistochemical methods in some cases. Many cases will be negative with these methods. Polymerase chain reaction<\/span> (PCR<\/span>) can also be used.<\/p>\n\n
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<\/span>\nDifferential diagnosis<\/span> Lyme disease pathology<\/span>
\n<\/span><\/h2>\nInsect sting reaction: Chronic migratory erythema lesions can be nonspecific and accurately mimic an insect sting reaction. This is particularly problematic when silver spots and immunohistochemical studies are negative. Clinical correlation, PCR studies, and serological correlation may be required.<\/p>\n
Sclerosing Disorders: Chronic atrophic acrodermatitis can cause a sclerosing reaction to closely simulate lichen sclerosus or eosinophilic<\/span> fasciitis<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"La enfermedad de Lyme es un sist\u00e9mico infecci\u00f3n causada por la espiroqueta Borrelia burgdorferi. La acrodermatitis cr\u00f3nica atr\u00f3fica es tard\u00eda cut\u00e1neo forma de la enfermedad Histolog\u00eda de la enfermedad de…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-16682","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16682","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=16682"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16682\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=16682"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=16682"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=16682"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}