\nLymphomatoid<\/span> papulosis is one of two primary<\/span> cutaneous<\/span> CD30 positive cutaneous lymphomas, according to the WHO \/ EORTC classification.<\/p>\n<\/span>\nHistology<\/span> lymphomatoid papulosis<\/span><\/h2>\nScanning power of pathology<\/span> of lymphomatoid papulosis reveals a wedge shape inflammatory<\/span> infiltrate<\/span> stretching deep dermis<\/span> or superficial subcutaneous<\/span> tissue (Figures 1 and 2). Please note that it is made of prominent telangiectatic vessels and extravasation<\/span> of erythrocytes<\/span> in the case illustrated here (Figures 3 and 4). the lymphocytic<\/span> the population is made up of a series of large CD30-positives lymphocytes<\/span> (Figure 5). The mixture of cells forms a spectrum.<\/p>\nType A: scattered or grouped<\/span> large positive CD30 lymphocytes (Figure 6) in a context of eosinophils<\/span> and neutrophils<\/span><\/span>.<\/p>\nType B: A population of small lymphocytes can be seen with epidermotropism<\/span>. This type may resemble mycosis fungoides.<\/p>\nType C: large leaves anaplastic<\/span> cells with only a few mixed inflammatory cells that resemble anaplastic large cells lymphoma<\/span>.<\/p>\nType D: marked epidermotropism is observed histologically<\/span> indistinguishable from CD8 + primary aggressive cutaneous epidermotropic cytotoxic<\/span> T cell<\/span> lymphoma<\/p>\n\n<\/span>Pathology of lymphomatoid papulosis.<\/span><\/h5>\n<\/section>\n\n\n
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Figure 1<\/p>\n
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Figure 2<\/p>\n
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figure 3<\/p>\n
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Figure 4<\/p>\n
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Figure 5<\/p>\n
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Figure 6<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>Special spots in lymphomatoid papulosis.<\/span><\/h2>\nA panel of immunoperoxidase markers is used, the key finding is CD30 positivity in types A and C. Typically tumor<\/span> cells are CD4 +, but CD8 + and CD56 + variants have been described. TIA-1, perforin, and granzyme-B are expressed while ALK-1 is negative.<\/p>\nThe expression of fascinates may indicate an increased risk of secondary malignancies.<\/p>\n
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<\/span>\nDifferential diagnosis<\/span> lymphomatoid papulosis<\/span><\/h2>\nPrimary cutaneous anaplastic cutaneous lymphoma: This tumor presents clinically in differential form as a large solitary ulcerated tumor. Strictly by definition, the> 75% of tumor cells must stain CD30 positive. A great nodular<\/span> and a cohesive population of large anaplastic cells is observed.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"Linfomatoide papulosis es uno de los dos primario cut\u00e1neo Linfomas cut\u00e1neos CD30 positivos, seg\u00fan la clasificaci\u00f3n de la OMS \/ EORTC. Histolog\u00eda de papulosis linfomatoide Poder de escaneo del patolog\u00eda…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-16690","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16690","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=16690"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16690\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=16690"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=16690"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=16690"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}