{"id":16736,"date":"2020-04-29T09:29:11","date_gmt":"2020-04-29T12:29:11","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/wiki\/patologia-del-matricoma-melanocitico\/"},"modified":"2020-05-03T10:31:19","modified_gmt":"2020-05-03T13:31:19","slug":"pathology-of-melanocytic-matricoma","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-del-matricoma-melanocitico\/","title":{"rendered":"Pathology of melanocytic matricoma"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-del-matricoma-melanocitico\/#Histologia-del-matricoma-melanocitico\" >Histology of melanocytic matricoma<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-del-matricoma-melanocitico\/#Patologia-del-matricoma-melanocitico\" >Pathology of melanocytic matricoma<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-del-matricoma-melanocitico\/#Estudios-especiales-de-matricoma-melanocitico\" >Special studies of melanocytic matricoma.<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-del-matricoma-melanocitico\/#Diagnostico-diferencial-del-matricoma-melanocitico\" >Differential diagnosis of melanocytic matricoma<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<p><span class=\"term\" data-term-id=\"785\">Melanocytic<\/span> the matrix is a rare <span class=\"term\" data-term-id=\"289\">tumor<\/span> which is presented as a small strongly <span class=\"term\" data-term-id=\"1520\">pigmented<\/span> tumor. Clinically mimics <span class=\"term\" data-term-id=\"733\">nodular<\/span> <span class=\"term\" data-term-id=\"1670\">melanoma<\/span>, <span class=\"term\" data-term-id=\"360\">hemangioma<\/span> and other pigmented tumors. Until now, these tumors have exhibited a <span class=\"term\" data-term-id=\"22\">benign<\/span> clinical course.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Histologia-del-matricoma-melanocitico\"><\/span>\n<span class=\"term\" data-term-id=\"128\">Histology<\/span> of melanocytic matricoma<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The sections through the melanocytic matrix show a good<span class=\"term\" data-term-id=\"37\">circumscribed<\/span> <span class=\"term\" data-term-id=\"52\">dermal<\/span> tumor that can invade and erode the overlying layer <span class=\"term\" data-term-id=\"85\">epidermis<\/span> (Figure 1). There is heavy <span class=\"term\" data-term-id=\"180\">melanin<\/span> <span class=\"term\" data-term-id=\"370\">statement<\/span>. The tumor is made up of <span class=\"term\" data-term-id=\"1654\">basaloid<\/span> cells with some <span class=\"term\" data-term-id=\"1612\">nuclear<\/span> <span class=\"term\" data-term-id=\"1539\">pleomorphism<\/span> and conspicuous <span class=\"term\" data-term-id=\"1536\">mitotic<\/span> exercise. Intermixed with these <span class=\"term\" data-term-id=\"847\">epithelial<\/span> cells are a dendritic population <span class=\"term\" data-term-id=\"181\">melanocytes<\/span> (Figures 1-4). There is <span class=\"term\" data-term-id=\"489\">focal<\/span> &quot;Ghost cell&quot; <span class=\"term\" data-term-id=\"156\">keratinization<\/span> (Figures 5, 6).<\/p>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Patologia-del-matricoma-melanocitico\"><\/span>Pathology of melanocytic matricoma<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='melanocytic-matricoma-1__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-4993984-5385729' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/melanocytic-matricoma-1__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-4993984.jpg'>\n<\/div>\n<p class=\"p-small\">Figure 1<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='melanocytic-matricoma-2__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-5005958-4481472' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/melanocytic-matricoma-2__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-5005958.jpg'>\n<\/div>\n<p class=\"p-small\">Figure 2<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='melanocytic-matricoma-3__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-9558953-5830692' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/melanocytic-matricoma-3__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-9558953.jpg'>\n<\/div>\n<p class=\"p-small\">figure 3<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='melanocytic-matricoma-4__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-5565221-4793209' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/melanocytic-matricoma-4__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-5565221.jpg'>\n<\/div>\n<p class=\"p-small\">Figure 4<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='melanocytic-matricoma-5__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-6922287-2833147' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/melanocytic-matricoma-5__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-6922287.jpg'>\n<\/div>\n<p class=\"p-small\">Figure 5<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='melanocytic-matricoma-6__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-6623017-9433363' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/melanocytic-matricoma-6__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-6623017.jpg'>\n<\/div>\n<p class=\"p-small\">Figure 6<\/p>\n<\/p><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Estudios-especiales-de-matricoma-melanocitico\"><\/span>Special studies of melanocytic matricoma.<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span class=\"term\" data-term-id=\"155\">Curb<\/span> The spots confirm that the tumor is epithelial (rather than melanoma). Melanocytic spots demonstrate a population of intertwined dendritic melanocytes.<\/p>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Diagnostico-diferencial-del-matricoma-melanocitico\"><\/span>\n<span class=\"term\" data-term-id=\"813\">Differential diagnosis<\/span> of melanocytic matricoma<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Melanoma: These tumors can simulate melanoma clinically and <span class=\"term\" data-term-id=\"1669\">histologically<\/span> (The case illustrated here was initially diagnosed with melanoma both clinically and histologically). Immunohistochemical studies may help to exclude this possibility. Keratinization should not be seen in melanoma.<\/p>\n<p><span class=\"term\" data-term-id=\"831\">Basal<\/span> cell <span class=\"term\" data-term-id=\"32\">carcinoma<\/span> - BCC can show matrical focal <span class=\"term\" data-term-id=\"1307\">differentiation<\/span>. However, other features such as stromal retraction and <span class=\"term\" data-term-id=\"1374\">peripheral<\/span> the stockade must be seen with BCC.<\/p>\n<p><span class=\"term\" data-term-id=\"176\">Evil one<\/span> matricoma <span class=\"term\" data-term-id=\"1742\">Malignancy<\/span> in matrix tumors it may be difficult to exclude in small <span class=\"term\" data-term-id=\"1111\">biopsies<\/span> given the marked pleomorphism and <span class=\"term\" data-term-id=\"1535\">mitosis<\/span> which are common in benign matrical tumors. Deep invasion <span class=\"term\" data-term-id=\"403\">necrosis<\/span> and the large clinical size can be useful features to diagnose a malignant tumor.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>Melanoc\u00edtico el matricoma es un raro tumor que se presenta como un peque\u00f1o fuertemente pigmentado tumor. Cl\u00ednicamente imita nodular melanoma, hemangioma y otros tumores pigmentados. Hasta ahora, estos tumores han&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-16736","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16736","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=16736"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/16736\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=16736"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=16736"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=16736"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}