{"id":6519,"date":"2020-04-22T01:52:25","date_gmt":"2020-04-22T04:52:25","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/hipoqueratosis-palmar-circunscrita\/"},"modified":"2020-04-27T17:26:18","modified_gmt":"2020-04-27T20:26:18","slug":"circumscribed-palmar-hypokeratosis","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/hipoqueratosis-palmar-circunscrita\/","title":{"rendered":"Circumscribed palmar hypokeratosis"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/hipoqueratosis-palmar-circunscrita\/#Que-es-circunscrito-de-la-palma-hipoqueratosis\" >What is circumscribed hypokeratosis of the palm?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/hipoqueratosis-palmar-circunscrita\/#%C2%BFQuien-contrae-hipoqueratosis-palmar-circunscrita\" >Who gets circumscribed palmar hypokeratosis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/hipoqueratosis-palmar-circunscrita\/#%C2%BFQue-causa-la-hipoqueratosis-palmar-circunscrita\" >What causes circumscribed palmar hypokeratosis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/hipoqueratosis-palmar-circunscrita\/#%C2%BFCuales-son-las-caracteristicas-clinicas-de-la-hipoqueratosis-palmar-circunscrita\" >What are the clinical characteristics of circumscribed palmar hypokeratosis?<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/hipoqueratosis-palmar-circunscrita\/#Hipoqueratosis-palmar-circunscrita\" >Circumscribed palmar hypokeratosis<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/hipoqueratosis-palmar-circunscrita\/#%C2%BFComo-se-diagnostica-la-hipoqueratosis-palmar-circunscrita\" >How is circumscribed palmar hypokeratosis diagnosed?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/hipoqueratosis-palmar-circunscrita\/#%C2%BFCual-es-el-tratamiento-de-la-hipoqueratosis-palmar-circunscrita\" >What is the treatment of circumscribed palmar hypokeratosis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/hipoqueratosis-palmar-circunscrita\/#%C2%BFCual-es-el-resultado-de-la-hipoqueratosis-palmar-circunscrita\" >What is the result of circumscribed palmar hypokeratosis?<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<h2><span class=\"ez-toc-section\" id=\"Que-es-circunscrito-de-la-palma-hipoqueratosis\"><\/span>What is it <span class=\"term\" data-term-id=\"37\">circumscribed<\/span> <span class=\"term\" data-term-id=\"585\">palm<\/span> hypokeratosis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"Default\">Circumscribed palmar hypokeratosis is a rare, persistent, solitary, red <span class=\"term\" data-term-id=\"224\">patch<\/span> thin skin on the hand.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQuien-contrae-hipoqueratosis-palmar-circunscrita\"><\/span>Who gets circumscribed palmar hypokeratosis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"Default\">To date, about 50 cases of circumscribed palmar hypokeratosis have been described in the medical literature. It predominantly affects women in the fourth to seventh decade of life. A <span class=\"term\" data-term-id=\"1036\">congenital<\/span> The case has been described.<\/p>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-causa-la-hipoqueratosis-palmar-circunscrita\"><\/span>What causes circumscribed palmar hypokeratosis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"Default\">The cause of circumscribed palmar hypokeratosis is unknown.<\/p>\n<ul>\n<li>One case reported an association with human papillomavirus (HPV) type 4, which is a cause of viral warts, but the significance of this finding is unclear.  <\/li>\n<li>A <span class=\"term\" data-term-id=\"324\">located<\/span> waste of <span class=\"term\" data-term-id=\"956\">cellular<\/span> <span class=\"term\" data-term-id=\"822\">accession<\/span> possible, causing abrupt loss or detachment of the stratum corneum layer <span class=\"term\" data-term-id=\"85\">epidermis<\/span>.<\/li>\n<li>Abnormal <span class=\"term\" data-term-id=\"156\">keratinization<\/span> or abnormal <span class=\"term\" data-term-id=\"917\">keratinocytes<\/span> <span class=\"term\" data-term-id=\"1307\">differentiation<\/span> They have also been implicated.<\/li>\n<li>A couple of cases have been associated with <span class=\"term\" data-term-id=\"1365\">trauma<\/span> (and were called \u201cpalmar pseudo circumscribed \/<span class=\"term\" data-term-id=\"588\">plant<\/span> hypokeratosis).<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCuales-son-las-caracteristicas-clinicas-de-la-hipoqueratosis-palmar-circunscrita\"><\/span>What are the clinical characteristics of circumscribed palmar hypokeratosis? <span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"Default\">Circumscribed palmar hypokeratosis occurs most frequently on the thenar or hypothenar eminence of the palm, the sole of the foot (plantar aspect), or less frequently the palmar aspect of the fingers. Very rarely, it may affect the skin on the back of the fingers or not.<span class=\"term\" data-term-id=\"496\">acral<\/span> skin sites. There are some reports of cases with more than one. <span class=\"term\" data-term-id=\"164\">injury<\/span> which affects both the palms or palms and the fingers or palms and soles of the feet.<\/p>\n<p class=\"Default\">Circumscribed palmar hypokeratosis has a thin pink central area <span class=\"term\" data-term-id=\"809\">atrophic<\/span>soft or slightly <span class=\"term\" data-term-id=\"385\">scaly<\/span> skin, while at the edge there is an abrupt transition to normal skin.<\/p>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Hipoqueratosis-palmar-circunscrita\"><\/span>Circumscribed palmar hypokeratosis<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='palmar-hypokeratosis-01__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingilde5xq-9648640-5485056' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/palmar-hypokeratosis-01__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDE5XQ-9648640.jpg'>\n<\/div>\n<p class=\"p-small\">Circumscribed palmar hypokeratosis<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='palmar-hypokeratosis-02__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingilde5xq-4077722-8559769' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/palmar-hypokeratosis-02__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDE5XQ-4077722.jpg'>\n<\/div>\n<p class=\"p-small\">Circumscribed palmar hypokeratosis<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='palmar-hypokeratosis-03__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingilde5xq-2331482-3584099' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/palmar-hypokeratosis-03__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDE5XQ-2331482.jpg'>\n<\/div>\n<p class=\"p-small\">Circumscribed palmar hypokeratosis<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='palmar-hypokeratosis-04__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildg1xq-1541462-2265868' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/palmar-hypokeratosis-04__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDg1XQ-1541462.jpg'>\n<\/div>\n<p class=\"p-small\">Circumscribed palmar hypokeratosis<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='palmar-hypokeratosis-05__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-8301828-7447237' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/palmar-hypokeratosis-05__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-8301828.jpg'>\n<\/div>\n<p class=\"p-small\">Circumscribed palmar hypokeratosis<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='palmar-hypokeratosis-06__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingilde5xq-1090288-1950984' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/palmar-hypokeratosis-06__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDE5XQ-1090288.jpg'>\n<\/div>\n<p class=\"p-small\">Circumscribed palmar hypokeratosis<\/p>\n<\/p><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFComo-se-diagnostica-la-hipoqueratosis-palmar-circunscrita\"><\/span>How is circumscribed palmar hypokeratosis diagnosed?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"Default\">Circumscribed palmar hypokeratosis can be diagnosed on its distinctive clinical appearance.<\/p>\n<p class=\"Default\">A <span class=\"term\" data-term-id=\"24\">biopsy<\/span> can be taken across the edge of a lesion. This shows that the epidermis in the central area of the affected skin lacks <span class=\"term\" data-term-id=\"273\">stratum corneum<\/span> (<span class=\"term\" data-term-id=\"131\">horny layer<\/span>) At the edge of the lesion there is a very sharp abrupt transition to the normal compact orthohypekeratosis, typical of the palmar skin. They do not exist <span class=\"term\" data-term-id=\"474\">histological<\/span> findings suggestive of HPV <span class=\"term\" data-term-id=\"145\">infection<\/span>.<\/p>\n<p class=\"Default\">The main differential diagnoses to consider in circumscribed palmar hypokeratosis are porokeratosis and <span class=\"term\" data-term-id=\"270\">scaly<\/span> cell <span class=\"term\" data-term-id=\"32\">carcinoma<\/span> <span class=\"term\" data-term-id=\"863\">in the place<\/span>.<\/p>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCual-es-el-tratamiento-de-la-hipoqueratosis-palmar-circunscrita\"><\/span>What is the treatment of circumscribed palmar hypokeratosis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"Default\">No treatment is required for circumscribed palmar hypokeratosis. However:<\/p>\n<ul>\n<li>Regular application of <span class=\"term\" data-term-id=\"1330\">current<\/span> calcipotriol (calcipotriene) 0.05%  <span class=\"term\" data-term-id=\"1121\">cream<\/span> It can flatten the sharp cut at the edge of the lesion, leaving a thin, flat, pink patch of skin.<\/li>\n<li>5-Fluorouracil cream, <span class=\"term\" data-term-id=\"1145\">cryotherapy<\/span> and <span class=\"term\" data-term-id=\"1571\">photodynamic<\/span> Therapy (PDT) has been reported to be partially effective in individual cases.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCual-es-el-resultado-de-la-hipoqueratosis-palmar-circunscrita\"><\/span>What is the result of circumscribed palmar hypokeratosis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"Default\">Circumscribed palmar hypokeratosis is a <span class=\"term\" data-term-id=\"319\">chronic<\/span> condition that persists unchanged over time or that may enlarge very slowly. There are no reports of <span class=\"term\" data-term-id=\"30\">Cancer<\/span> developing within the lesions.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>Que es circunscrito de la palma hipoqueratosis? La hipoqueratosis palmar circunscrita es un raro, persistente, solitario, rojo parche de piel delgada en la mano. \u00bfQui\u00e9n contrae hipoqueratosis palmar circunscrita? Hasta&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-6519","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6519","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=6519"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6519\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=6519"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=6519"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=6519"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}