<\/span><\/h2>\nComedones are small, skin-colored bumps (papules<\/span>) is frequently found on the forehead and chin of people with acne. A single injury<\/span> is a comedo<\/span>.<\/p>\n\n- Open comedones are blackheads; black on the surface pigment<\/span> (melanin<\/span>), instead of dirt<\/li>\n
- Closed comedones are whiteheads; the follicle<\/span> is completely blocked<\/li>\n
- Microcomedones are so small that they are not visible to the naked eye.<\/li>\n
- Macrocomedones are closed facial comedones greater than 2\u20133 mm in diameter.<\/li>\n
- A giant comedo is a type of cyst<\/span> in which there is a clear opening similar to a black dot on the skin<\/li>\n
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Sun comedones are found on the cheeks and chin of older people, and are believed to be due to sun damage.<\/li>\n<\/ul>\n\n<\/span>Comedones<\/span><\/h5>\n<\/section>\n\n\n
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Open comedones<\/p>\n
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Closed comedones<\/p>\n
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Giant comedo<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>What is comedonal acne?<\/span><\/h2>\nComedonal acne is an acne pattern in which most lesions are comedones. Comedonal acne most often affects the forehead and chin.<\/p>\n\n<\/span>Comedonal acne<\/span><\/h5>\n<\/section>\n\n\n
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Open comedones<\/p>\n
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Comedonal acne<\/p>\n
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Comedonal acne<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>What Causes Comedones?<\/span><\/h2>\nComedones arise when the cells lining the sebaceous<\/span> ducts proliferate (cornification), and increases tallow<\/span> production. A comedo is made up of debris that blocks the sebaceous duct and hair<\/span> follicle. Comedones are now known to involve inflammation<\/span> (See causes of acne).<\/p>\nThe development of comedones can involve the following factors:<\/p>\n
\n- Excessive activity of the male. sex<\/span> hormone 5-testosterone<\/span> (DHT) inside skin cells<\/li>\n
- Reduced linoleate (the salt of the essential fatty acid, linoleic acid) in the sebum causing more scale<\/span> and reduced barrier function<\/li>\n
- \nProinflammatory<\/span> cytokines<\/span> (cell signaling proteins), such as Interleukin<\/span> 1 (IL-1) and IL-8, produced by cells lining the follicle in response to activation of the innate immune system<\/li>\n
- Free fatty acids made from acne sebum bacteria<\/span>\n<\/li>\n
- Premenstrually overhydrated skin, from moisturizers or in damp<\/span> terms<\/li>\n
- Contact with certain chemicals, including oils ointments<\/span>, isopropyl myristate, propylene glycol and some colorants in cosmetics<\/li>\n
- Rupture of the follicle from injuries such as squeezing pimples, abrasive scrubbing, chemical peels or To be<\/span> deals<\/li>\n
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Smoking: Comedonal acne is more common in smokers than non-smokers<\/li>\n
- Certain dietary factors can contribute to comedonal acne, particularly dairy products and foods with a high glycemic index (sugars and fats)<\/li>\n<\/ul>\n
<\/span>What is the treatment for comedonal acne?<\/span><\/h2>\nIf you have comedonal acne, choose oil-free cosmetics and wash them twice a day with mild soap and water. It is better to quit smoking and eat a diet low in sugar, fat, and dairy.<\/p>\n
Choose "comedolytic" current<\/span> Medications These should be applied once or twice a day as a thin spot all over the affected area. It may take several weeks or months for a worthwhile improvement to occur. Treatment must be continued long term (sometimes for many years).<\/p>\nSuitable topical agents include:<\/p>\n