{"id":6611,"date":"2020-04-22T10:58:49","date_gmt":"2020-04-22T13:58:49","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/patologia-de-la-criptococosis\/"},"modified":"2020-05-03T18:25:06","modified_gmt":"2020-05-03T21:25:06","slug":"cryptococcosis-pathology","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-de-la-criptococosis\/","title":{"rendered":"Cryptococcosis pathology"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-de-la-criptococosis\/#Histologia-de-la-criptococosis\" >Cryptococcosis histology<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-de-la-criptococosis\/#Patologia-de-la-criptococosis\" >Cryptococcosis pathology<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-de-la-criptococosis\/#Manchas-especiales-para-la-criptococosis\" >Special spots for cryptococcosis.<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-de-la-criptococosis\/#Diagnostico-diferencial-de-la-criptococosis-patologia\" >Differential diagnosis of cryptococcosis pathology<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<p>Cryptococcosis is a <span class=\"term\" data-term-id=\"380\">systemic<\/span> disease caused by the yeast fungus Cryptococcus neoformans. Is a <span class=\"term\" data-term-id=\"1705\">encapsulated<\/span> yeast that has five serotypes, A, B, C, D and AD, of two varieties called neoformans (A, D and AD) and gatii (B and C). The latter is more <span class=\"term\" data-term-id=\"1676\">predominant<\/span> in Australasia<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Histologia-de-la-criptococosis\"><\/span>\n<span class=\"term\" data-term-id=\"128\">Histology<\/span> from cryptococcosis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Yeast forms of cryptococcosis are generally surrounded by massive gelatinous <span class=\"term\" data-term-id=\"201\">edema<\/span> (figure 1, arrow). The around <span class=\"term\" data-term-id=\"490\">inflammatory<\/span> the reaction depends on the stage of the clinic <span class=\"term\" data-term-id=\"164\">injury<\/span> and on the immune status of the patient. Immunocompetent patients can cause rapid <span class=\"term\" data-term-id=\"1076\">granulomatous<\/span> answer in which the <span class=\"term\" data-term-id=\"883\">organisms<\/span> can be difficult to see without special stains, while <span class=\"term\" data-term-id=\"1695\">immunocompromised<\/span> patients show minimal <span class=\"term\" data-term-id=\"148\">inflammation<\/span> and edema around the numerous forms of yeast as seen in the case illustrated here (Figure 2). The yeast forms of cryptococcosis are often widely separated by their thick mucoid capsules. The PAS stain decorates the yeast (Figure 3) and the mucicarmine stain decorates the highly characteristic gelatinous capsule of a bright pink (Figure 4).<\/p>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Patologia-de-la-criptococosis\"><\/span>Cryptococcosis pathology<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='cryptococcus-figure-1__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildi1xq-4051191-7841041' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/cryptococcus-figure-1__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDI1XQ-4051191.jpg'>\n<\/div>\n<p class=\"p-small\">Figure 1<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='crypto-figure-2__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-5389779-6245023' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/crypto-figure-2__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-5389779.jpg'>\n<\/div>\n<p class=\"p-small\">Figure 2<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='cryptococcus-figure-3__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildbd-1499516-2622447' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/cryptococcus-figure-3__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDBd-1499516.jpg'>\n<\/div>\n<p class=\"p-small\">figure 3<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='cryptococcus-figure-4__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-6957040-3252258' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/cryptococcus-figure-4__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-6957040.jpg'>\n<\/div>\n<p class=\"p-small\">Figure 4<\/p>\n<\/p><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Manchas-especiales-para-la-criptococosis\"><\/span>Special spots for cryptococcosis.<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The cryptococcus capsule is heavily stained with the mucicarmine stain (Figure 4). Grocott, mucicarmine, methanamine silver, toluidine blue or methylene blue are sometimes required to help illustrate the characteristic budding yeasts. This is especially useful in immunocompetent <span class=\"term\" data-term-id=\"1314\">Hosts<\/span> with a rapid inflammatory response<\/p>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Diagnostico-diferencial-de-la-criptococosis-patologia\"><\/span>\n<span class=\"term\" data-term-id=\"813\">Differential diagnosis<\/span> from cryptococcosis <span class=\"term\" data-term-id=\"223\">pathology<\/span><br \/>\n<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Histoplasmosis and blastomycosis: the positivity of mucicarmine discriminates cryptococcus from these other organisms. The situation can be complicated by the rare cryptococcal strain that lacks a capsule. In case of cryptococcal doubt <span class=\"term\" data-term-id=\"411\">antigens<\/span> can be identified with the latex agglutination of <span class=\"term\" data-term-id=\"863\">in the place<\/span> Hybridization can be used.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>La criptococosis es un sist\u00e9mico enfermedad causada por el hongo levadura Cryptococcus neoformans. Es un encapsulado levadura que tiene cinco serotipos, A, B, C, D y AD, de dos variedades&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-6611","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6611","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=6611"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6611\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=6611"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=6611"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=6611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}