{"id":6693,"date":"2020-04-22T19:03:08","date_gmt":"2020-04-22T22:03:08","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/tumor-de-celulas-granulares\/"},"modified":"2020-04-27T17:08:09","modified_gmt":"2020-04-27T20:08:09","slug":"granular-cell-tumor","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/tumor-de-celulas-granulares\/","title":{"rendered":"Granular cell tumor"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/tumor-de-celulas-granulares\/#%C2%BFQue-es-una-celula-granular-tumor\" >What is a granule cell? tumor?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/tumor-de-celulas-granulares\/#%C2%BFDonde-se-produce-un-tumor-de-celulas-granulares\" >Where does a granular cell tumor occur?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/tumor-de-celulas-granulares\/#%C2%BFCuales-son-las-caracteristicas-clinicas-de-cutaneo-tumor-de-celulas-granulares\" >What are the clinical characteristics of cutaneous granular cell tumor?<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/tumor-de-celulas-granulares\/#Tumores-de-celulas-granulares\" >Granular cell tumors<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/tumor-de-celulas-granulares\/#%C2%BFQuien-contrae-tumor-de-celulas-granulares\" >Who gets granular cell tumor?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/tumor-de-celulas-granulares\/#%C2%BFQue-pruebas-se-requieren\" >What tests are required?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/tumor-de-celulas-granulares\/#%C2%BFCual-es-el-tratamiento-del-tumor-de-celulas-granulares\" >What is the treatment of granular cell tumor?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/tumor-de-celulas-granulares\/#Cual-es-el-pronostico-para-el-tumor-de-celulas-granulares\" >What is the prognosis for granular cell tumor?<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-es-una-celula-granular-tumor\"><\/span>What is a granule cell? <span class=\"term\" data-term-id=\"289\">tumor<\/span>?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>A granular cell tumor is rare, usually <span class=\"term\" data-term-id=\"22\">benign<\/span> tumor previously known as granular cell myoblastoma. Their origin has been debated since their first description, but it is now generally believed that they originate in Schwann cells (cells that provide myelin insulation to <span class=\"term\" data-term-id=\"952\">nerves<\/span>)<\/p>\n<p>They are called granular cell tumors because of their appearance under the microscope.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFDonde-se-produce-un-tumor-de-celulas-granulares\"><\/span>Where does a granular cell tumor occur?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Granular cell tumors occur in the skin or <span class=\"term\" data-term-id=\"900\">subcutaneous<\/span> tissue in 30 to 40% of cases. Approximately 50% occurs in the head and neck with almost 25% in the tongue. However, they can occur on any skin or <span class=\"term\" data-term-id=\"1018\">mucous membrane<\/span> site and occasionally affect internal organs.<\/p>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCuales-son-las-caracteristicas-clinicas-de-cutaneo-tumor-de-celulas-granulares\"><\/span>What are the clinical characteristics of <span class=\"term\" data-term-id=\"47\">cutaneous<\/span> granular cell tumor?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>A granular cell tumor is usually solitary, small (usually 1 to 3 cm), and painless. Occasionally mild itching or tenderness is described. They usually appear as a colored skin that grows slowly <span class=\"term\" data-term-id=\"198\">nodule<\/span> With a smooth or slightly rough surface.<\/p>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Tumores-de-celulas-granulares\"><\/span>Granular cell tumors<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='granular-cell1__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-9575966-6273040' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/granular-cell1__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-9575966.jpg'>\n<\/div>\n<p class=\"p-small\">Granular cell tumor<\/p>\n<\/p><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQuien-contrae-tumor-de-celulas-granulares\"><\/span>Who gets granular cell tumor?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Granular cell tumors can occur in anyone, however, they tend to be more common in women and dark-skinned people. Most tend to develop between the third and fifth decades of life.<\/p>\n<p>Multiple granular cell tumors can occur in up to 25% cases and it is in these patients that associations with other conditions are occasionally made. There appears to be an association with multiple <span class=\"term\" data-term-id=\"1394\">lentigines<\/span>, and cases have been reported in patients with a definitive diagnosis of Noonan <span class=\"term\" data-term-id=\"350\">syndrome<\/span>, <span class=\"term\" data-term-id=\"876\">neurofibromatosis<\/span> type I and Leopard syndrome. <span class=\"term\" data-term-id=\"849\">Family<\/span> Cases of multiple granular cell tumors also occur.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-pruebas-se-requieren\"><\/span>What tests are required?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The diagnosis of granular cell tumor is made through the skin. <span class=\"term\" data-term-id=\"24\">biopsy<\/span>. <span class=\"term\" data-term-id=\"129\">Histopathology<\/span> reveals features <span class=\"term\" data-term-id=\"520\">granules<\/span> within <span class=\"term\" data-term-id=\"838\">cytoplasm<\/span> of large tumor cells.<\/p>\n<p>A general medical history and examination to exclude any potentially associated conditions are helpful.<\/p>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCual-es-el-tratamiento-del-tumor-de-celulas-granulares\"><\/span>What is the treatment of granular cell tumor?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Very often surgical <span class=\"term\" data-term-id=\"848\">excision<\/span> of the tumor will provide a diagnosis and treatment of choice.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Cual-es-el-pronostico-para-el-tumor-de-celulas-granulares\"><\/span>Which is the <span class=\"term\" data-term-id=\"241\">forecast<\/span> for granular cell tumor?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>More than 98% granular cell tumors are benign and should be cured after complete excision. <span class=\"term\" data-term-id=\"176\">Evil one<\/span> change has been reported very rarely and tends to be more reliably predicted by aggressive clinical features (rapid growth, size greater than 4 cm, <span class=\"term\" data-term-id=\"403\">necrosis<\/span>, <span class=\"term\" data-term-id=\"1774\">lymph node<\/span> participation) instead of <span class=\"term\" data-term-id=\"474\">histological<\/span> characteristics. Therefore, large or aggressively growing tumors should be followed postoperatively.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>\u00bfQu\u00e9 es una c\u00e9lula granular? tumor? Un tumor de c\u00e9lulas granulares es poco com\u00fan, generalmente benigno tumor previamente conocido como mioblastoma de c\u00e9lulas granulares. Su origen se ha debatido desde&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-6693","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6693","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=6693"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6693\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=6693"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=6693"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=6693"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}