<\/span><\/h2>\nAcanthosis nigricans is a skin disorder characterized by darkening (hyperpigmentation<\/span>) and thickening (hyperkeratosis<\/span>) of the skin, which occurs primarily in the skin folds in the armpit (armpit<\/span>), groin and back of the neck.<\/p>\nAcanthosis nigricans is not a skin disease per se but a cutaneous<\/span> sign<\/span> of an underlying condition or disease.<\/p>\nThere are two major types of acanthosis: benign<\/span> and evil one<\/span>. Although it is classically described as a sign of internal malignancy<\/span>This is very extrange. The benign types, sometimes described as \u201cpseudoacanthosis nigricans,\u201d are much more common.<\/p>\n<\/span>What causes acanthosis nigricans?<\/span><\/h2>\nThe cause of acanthosis nigricans is not yet clearly defined, but it appears to be related to insulin<\/span> endurance. It has been associated with several benign and malignant conditions. According to the predisposing conditions, acanthosis nigricans has been divided into 7 types.<\/p>\n\n\n\n| Types of acanthosis nigricans<\/th>\n<\/tr>\n |
\n| Kind<\/th>\n | Characteristics<\/th>\n<\/tr>\n |
\n| Acanthosis nigricans associated with obesity<\/td>\n | \n\n- Most common type of acanthosis nigricans<\/span>\n<\/li>\n
- It can occur at any age, but is more common in adulthood.<\/li>\n
- Obesity often caused by insulin resistance.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
\n| Syndromic acanthosis nigricans<\/td>\n | \n\n- Defined as acanthosis nigricans<\/span> which is associated with a syndrome<\/span>, such as hyperinsulinemia, Cushing's syndrome, polycystic ovary syndrome, total lipodystrophy, Crouzon syndrome\n<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
\n| Benign acanthosis nigricans<\/td>\n | \n\n- Also know as acral<\/span> acanthotic anomaly<\/li>\n
- Thick and velvety injury<\/span> more prominent over the upper surface of the hands and feet in healthy patients<\/li>\n
- More common in dark-skinned people, especially those of African American descent.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
\n| Drug-induced acanthosis nigricans<\/td>\n | \n\n- Uncommon, but acanthosis nigricans<\/span> can be induced by various medications, including nicotinic acid, insulin, systemic<\/span> corticosteroids and hormonal treatments<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
\n| \nHereditary<\/span> benign acanthosis nigricans<\/td>\n | \n\n- \nAcanthosis nigricans<\/span> inherited as a autosomal<\/span> dominant characteristic<\/li>\n
- Lesions can manifest at any age, infancy, childhood or adulthood.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
\n| Malignant acanthosis nigricans<\/td>\n | \n\n- \nAcanthosis nigricans<\/span> associated with internal malignancy<\/li>\n
- Most common underlying Cancer<\/span> it is tumor<\/span> of the intestine (90%) especially stomach cancer<\/li>\n
- In 25-50% cases, lesions are present in the mouth on the tongue and lips.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
\n| Acanthosis nigricans mixed type<\/td>\n | \n\n- Patients with a type of acanthosis nigricans<\/span> who also develop new lesions of a different cause, e.g. overweight patient with associated obesity acanthosis nigricans<\/span> who then develops malignant AN<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\n \n \n \n<\/div><\/div><\/div><\/div>\n <\/span>What are the characteristics of acanthosis nigricans?<\/span><\/h2>\n\n- Thick patches of brown skin with a velvety texture that can appear anywhere but most often appear in skin folds in the armpit, groin, and back of the neck.<\/li>\n
- \nPapillomatosis<\/span> (multiple finger-like growths) is common in cutaneous and mucous membrane<\/span> surfaces<\/li>\n
- Skin tags are often found in and around the affected areas.<\/li>\n
- \nPruritus<\/span> (itching) may be present, particularly in acanthosis nigricans associated with malignancy (paraneoplastic<\/span> pruritus).<\/li>\n
- \nAcanthosis nigricans<\/span> Lesions may also appear in the mucous<\/span> membranes of the oral, nasal and laryngeal cavities mucous membrane<\/span> and esophagus<\/li>\n
- Lesions involving the mucosa, palms, and soles tend to be more extensive and more severe when malignant. acanthosis nigricans<\/span>.<\/li>\n
- Patients with malignancy acanthosis nigricans<\/span> They tend to be middle-aged, non-obese, and the lesions develop abruptly.<\/li>\n<\/ul>\n\n
<\/span>Acanthosis nigricans<\/span><\/h5>\n<\/section>\n\n\n \n  \n<\/div>\n Acanthosis nigricans<\/p>\n \n  \n<\/div>\n Acanthosis nigricans<\/p>\n \n  \n<\/div>\n Acanthosis nigricans<\/p>\n \n  \n<\/div>\n Acanthosis nigricans<\/p>\n \n  \n<\/div>\n Acanthosis nigricans<\/p>\n \n  \n<\/div>\n Acanthosis nigricans<\/p>\n<\/p><\/div>\n<\/section>\n <\/div>\n <\/span>What is the work for acanthosis nigricans?<\/span><\/h2>\nIt is very important to differentiate acanthosis nigricans related to malignancy from that related to benign conditions. Malignant tumors acanthosis nigricans<\/span> They are usually very aggressive and spread quickly. Death often occurs shortly afterward. If it is malignant acanthosis nigricans<\/span> It is suspected that in a patient without known cancer, it is extremely important to perform a thorough workup of the underlying malignancy and identify an occult tumor. If the tumor can be treated successfully, the condition may resolve.<\/p>\nOther causes of acanthosis nigricans<\/span> It can be identified by detecting insulin resistance and diabetes mellitus.<\/p>\n<\/span>What is the treatment for acanthosis nigricans?<\/span><\/h2>\nthe primary<\/span> The goal of treatment is to correct the underlying disease process. Correcting the underlying cause often results in resolution of the injuries.<\/p>\n\n- Correct hyperinsulinemia through diet and medications.<\/li>\n
- Lose weight with associated obesity acanthosis nigricans<\/span>\n<\/li>\n
- Excise or treat the underlying tumor<\/li>\n
- Stop Offending Drug-Induced Medications acanthosis nigricans<\/span>\n<\/li>\n<\/ul>\n
in hereditary acanthosis nigricans<\/span>, lesions tend to gradually enlarge before stabilizing and\/or returning on their own.<\/p>\nThere is no specific treatment for acanthosis nigricans<\/span>. The treatments considered are primarily used to improve cosmetic appearance and include current<\/span> retinoids<\/span>, dermabrasion and To be<\/span> therapy.<\/p>\nFinal result of acanthosis nigricans<\/span> varies depending on the cause of acanthosis nigricans<\/span>. Benign conditions, either on their own or through lifestyle changes and\/or treatment, have good outcomes. However the forecast<\/span> for patients with malignancy acanthosis nigricans<\/span> He is often poor. The associated cancer is often advanced and the average survival of these patients is approximately 2 years.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"Que es acantosis nigricans? La acantosis nigricans es un trastorno de la piel caracterizado por oscurecimiento (hiperpigmentaci\u00f3n) y engrosamiento (hiperqueratosis) de la piel, que ocurre principalmente en los pliegues de…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-6700","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6700","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=6700"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6700\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=6700"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=6700"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=6700"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}} | | | | | | |