{"id":6800,"date":"2020-04-23T05:52:05","date_gmt":"2020-04-23T08:52:05","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/enfermedad-de-behcet-2\/"},"modified":"2020-04-27T16:52:27","modified_gmt":"2020-04-27T19:52:27","slug":"behcet-disease-2-2","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-behcet-2\/","title":{"rendered":"Beh\u00e7et&#039;s disease"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-behcet-2\/#%C2%BFQue-es-la-enfermedad-de-Behcet\" >What is Beh\u00e7et&#039;s disease?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-behcet-2\/#%C2%BFQue-causa-la-enfermedad-de-Behcet\" >What causes Beh\u00e7et&#039;s disease?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-behcet-2\/#%C2%BFQuien-esta-en-riesgo-de-contraer-la-enfermedad-de-Behcet\" >Who is at risk for Beh\u00e7et&#039;s disease?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-behcet-2\/#%C2%BFCuales-son-los-signos-y-sintomas-de-la-enfermedad-de-Behcet\" >What are the signs and symptoms of Beh\u00e7et&#039;s disease?<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-behcet-2\/#Enfermedad-de-Behcet\" >Behcet&#039;s disease<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-behcet-2\/#%C2%BFComo-se-diagnostica-la-enfermedad-de-Behcet\" >How is Beh\u00e7et&#039;s disease diagnosed?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-behcet-2\/#%C2%BFCual-es-el-tratamiento-para-la-enfermedad-de-Behcet\" >What is the treatment for Beh\u00e7et&#039;s disease?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-behcet-2\/#Cual-es-el-pronostico\" >What is the prognosis?<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-es-la-enfermedad-de-Behcet\"><\/span>What is Beh\u00e7et&#039;s disease?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Beh\u00e7et&#039;s disease (or <span class=\"term\" data-term-id=\"350\">syndrome<\/span>) is a rare disease characterized by pain in the mouth <span class=\"term\" data-term-id=\"1279\">ulcers<\/span>, genital ulcers, eye problems and skin lesions. The condition is named after the Turk <span class=\"term\" data-term-id=\"54\">dermatologist<\/span> Hulusi Beh\u00e7et, who first described the disease in 1924. It is also known as <span>Adamantiades-Beh\u00e7et disease.<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-causa-la-enfermedad-de-Behcet\"><\/span>What causes Beh\u00e7et&#039;s disease?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The cause of Beh\u00e7et&#039;s disease is unknown, but it is presumed to be a <span class=\"term\" data-term-id=\"691\">autoimmune<\/span> disorder: an individual&#039;s immune system begins to react against his tissues. The reason for this remains a mystery, but it is possible. <span class=\"term\" data-term-id=\"937\">bacterial<\/span> or viral <span class=\"term\" data-term-id=\"145\">infection<\/span> may have a role in their development.<\/p>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQuien-esta-en-riesgo-de-contraer-la-enfermedad-de-Behcet\"><\/span>Who is at risk for Beh\u00e7et&#039;s disease?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Beh\u00e7et&#039;s disease is the most common and most serious in people with lineages of the Silk Road. The countries of the Silk Road include those of the Mediterranean basin, the Middle East and the Far East; the <span class=\"term\" data-term-id=\"578\">incidence<\/span> it is around 1 in 10,000 people. However, Beh\u00e7et&#039;s disease is seen all over the world, even in those of other ethnic heritage; In the US, the incidence is reported to be 1 in 20,000.<\/p>\n<p>In people of Silk Road descent, Beh\u00e7et&#039;s disease is more common in men than in women. However, the trend is reversed with more women than men affected in people of other ethnic origins. The disease can develop at any age, but it is most common when people reach their 20s.<span>&#8211;<\/span>30 years.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCuales-son-los-signos-y-sintomas-de-la-enfermedad-de-Behcet\"><\/span>What are the signs and symptoms of Beh\u00e7et&#039;s disease?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Mouth ulcers (aphthous ulcers) are the most common and the earliest. <span class=\"term\" data-term-id=\"899\">sign<\/span> of Beh\u00e7et&#039;s disease. However, before they appear, a patient may experience a variety of <span class=\"term\" data-term-id=\"805\">recurrent<\/span> Signs and symptoms including:<\/p>\n<ul>\n<li>Sore throat and tonsillitis.<\/li>\n<li>Muscle and joint pain<\/li>\n<li>\n<span class=\"term\" data-term-id=\"1211\">Discomfort<\/span>, <span class=\"term\" data-term-id=\"308\">generalized<\/span> weakness<\/li>\n<li>Anorexia, weight loss.<\/li>\n<li>Headache<\/li>\n<li>Fluctuations in body temperature.<\/li>\n<\/ul>\n<p>Painful mouth ulcers are usually the first outward sign of Beh\u00e7et&#039;s disease and occur in approximately 70% of patients. Ulcers can occur anywhere in the mouth, including on the tongue and inside the lips and cheeks. They usually last 1 to 2 weeks, but can last up to three weeks.<\/p>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Enfermedad-de-Behcet\"><\/span>Behcet&#039;s disease<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='lip-ulcer__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-8616169-5495785' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/lip-ulcer__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-8616169.jpg'>\n<\/div>\n<p class=\"p-small\">Lip ulcer<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='behcetsusp__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildm2xq-6374104-2472724' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/behcetsusp__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDM2XQ-6374104.jpg'>\n<\/div>\n<p class=\"p-small\">Lip ulcer<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='pathergy__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-4656147-5208270' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/pathergy__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-4656147.jpg'>\n<\/div>\n<p class=\"p-small\">Pathergy<\/p>\n<\/p><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<p>See images of vulvar ulcers.<\/p>\n<p>Other common signs and symptoms indicative of Beh\u00e7et&#039;s disease include:<\/p>\n<ul>\n<li>\n<strong>Genital ulcers<\/strong>: These aphthous ulcers occur less frequently than canker sores. They are painful and generally heal with scars. They are not genital herpes, which is caused by the herpes virus.<\/li>\n<li>\n<strong>Ocular involvement<\/strong>: <span class=\"term\" data-term-id=\"505\">uveitis<\/span>, which can redden and swell the eye tissue, can occur. The retina can sometimes be affected and, if left untreated, can lead to blindness.<\/li>\n<li>\n<strong>Skin lesions<\/strong>painful <span class=\"term\" data-term-id=\"367\">nodules<\/span> since <span class=\"term\" data-term-id=\"90\">erythema<\/span> nodoso are common. Patients may also have acne-like sores that occur on the arms, legs, and trunk.<\/li>\n<\/ul>\n<p>Less common symptoms include gastrointestinal problems (eg, abdominal pain, diarrhea, vomiting), joint pain and swelling, nervous system problems, and <span class=\"term\" data-term-id=\"1068\">blood vessel<\/span> and circulation problems.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFComo-se-diagnostica-la-enfermedad-de-Behcet\"><\/span>How is Beh\u00e7et&#039;s disease diagnosed?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Beh\u00e7et&#039;s disease can be difficult to diagnose as signs and symptoms come and go and may not be apparent at one time. If you have a history of recurring mouth and genital ulcers, uveitis, and skin sores, this is indicative of the condition.<\/p>\n<p>The international criteria for the classification of Beh\u00e7et&#039;s disease define the conditions as:<\/p>\n<p>At least three episodes of recurrent oral ulcers in 12 months plus at least two more of the following:<\/p>\n<ul>\n<li>Genital ulcers<\/li>\n<li>Ocular involvement (uveitis or retinal damage)<\/li>\n<li>Skin lesions<\/li>\n<li>\n<p>Positive <span class=\"term\" data-term-id=\"225\">pathergy<\/span> test (this is a skin prick test that can confirm Beh\u00e7et&#039;s disease)<\/li>\n<\/ul>\n<p>There are no specific tests to confirm the diagnosis, but screening investigations such as blood count, kidney and liver function tests, and <span class=\"term\" data-term-id=\"946\">C-reactive protein<\/span> It can be done to determine which organs are affected by the condition.<\/p>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCual-es-el-tratamiento-para-la-enfermedad-de-Behcet\"><\/span>What is the treatment for Beh\u00e7et&#039;s disease?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Currently, there is no cure for Beh\u00e7et&#039;s disease. The main goal is to treat and control the symptoms so that complications do not develop. Because Beh\u00e7et&#039;s disease affects many different parts of the body, a team of doctors from various specialties will treat most people.<\/p>\n<p>Some medications that can help control symptoms include:<\/p>\n<p><strong><span class=\"term\" data-term-id=\"1330\">Current<\/span> therapy<\/strong><\/p>\n<ul>\n<li>\n<p>Tetracycline <span class=\"term\" data-term-id=\"1119\">solution<\/span>\n<\/li>\n<li>Topical corticosteroids<\/li>\n<li>Local anesthetics<\/li>\n<\/ul>\n<p><strong><span class=\"term\" data-term-id=\"380\">Systemic<\/span> therapy<\/strong><\/p>\n<ul>\n<li>Oral corticosteroids\n<\/li>\n<li>Nonsteroidal anti-steroids<span class=\"term\" data-term-id=\"490\">inflammatory<\/span> medications (eg, aspirin, ibuprofen)<\/li>\n<li>Immunosuppressants (eg, Azathioprine, chlorambucil)<\/li>\n<li>Experimental and investigational drugs (for example, colchicine, cyclophosphamide, thalidomide, infliximab, and potassium iodide)<\/li>\n<li>\n<p>Apremilast, which has been approved by the Food and Drug Administration (FDA) in the US for oral ulcers in Beh\u00e7et&#039;s disease<\/li>\n<li>A biological agent such as the TNF-alpha inhibitor, adalimumab.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Cual-es-el-pronostico\"><\/span>Which is the <span class=\"term\" data-term-id=\"241\">forecast<\/span>?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Beh\u00e7et&#039;s disease is a <span class=\"term\" data-term-id=\"319\">chronic<\/span> disease where the <span class=\"term\" data-term-id=\"349\">acute<\/span> The phases come and go with varying degrees of intensity. In the early stages of the disease, attacks can be frequent and last for several weeks. As time passes, the intervals between attacks may become longer and, in some cases, the attacks stop completely. The disease is then considered to be in <span class=\"term\" data-term-id=\"1260\">remission<\/span> but he can hit again at any time.<\/p>\n<p>Death occurs in approximately 4% of Beh\u00e7et cases. Causes of mortality are attributed to gastrointestinal <span class=\"term\" data-term-id=\"1431\">drilling<\/span>, central nervous system involvement and <span class=\"term\" data-term-id=\"753\">vascular<\/span> aneurysms (swelling of <span class=\"term\" data-term-id=\"953\">blood vessels<\/span>)<\/p>\n<p>Most of Beh\u00e7et&#039;s patients live full lives, although they will most likely deal with some level of symptoms during this time.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>\u00bfQu\u00e9 es la enfermedad de Beh\u00e7et? Enfermedad de Beh\u00e7et (o s\u00edndrome) es una enfermedad rara caracterizada por dolor en la boca \u00falceras, \u00falceras genitales, problemas oculares y lesiones cut\u00e1neas. La&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-6800","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6800","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=6800"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6800\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=6800"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=6800"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=6800"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}