<\/span><\/h2>\nMost adverse cutaneous<\/span> the events associated with vaccines are caused by a normal inflammatory<\/span> response to a foreign substance. Since these inflammatory reactions are not related to allergy<\/span>, most patients can safely receive subsequent vaccinations. A less common cause of an adverse skin reaction is an allergy to a vaccine or one of its components.<\/p>\n<\/span>Inflammatory skin reactions.<\/span><\/h2>\n\n\n\n| Vaccination\/Constitution<\/span>\n<\/th>\n | Reaction<\/th>\n | Why<\/th>\n<\/tr>\n |
\n| Most vaccines<\/td>\n | Local reactions at the injection site, such as swelling, redness, and \/ or pain can occur with up to 80% of vaccine doses, depending on the type of vaccine. Local reactions generally occur within a few hours of the injection, are generally mild, and do not require any specific treatment.<\/td>\n | The normal inflammatory response to a foreign substance.<\/td>\n<\/tr>\n |
\n| Measles, Mumps, and Rubella (MMR) Vaccine<\/td>\n | Transient eruption<\/span> in up to 5% of the recipients.<\/td>\n | Since the vaccine contains live viruses, it is probably due to the modified measles induced by the vaccine.<\/td>\n<\/tr>\n |
\n| Chickenpox vaccine<\/td>\n | \n Chickenpox lesions can appear at the injection site in approximately 3% of recipients. In another 3%, the lesions may be more generalized<\/span>. A zoster-like rash can rarely appear after the chickenpox vaccine.<\/td>\n | Another live virus vaccine that can cause vaccine-induced illness.<\/td>\n<\/tr>\n |
\n| Tetanus and diphtheria toxoids<\/td>\n | \nHypersensitivity<\/span> (sometimes called Arthus-type reaction): rare and severe local reaction (swelling, redness, pain). Not allergic<\/td>\n | It is believed to be due to the very high concentration of antibody<\/span>, usually caused by too many doses of toxoid.<\/td>\n<\/tr>\n\n| Aluminum hydroxide<\/td>\n | Induces subcutaneous<\/span> nodules<\/span> (small lumps under the skin) in up to 19% of patients. The nodules usually resolve within a few months. Not allergic<\/td>\n | Non-specific reaction to a foreign substance.<\/td>\n<\/tr>\n | \n| Tetanus and diphtheria toxoids<\/td>\n | Generalized urticaria<\/span> (urticaria), angioedema<\/span>, and unidentified eruptions in about 5 to 13% of the recipients.<\/td>\n | Studies suggest that most mild to moderate generalized reactions result from nonspecific activation of the inflammatory system by high doses of bacterial<\/span> components. Subsequent booster injections of suspect vaccines are well tolerated.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n \n \n \n<\/div><\/div><\/div><\/div>\n | |