<\/span><\/h2>\nAlbinism is a condition in which people have little or no melanin<\/span> pigment<\/span> (compound that creates color) in your eyes, skin or hair<\/span>. Because of this, people with albinism look a little different from other members of their family without albinism. They have very light skin, which is prone to sunburn, their hair is white or a very light color, and they can squint a lot since their eyes are sensitive to sunlight.<\/p>\n<\/span>Classification of albinism.<\/span><\/h2>\nThere are two main categories of albinism: oculocutaneous and ocular<\/span> albinism.<\/p>\nOculocutaneous<\/p>\n
\n- It involves dilution of hair, skin and eye color.<\/li>\n
- The most common form of albinism.<\/li>\n<\/ul>\n
Ocular<\/p>\n
\n- Melanin pigment is missing mainly in the eyes, while skin and hair appear normal or only slightly lighter<\/li>\n
- It represents 10-15% of all cases of albinism.<\/li>\n<\/ul>\n
Oculocutaneous albinism (OCA) forms a group of different types of albinism based on specific albinism gene<\/span> involved. Oculocutaneous albinism type 1 and type 2 are the most common types of oculocutaneous albinism.<\/p>\nOCA 1A<\/p>\n
\n- Absent tyrosinase<\/span> exercise<\/li>\n
- Eyes: bluish gray, reduced visual acuity<\/li>\n
- Hair: white at birth, may turn yellow over time<\/li>\n
- Skin: white, moles are notpigmented<\/span>\n<\/li>\n<\/ul>\n
OCA 1B<\/p>\n
\n- Reduced tyrosinase activity<\/li>\n
- Variable dilution of skin and hair pigment.<\/li>\n
- Temperature sensitive subtype<\/li>\n<\/ul>\n
OCA 2OCA 2 mutation<\/span> (formerly P gene)<\/p>\n\n- Variable dilution of skin and hair pigment.<\/li>\n
- Over time, develop solar lentigines<\/span> on the sunexposed skin<\/span>\n<\/li>\n
- Prader-Willi and Angelman Associates (chromosome<\/span> 15)<\/li>\n<\/ul>\n
OCA 3TYRP 1 mutation<\/p>\n