{"id":6969,"date":"2020-04-23T22:59:37","date_gmt":"2020-04-24T01:59:37","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/angiosarcoma-2\/"},"modified":"2020-04-27T16:37:13","modified_gmt":"2020-04-27T19:37:13","slug":"angiosarcoma-2","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/angiosarcoma-2\/","title":{"rendered":"Angiosarcoma"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/angiosarcoma-2\/#%C2%BFQue-es-un-angiosarcoma\" >What is an angiosarcoma?<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/angiosarcoma-2\/#Angiosarcoma\" >Angiosarcoma<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/angiosarcoma-2\/#%C2%BFQuien-contrae-angiosarcoma\" >Who gets angiosarcoma?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/angiosarcoma-2\/#%C2%BFQue-causa-el-angiosarcoma\" >What causes angiosarcoma?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/angiosarcoma-2\/#Angiosarcoma-cutaneo\" >Cutaneous angiosarcoma<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/angiosarcoma-2\/#%C2%BFCual-es-el-tratamiento-del-angiosarcoma\" >What is the treatment of angiosarcoma?<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-es-un-angiosarcoma\"><\/span>What is an angiosarcoma?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Angiosarcoma is a rare and aggressive disorder. <span class=\"term\" data-term-id=\"176\">evil one<\/span> <span class=\"term\" data-term-id=\"289\">tumor<\/span> (<span class=\"term\" data-term-id=\"30\">Cancer<\/span>) that arises from <span class=\"term\" data-term-id=\"758\">endothelial<\/span> cells, which normally line the walls of blood or <span class=\"term\" data-term-id=\"744\">lymphatic<\/span> glasses<\/p>\n<ul>\n<li>Hemangiosarcomas begin in <span class=\"term\" data-term-id=\"1068\">blood vessel<\/span> walls<\/li>\n<li>Lymphangiosarcomas begin on the walls of the lymphatic vessels.<\/li>\n<\/ul>\n<p>Angiosarcomas can occur in any organ of the body, but are most often found on the skin and <span class=\"term\" data-term-id=\"1183\">Soft fabric<\/span>. They can also originate in the liver, breasts, spleen, bones, or heart.<\/p>\n<p>After having been surgically removed, angiosarcomas:<\/p>\n<ul>\n<li>Often repeated locally<\/li>\n<li>Systemic spread, with a high rate of <span class=\"term\" data-term-id=\"1774\">lymph node<\/span> <span class=\"term\" data-term-id=\"383\">metastasis<\/span>\n<\/li>\n<li>Have a poor <span class=\"term\" data-term-id=\"241\">forecast<\/span> and a high mortality rate.  <\/li>\n<\/ul>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Angiosarcoma\"><\/span>Angiosarcoma<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='angiosarcoma1__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildg1xq-3310114-7480151' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/angiosarcoma1__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDg1XQ-3310114.jpg'>\n<\/div>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='angiosarcoma2__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-5624812-2488176' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/angiosarcoma2__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-5624812.jpg'>\n<\/div><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQuien-contrae-angiosarcoma\"><\/span>Who gets angiosarcoma?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Angiosarcoma is twice as common in men as in women. Angiosarcoma of the head and neck mainly affects older people.<\/p>\n<p>The tumor may develop as a complication of a pre-existing condition. Certain groups of patients may be at increased risk of developing angiosarcomas. These include:<\/p>\n<ul>\n<li>Patients with <span class=\"term\" data-term-id=\"319\">chronic<\/span> lymphedema (a buildup of lymph fluid in the arms) who underwent a radical mastectomy for breast cancer (removal of the breast and all <span class=\"term\" data-term-id=\"1775\">lymph nodes<\/span> under the arm)<\/li>\n<li>\n<span class=\"term\" data-term-id=\"1325\">Radiotherapy<\/span> patients (especially those who have been exposed to the Thorotrast radiation-emitting contrast agent; this agent is no longer used, but angiosarcomas have occurred in people decades after exposure)<\/li>\n<li>Patients with foreign material (such as Dacron, shrapnel, steel, and plastic) in the body.<\/li>\n<li>Patients exposed to environmental agents such as aerosols containing arsenic and vinyl chloride used in the plastics industry.<\/li>\n<\/ul>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-causa-el-angiosarcoma\"><\/span>What causes angiosarcoma?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The cause of the fast <span class=\"term\" data-term-id=\"893\">proliferation<\/span> and <span class=\"term\" data-term-id=\"543\">infiltration<\/span> of malignant endothelial cells in angiosarcoma is generally unknown. <\/p>\n<p>What are the signs and symptoms of angiosarcoma?<\/p>\n<p>The signs and symptoms of angiosarcoma differ depending on the location of the tumor. Often, the symptoms of the disease are not apparent until the tumor has become more advanced.<\/p>\n<p>Soft tissue symptoms include:<\/p>\n<ul>\n<li>Rapidly growing tumor of the limbs or abdomen.<\/li>\n<li>Abdominal tumors can grow to large sizes before they are detected since the abdomen can accommodate tumors<\/li>\n<li>\n<span class=\"term\" data-term-id=\"120\">Hemorrhage<\/span>, <span class=\"term\" data-term-id=\"598\">anemia<\/span>, <span class=\"term\" data-term-id=\"118\">hematoma<\/span>and gastrointestinal bleeding<\/li>\n<li>Enlarged <span class=\"term\" data-term-id=\"1351\">adjacent<\/span> lymph nodes<\/li>\n<\/ul>\n<p>Symptoms present on the skin include:<\/p>\n<ul>\n<li>Enlarged bruise, a blue-black <span class=\"term\" data-term-id=\"198\">nodule<\/span>or uncured <span class=\"term\" data-term-id=\"1278\">ulceration<\/span>\n<\/li>\n<li>The injuries can bleed and be painful.<\/li>\n<li>Angiosarcomas that occur in the head and neck in older people are one of the most common forms of <span class=\"term\" data-term-id=\"47\">cutaneous<\/span> angiosarcoma<\/li>\n<\/ul>\n<p>Angiosarcoma can also affect the bones as well. <\/p>\n<ul>\n<li>Tumors can grow in multiple bones in the same limb.<\/li>\n<li>Pain and tenderness in the affected area are common.<\/li>\n<li>There may be swelling and enlargement of the affected limb.<\/li>\n<\/ul>\n<p>Angiosarcoma in the breast presents as a <span class=\"term\" data-term-id=\"1171\">palpable<\/span> dough without tenderness. Tumors often grow deep within the breast tissue, causing <span class=\"term\" data-term-id=\"1769\">diffuse<\/span> enlarged breasts with associated bluish skin discoloration. <\/p>\n<p><span class=\"term\" data-term-id=\"1105\">Hepatic<\/span> The symptoms of angiosarcoma can vary and are not specific, and can include fatigue, weight loss, and pain in the right upper quadrant. Angiosarcoma in the lungs can cause bloody chest pain <span class=\"term\" data-term-id=\"1874\">sputum<\/span>, weight loss, cough and shortness of breath<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Angiosarcoma-cutaneo\"><\/span>Cutaneous angiosarcoma<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Cutaneous angiosarcoma is the most common form of angiosarcoma not associated with chronic lymphedema. The disease is located mainly in the head and neck of older people and is also known as Wilson-Jones angiosarcoma, senile angiosarcoma, or malignant angioendothelioma.<\/p>\n<p>The clinical features of this form of angiosarcoma are lesions, which appear most frequently on the scalp or upper forehead.<\/p>\n<ul>\n<li>In the early stages of the disease, the lesions may be singular or multifocal, bright red or dark slow-spreading patches, somewhat like a poorly defined hematoma.<\/li>\n<li>Injuries can become high <span class=\"term\" data-term-id=\"367\">nodules<\/span> or <span class=\"term\" data-term-id=\"368\">plates<\/span> It can bleed and ulcerate.<\/li>\n<li>Lesions grow rapidly and spread, making margins difficult to define.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCual-es-el-tratamiento-del-angiosarcoma\"><\/span>What is the treatment of angiosarcoma?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The treatment of angiosarcoma is <span class=\"term\" data-term-id=\"1179\">dependent<\/span> on the location of angiosarcoma and the extent of the tumor. Treatment includes <span class=\"term\" data-term-id=\"1619\">chemotherapy<\/span>, surgery, radiotherapy or a combination of these treatment modalities.<\/p>\n<p>The optimal treatment of cutaneous angiosarcoma has not been defined. These angiosarcomas are difficult to treat due to their multifocal nature and extensive spread pattern. Radical surgery and postoperative radiation therapy are generally used but the tumor <span class=\"term\" data-term-id=\"1074\">reappearance<\/span> It is common after treatment. Despite aggressive treatment, the prognosis is often poor.<\/p>\n<p><span>Paclitaxel is a powerful antiangiogenic drug that shows promise in the treatment of angiosarcoma when administered weekly.<\/span><\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>\u00bfQu\u00e9 es un angiosarcoma? El angiosarcoma es un trastorno poco frecuente y agresivo. maligno tumor (c\u00e1ncer) que surge de endotelial c\u00e9lulas, que normalmente recubren las paredes de sangre o linf\u00e1tico&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-6969","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6969","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=6969"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6969\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=6969"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=6969"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=6969"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}