{"id":6996,"date":"2020-04-24T01:50:13","date_gmt":"2020-04-24T04:50:13","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/antibioticos-2\/"},"modified":"2020-04-27T16:34:36","modified_gmt":"2020-04-27T19:34:36","slug":"antibiotics-2","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/antibioticos-2\/","title":{"rendered":"Antibiotics"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/antibioticos-2\/#%C2%BFQue-son-los-antibioticos\" >What are antibiotics?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/antibioticos-2\/#Historia-de-antibioticos\" >History of antibiotics.<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/antibioticos-2\/#Clasificacion-de-antibioticos\" >Classification of antibiotics.<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/antibioticos-2\/#Usos-de-antibioticos\" >Uses of antibiotics.<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/antibioticos-2\/#Resistencia-antibiotica\" >antibiotic resistance<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/antibioticos-2\/#Efectos-secundarios-de-los-antibioticos\" >Side effects of antibiotics.<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-son-los-antibioticos\"><\/span>What are antibiotics?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Antibiotics are chemical compounds used to kill or <span class=\"term\" data-term-id=\"1022\">inhibit<\/span> The growth of <span class=\"term\" data-term-id=\"935\">bacteria<\/span>. Strictly speaking, antibiotics are a subgroup of organic anti-infective agents that are derived from bacteria or molds that are <span class=\"term\" data-term-id=\"1159\">toxic<\/span> to other bacteria. However, the term antibiotic is now used loosely to include anti-infectives produced from synthetic and semi-synthetic compounds.<\/p>\n<p>The term antibiotic can be used interchangeably with the term antibacterial. However, it is incorrect to use the term antibiotic when referring to <span class=\"term\" data-term-id=\"1512\">antiviral<\/span>, antiprotozoal and antifungal.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Historia-de-antibioticos\"><\/span>History of antibiotics.<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Penicillin was the first antibiotic used successfully in treatment. <span class=\"term\" data-term-id=\"937\">bacterial<\/span> infections Sir Alexander Fleming first discovered it in 1928, but its potential for treating infections was not recognized until more than a decade later, when Ernst B Chain, Sir Howard Florey and Norman Heatley produced enough purified penicillin to treat patients. In the 1950s, a large number of antibiotics were discovered and manufactured for the treatment of diseases caused by bacterial infection. Over the past 50 years, antibiotics have transformed patterns of illness and death.<\/p>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Clasificacion-de-antibioticos\"><\/span>Classification of antibiotics.<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Antibiotics can be classified in several ways. The most common method classifies them according to their chemical structure, since antibiotics that share the same or a similar chemical structure generally show similar patterns of antibacterial activity, effectiveness, <span class=\"term\" data-term-id=\"1160\">toxicity<\/span> and allergic potential.<\/p>\n<p>B-lactam antibiotics inhibit the synthesis of the bacterial cell wall. They include:<\/p>\n<ul>\n<li>Penicillins<\/li>\n<li>Cephalosporins<\/li>\n<li>Carbapenems<\/li>\n<\/ul>\n<p>Penicillins<\/p>\n<ul>\n<li>Penicillin G<\/li>\n<li>Amoxicillin<\/li>\n<li>Flucloxacillin<\/li>\n<\/ul>\n<p>Cephalosporins<\/p>\n<ul>\n<li>Cefoxitin<\/li>\n<li>Cefotaxime<\/li>\n<li>Ceftriaxone<\/li>\n<\/ul>\n<p>Carbapenem<\/p>\n<ul>\n<li>Imipenem<\/li>\n<\/ul>\n<p>Macrolides inhibit bacterial protein synthesis.  <\/p>\n<ul>\n<li>Erythromycin<\/li>\n<li>Azithromycin<\/li>\n<li>Clarithromycin<\/li>\n<\/ul>\n<p>Tetracyclines inhibit bacterial protein synthesis.  <\/p>\n<ul>\n<li>Tetracycline<\/li>\n<li>Minocycline<\/li>\n<li>Doxycycline<\/li>\n<li>Lymecycline<\/li>\n<\/ul>\n<p>Fluoroquinolones inhibit bacteria <span class=\"term\" data-term-id=\"1296\">DNA<\/span> synthesis. <\/p>\n<ul>\n<li>Norfloxacin<\/li>\n<li>Ciprofloxacin<\/li>\n<li>Enoxacin<\/li>\n<li>Ofloxacin<\/li>\n<\/ul>\n<p>Sulfonamides block bacterial cells <span class=\"term\" data-term-id=\"934\">metabolism<\/span> inhibiting <span class=\"term\" data-term-id=\"1526\">enzymes<\/span>. <\/p>\n<ul>\n<li><span>Trimethoprim + sulfamethoxazole<\/span><\/li>\n<\/ul>\n<p><span class=\"term\" data-term-id=\"1012\">Aminoglycosides<\/span> inhibit bacterial protein synthesis. <\/p>\n<ul>\n<li>Gentamicin<\/li>\n<li>Amikacin<\/li>\n<\/ul>\n<p>Imidazole antibiotics inhibit bacterial DNA synthesis.  <\/p>\n<ul>\n<li>Metronidazole<\/li>\n<\/ul>\n<p><span class=\"term\" data-term-id=\"1733\">Peptides<\/span> inhibit the synthesis of the bacterial cell wall.  <\/p>\n<ul>\n<li>Bacitracin<\/li>\n<\/ul>\n<p>Lincosamides inhibit bacterial protein synthesis.<\/p>\n<ul>\n<li>Clindamycin<\/li>\n<li>Lincomycin<\/li>\n<\/ul>\n<p>The following medications inhibit bacterial protein synthesis.<\/p>\n<ul>\n<li>Fusidic acid<\/li>\n<li>Mupirocin<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Usos-de-antibioticos\"><\/span>Uses of antibiotics.<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Antibiotics only work against infections caused by bacteria. Bacterial infections are much less common than viral infections. Most coughs and colds are viral in origin, so antibiotics should not be prescribed for these. Antibiotics should only be used when absolutely necessary, because:<\/p>\n<ul>\n<li>There is a growing resistance of bacteria to treatment.<\/li>\n<li>Resistant bacteria are selected through the use of antibiotics.<\/li>\n<li>Antibiotics can have serious side effects in some people.<\/li>\n<\/ul>\n<p>Some common bacterial infections that require antibiotic therapy include:<\/p>\n<ul>\n<li>\n<p>Staphylococcal skin infections, for example impetigo (school sores)<\/li>\n<li>\n<p>Streptococcal skin infections, eg cellulitis.\n<\/li>\n<li>A little ear and <span class=\"term\" data-term-id=\"267\">breast<\/span> infections<\/li>\n<li>&#039;Streptococcus&#039; \u2013 sore throat caused by <em>Streptococcus<\/em>\n<\/li>\n<\/ul>\n<p>If these infections are left untreated, the resulting illness can be serious and even fatal.<\/p>\n<p>In severe bacterial infections where patients may be hospitalized, a broad-spectrum intravenous antibiotic (one that is active against many different bacteria) is often given to begin treatment. As soon as laboratory tests confirm the infecting bacteria, the antibiotic should be changed to one that is active against specific bacteria. After 48 hours of intravenous treatment, if there is clinical improvement, the patient can be switched to an oral form of the antibiotic.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Resistencia-antibiotica\"><\/span>antibiotic resistance<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Overuse and inappropriate use of antibiotics has led to antibiotic resistance. Bacteria that were once susceptible to antibiotics have developed ways to survive drugs meant to kill or weaken them. This is also known as antibacterial resistance or drug resistance. Some diseases such as tuberculosis, gonorrhea, and childhood bacterial ear infections, which were once easily treated with antibiotics, are now becoming difficult to treat as the bacteria have become resistant to these medications. About 70% of the bacteria that cause infections in hospitals are resistant to at least one of the antibiotics most commonly used to treat infections. Methicillin (methicillin) resistant <em>Staphylococcus aureus<\/em> (MRSA) is a particular problem for patients with skin diseases, <span class=\"term\" data-term-id=\"1279\">ulcers<\/span> and surgical wounds.<\/p>\n<p>Doctor&#039;s responsibility<\/p>\n<ul>\n<li>Only prescribe antibiotics if they are bacterial <span class=\"term\" data-term-id=\"145\">infection<\/span> present<\/li>\n<li>Prescribe at approved dosage and duration or as recommended by experts<\/li>\n<li>Educate the patient about the importance of completing their course of antibiotics as directed.<\/li>\n<\/ul>\n<p>Patient Responsibility<\/p>\n<ul>\n<li>Understand that not all infections are bacterial and that not all bacterial infections will go away with antibiotics (eg, folliculitis)<\/li>\n<li>Take antibiotics exactly as directed (i.e., with or without food, etc.)<\/li>\n<li>Be sure to finish the course of antibiotics.<\/li>\n<\/ul>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Efectos-secundarios-de-los-antibioticos\"><\/span>Side effects of antibiotics.<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Antibiotics are associated with many side effects, including <span class=\"term\" data-term-id=\"47\">cutaneous<\/span> <span class=\"term\" data-term-id=\"1333\">Adverse reactions<\/span>. Some side effects are class related, but most reactions are specific to the agent in that individual.<\/p>\n<p>Here are some common problems with antibiotics:<\/p>\n<ul>\n<li>\n<span class=\"term\" data-term-id=\"1136\">Allergy<\/span> to certain antibiotics or classes of antibiotics (eg, allergy to penicillin)<\/li>\n<li>Many antibiotics cause gastrointestinal problems (eg, diarrhea, vomiting, nausea).<\/li>\n<li>Antibiotics kill not only their targets, but also others<span class=\"term\" data-term-id=\"883\">organisms<\/span> that live in and on our body (flora) to prevent other diseases (e.g. oral and\/or vaginal thrush)<\/li>\n<li>A variety of skin rashes may occur, which can be mild (e.g., hives) or devastating (e.g., toxic). <span class=\"term\" data-term-id=\"846\">epidermal<\/span> necrolysis).<\/li>\n<\/ul>\n<div class=\"grey-box\"><em><span style=\"font-size: 0.9em;\">New Zealand approved data sheets are the official source of information for these prescription drugs, including approved uses and risk information. See the New Zealand individual data sheet on the Medsafe website.<\/span><\/em><\/div>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>\u00bfQu\u00e9 son los antibi\u00f3ticos? Los antibi\u00f3ticos son compuestos qu\u00edmicos utilizados para matar o inhibir el crecimiento de bacterias. Estrictamente hablando, los antibi\u00f3ticos son un subgrupo de agentes antiinfecciosos org\u00e1nicos que&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-6996","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6996","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=6996"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/6996\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=6996"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=6996"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=6996"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}