<\/span><\/h2>\nAtypical fibroxanthoma (AFX) is a dermal<\/span> spindle cell<\/span> tumor<\/span> It usually occurs on the head and neck of sun damaged older people. Tumor growth should be considered a skin type. Cancer<\/span> but can behave in a benign<\/span> Fashion.<\/p>\nA rare type of atypical fibroxanthoma occurs in younger patients on parts of the body that are not normally overexposed to the sun. These tumors are usually found on the trunk and extremities and tend to be larger and slower growing.<\/p>\n\n<\/span>Atypical fibroxanthoma<\/span><\/h5>\n<\/section>\n\n\n
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Atypical fibroxanthoma<\/p>\n
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Atypical fibroxanthoma<\/p>\n
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Atypical fibroxanthoma<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>What causes atypical fibroxanthoma?<\/span><\/h2>\nThe development of atypical fibroxanthomas is associated with aging, sun exposure (Ultraviolet radiation<\/span>) and\/or ionizing radiation (X-rays). Both forms of radiation can cause abnormal growth of atypicals. spindle cells<\/span>. They are believed to come from fibrous cells in the dermis<\/span> or of epidermal<\/span> keratinocytes<\/span>.<\/p>\n\n
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<\/span>Who gets atypical fibroxanthoma?<\/span><\/h2>\nReports have shown an increase incidence<\/span> of atypical fibroxanthoma in patients with acquired immunodeficiency syndrome<\/span> (AIDS) and in immunocompromised patients, for example due to an organ transplant<\/span>.<\/p>\nAtypical fibroxanthoma affects both sexes equally, with a mean age of 69 years at the time of diagnosis.<\/p>\n
<\/span>What are the clinical characteristics of atypical fibroxanthoma?<\/span><\/h2>\nAtypical fibroxanthoma often appears in areas that have received excessive sun exposure, usually around the scalp, ears, nose, cheeks, and back of the neck, or in areas where people may have previously received radiotherapy<\/span> treatment. They have also been reported to occur on the trunk, extremities, and in areas protected from the sun.<\/p>\n\n- A solitary tumor or multiple tumors may occur.<\/li>\n
- Typically, AFX is a red, juicy, dome-shaped nodule<\/span> which may be bleeding, ulcerated or crusted.<\/li>\n
- The tumor begins as a small nodule that grows rapidly over 6 months to a size of approximately 2-3 cm. <\/li>\n
- Four times more tumors are diagnosed in the head and neck than in other sites of the body.<\/li>\n<\/ul>\n
Although it's strange cutaneous<\/span> metastasis<\/span> of atypical fibroxanthoma have been reported. <\/p>\n<\/span>How is atypical fibroxanthoma diagnosed?<\/span><\/h2>\nBecause atypical fibroxanthoma can look like other types of skin cancer, it is usually diagnosed by a pathologist<\/span> after a skin biopsy<\/span> or excision<\/span>. <\/p>\nThe diagnosis depends on finding large, pleomorphic<\/span>, fibrocytic, spindle-shaped, anaplastic<\/span> Tumor cells arranged randomly in the dermis. Immunohistochemistry<\/span> Staining should be done, but may be nonspecific. Cytokeratin<\/span> and melanoma<\/span> The stains are negative.<\/span><\/p>\nDermoscopic features may resemble those of basal<\/span> cell carcinoma<\/span> or scaly<\/span> cell carcinoma<\/span><\/p>\n\n<\/span>Macro atypical fibroxanthoma + dermoscopy<\/span><\/h5>\n<\/section>\n\n\n
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Macro view of histologically confirmed atypical fibroxanthoma<\/p>\n
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Dermatoscopy view of histologically confirmed atypical fibroxanthoma<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>Which is the differential diagnosis<\/span> for atypical fibroxanthoma?<\/span><\/h2>\nOther injuries to consider in the differential include:<\/p>\n
\n- \nPyogenic<\/span> granuloma<\/span> <\/li>\n
- \nSpindle cell<\/span> squamous cell carcinoma\n<\/li>\n
- Spindle cell melanoma\n<\/li>\n
- Superficial portion of a evil one<\/span> fibrous histiocytoma<\/li>\n
- \nLeiomyosarcoma<\/span>.<\/li>\n<\/ul>\n
<\/span>What is the treatment of atypical fibroxanthoma?<\/span><\/h2>\nAtypical fibroxanthoma is treated by complete surgical excision. Small lesions can be removed by curettage. Mohs micrographic surgery is becoming the treatment of choice for large or recurrent<\/span> lesions, as it reliably removes the entire tumor while sparing the normal healthy tissue surrounding it. <\/p>\n<\/span>What is the outcome for atypical fibroxanthoma?<\/span><\/h2>\nAtypical fibroxanthoma rarely recurs after complete excision with clear margins. Reappearance<\/span> and metastasis<\/span> are more likely in people who are immunosuppressed<\/span>.<\/p>\n<\/span>How is atypical fibroxanthoma prevented?<\/span><\/h2>\nMost cases of atypical fibroxanthoma could be prevented by avoiding excessive sun exposure. Patients are advised to follow sun protection methods when outdoors.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"
Que es at\u00edpico fibroxantoma? El fibroxantoma at\u00edpico (AFX) es un d\u00e9rmico c\u00e9lula de huso tumor que generalmente ocurre en la cabeza y el cuello del sol da\u00f1\u00f3 a las personas…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-7394","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7394","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=7394"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7394\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=7394"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=7394"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=7394"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}