<\/span><\/h2>\nGold compounds should only be used by a doctor experienced in their use, as there is a risk of toxicity<\/span> It is high and the side effects are potentially dangerous. It is essential that treatment with the drug is no more disabling than the disease for which it is being treated.<\/p>\nBefore starting treatment with gold compounds, a routine base<\/span> The evaluation must include:<\/p>\n\n- complete blood cell count<\/li>\n
- \nrenal<\/span> function tests<\/li>\n
- liver function tests<\/li>\n<\/ul>\n
Regular monitoring of these should continue throughout the treatment.<\/p>\n
Doses similar to those used to treat rheumatoid arthritis are given. If there is no improvement by the time the total dose reaches 1 g, treatment should be discontinued.<\/p>\n
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<\/span>\nContraindications<\/span> to gold<\/span><\/h2>\nGold compounds should not be used in the following circumstances:<\/p>\n
\n- \nProgressive<\/span> renal disease<\/li>\n
- Severe asset hepatic<\/span> disease<\/li>\n
- History of hypersensitivity<\/span> to gold compounds<\/li>\n<\/ul>\n
<\/span>Precautions when prescribing gold<\/span><\/h2>\nBefore starting treatment with gold compounds, the following should be considered:<\/p>\n
\n- \nAllergies<\/span> to any medicine, particularly any unusual or allergic reaction<\/span> to gold or other metals<\/li>\n
- The pregnancy<\/li>\n
- Breast-feeding<\/li>\n
- Other medical problems including:\n
\n- blood or blood vessel<\/span> disease<\/li>\n
- kidney disease<\/li>\n
- \ninflammatory<\/span> gastrointestinal disease<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n
<\/span>Side effects of gold compounds.<\/span><\/h2>\nIn addition to their useful effects, gold compounds can also cause many side effects, some of which can be serious. These include:<\/p>\n
\n- Skin rashes or itching: Generally mild, but in some cases may require stopping treatment<\/li>\n
- \nUlcers<\/span>, sores or white spots on the lips or in the mouth or throat<\/li>\n
- Skin pigmentation<\/span> for prolonged treatment (chrysiasis)<\/li>\n
- Loose stools or diarrhea: Generally mild and transient.<\/li>\n
- Stomach pain or cramps, bloating, gas, or indigestion.<\/li>\n
- Decreased or loss of appetite.<\/li>\n
- Nausea or vomiting<\/li>\n
- Decreased white blood cell count, possibly leading to blood disorders.<\/li>\n
- Transient abnormalities in liver and kidney function tests.<\/li>\n
- Confusion and seizures<\/li>\n<\/ul>\n
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<\/span>Pharmacological interactions with gold compounds.<\/span><\/h2>\nThere is very little specific information on the interactions of gold compounds with other drugs. However, the potential to increase gold toxicity is great, particularly when administered with other medications that have an effect on the kidney, liver and blood systems. Such medications include penicillamine, aminoglycosides<\/span>, amphotericin B, penicillins, phenylbutazone, phenytoin, sulfonamides, non-steroidal anti-inflammatory drugs (NSAID<\/span>), acyclovir and alcohol.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"Introducci\u00f3n Los compuestos de oro se usan principalmente en el tratamiento de reumatoides. artritis. Sin embargo, pueden ser \u00fatiles en el tratamiento de algunas enfermedades de la piel, como el…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-7400","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7400","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=7400"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7400\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=7400"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=7400"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=7400"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}