{"id":7416,"date":"2020-04-24T09:50:36","date_gmt":"2020-04-24T12:50:36","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/acido-azelaico\/"},"modified":"2020-04-27T16:24:05","modified_gmt":"2020-04-27T19:24:05","slug":"azelaic-acid","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/acido-azelaico\/","title":{"rendered":"Azelaic acid"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_89 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/acido-azelaico\/#%C2%BFQue-es-el-acido-azelaico\" >What is azelaic acid?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/acido-azelaico\/#%C2%BFPara-que-se-usa-el-acido-azelaico\" >What is azelaic acid used for?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/acido-azelaico\/#%C2%BFComo-se-usa-la-crema-de-acido-azelaico\" >How do you use azelaic acid cream?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/acido-azelaico\/#%C2%BFLa-crema-de-acido-azelaico-tiene-algun-efecto-secundario\" >Does azelaic acid cream have any side effects?<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-es-el-acido-azelaico\"><\/span>What is azelaic acid?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Azelaic acid is a natural material produced by a yeast that lives on normal skin, <em>Malassezia furfur<\/em> (also know as <em>Pityrosporum ovale<\/em>)<\/p>\n<p>In New Zealand, azelaic acid is available in a 20% concentration as Skinoren\u2122 <span class=\"term\" data-term-id=\"1121\">Cream<\/span>Medicated, Acne-Derm\u2122 <span class=\"term\" data-term-id=\"1120\">Lotion<\/span> and Azclear Action medicated lotion. A foam preparation of azelaic acid was approved by the FDA and marked in the US in July 2015.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFPara-que-se-usa-el-acido-azelaico\"><\/span>What is azelaic acid used for?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Azelaic acid is used as <span class=\"term\" data-term-id=\"1330\">current<\/span> treatment for mild to moderate acne, and can be combined with oral antibiotics or hormone therapy. It is useful for comedonal acne and <span class=\"term\" data-term-id=\"490\">inflammatory<\/span> acne.<\/p>\n<p>Azelaic acid is:<\/p>\n<ul>\n<li>Antibacterial: reduces the growth of <span class=\"term\" data-term-id=\"935\">bacteria<\/span> at <span class=\"term\" data-term-id=\"1300\">follicle<\/span> (<em>Proprionibacterium acnes<\/em> and <em>Staphylococcus epidermidis<\/em>)<\/li>\n<li>\n<span class=\"term\" data-term-id=\"1572\">Keratolytic<\/span> and comedolytic: returns the disordered growth of the skin cells that cover the follicle to normal<\/li>\n<li>A scavenger of <span class=\"term\" data-term-id=\"1687\">free radicals<\/span> \u2013 that is, reduce <span class=\"term\" data-term-id=\"148\">inflammation<\/span>.<\/li>\n<\/ul>\n<p>Azelaic acid also helps reduce <span class=\"term\" data-term-id=\"1521\">pigmentation<\/span>, making it particularly useful for dark-skinned patients whose acne spots leave persistent brown marks (<span class=\"term\" data-term-id=\"1621\">post-inflammatory<\/span> pigmentation) or who have melasma.<\/p>\n<p>Although not registered in New Zealand for other skin disorders, azelaic acid cream may also be useful in the treatment of:<\/p>\n<ul>\n<li>Rosacea<\/li>\n<li>\n<span class=\"term\" data-term-id=\"1392\">Lentigo<\/span> malignant, a type of precocious <span class=\"term\" data-term-id=\"1670\">melanoma<\/span>. Azelaic acid is not recommended for most cases of this precancerous <span class=\"term\" data-term-id=\"164\">injury<\/span>; Where possible, surgery should be performed.<\/li>\n<\/ul>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFComo-se-usa-la-crema-de-acido-azelaico\"><\/span>How do you use azelaic acid cream?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Azelaic acid cream should be applied to the acne-affected area initially daily, then if tolerated, build up to a generous application twice daily after thoroughly cleansing the skin.<\/p>\n<p>Acne responds slowly to treatment. Some improvement should be seen after one month of using azelaic acid cream. Further improvement with maximum results should occur after six months of continuous use. Treatment can be continued safely for months or years if acne remains active.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFLa-crema-de-acido-azelaico-tiene-algun-efecto-secundario\"><\/span>Does azelaic acid cream have any side effects?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Azelaic acid is non-toxic and well tolerated by most subjects. However, those with very sensitive skin or who suffer from <span class=\"term\" data-term-id=\"491\">eczema<\/span>, may be irritating to apply, resulting in a slight <span class=\"term\" data-term-id=\"1168\">irritating<\/span> <span class=\"term\" data-term-id=\"53\">dermatitis<\/span>.<\/p>\n<p>Stop applying the cream and seek medical attention if you develop serious illness:<\/p>\n<ul>\n<li>Redness<\/li>\n<li><span class=\"term\" data-term-id=\"384\">Climbing<\/span><\/li>\n<li>itching<\/li>\n<li>Burning<\/li>\n<\/ul>\n<p>Azelaic acid does not produce:<\/p>\n<ul>\n<li>\n<span class=\"term\" data-term-id=\"937\">Bacterial<\/span> antibiotic resistance\n<\/li>\n<li>Reduction in <span class=\"term\" data-term-id=\"898\">tallow<\/span> production<\/li>\n<li>\n<span class=\"term\" data-term-id=\"706\">Photosensitivity<\/span> (easy sunburn)<\/li>\n<li>Skin or clothing stains.<\/li>\n<li>Whitening skin or normal clothing.<\/li>\n<\/ul>\n<div class=\"grey-box\"><em><span style=\"font-size: 0.9em;\">New Zealand approved data sheets are the official source of information for these prescription drugs, including approved uses and risk information. See the New Zealand individual data sheet on the Medsafe website.<\/span><\/em><\/div>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>\u00bfQu\u00e9 es el \u00e1cido azelaico? El \u00e1cido azelaico es un material natural producido por una levadura que vive en la piel normal, Malassezia furfur (tambi\u00e9n conocido como Pityrosporum ovale) En&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-7416","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7416","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=7416"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7416\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=7416"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=7416"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=7416"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}