<\/span><\/h2>\nJuvenile xanthogranuloma (JXG) has also been called naevoxanthoendothelioma, multiple xanthoma, juvenile xanthoma, multiple eruptive xanthoma in childhood, congenital<\/span> xanthoma tuberosum, naeviform and juvenile giant cell xanthoma granuloma<\/span>.<\/p>\n<\/span>What is juvenile xanthogranuloma?<\/span><\/h2>\nJuvenile xanthogranuloma is a non-Langerhan cell type histiocytosis<\/span> (Class IIb). It presents as skin lesions predominantly in infants and young children, more frequently in males, and is present at birth in 20% of cases. However, 10% of the cases are adults. It is more common in Caucasians than in those of Eastern origin. The cause is unknown.<\/p>\nAt first, the lesions are soft, pinkish bumps, but later they develop a yellowish appearance and may become scaly<\/span>. Most are less than 0.5 cm in diameter (papules<\/span>), but giant nodules<\/span> it can be as large as 2 cm. They can arise anywhere on the body, but appear most often on the trunk and upper extremities. Occasionally they also appear in the eyes or internal organs.<\/p>\n\n<\/span>Juvenile xanthogranulomas<\/span><\/h5>\n<\/section>\n\n\n
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Juvenile xanthogranuloma<\/p>\n
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Juvenile xanthogranuloma<\/p>\n
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Juvenile xanthogranuloma<\/p>\n
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Juvenile xanthogranuloma<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>\nDifferential diagnosis<\/span> juvenile xanthogranuloma <\/span><\/h2>\nJuvenile xanthogranuloma is difficult to distinguish from several other conditions.<\/p>\n
\n- \nBenign<\/span> cephalic<\/span> histiocytosis<\/li>\n
- \nGeneralized<\/span> eruptive histiocytosis<\/li>\n
- \nPapular<\/span> xanthogranuloma<\/li>\n<\/ul>\n
They are increasingly viewed as the same condition.<\/p>\n
\n\n\n| Benign cephalic histiocytosis<\/th>\n<\/tr>\n |
\n\n\n- It usually occurs in infants under one year of age.<\/li>\n
- It presents with multiple small reddish-brown bumps on the skin, mainly on the head and neck.<\/li>\n
- The bumps resolve spontaneously over months or years, and often no visible marks remain.<\/li>\n
- Repeated attacks can occur<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
\n| Generalized eruptive histiocytoma<\/th>\n<\/tr>\n | \n\n\n- Usually affects adults<\/li>\n
- Presents with hundreds of reddish-brown, blue-red, or skin-colored papules (less than 1 cm) on the skin of the trunk, face, upper arms, and thighs<\/li>\n
- \nRecurrent<\/span> Lesion cultures may appear and disappear spontaneously after several months.<\/li>\n
- Can leave scars<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
\n| Papular xanthogranuloma<\/th>\n<\/tr>\n | \n\n\n- It occurs in children and adults.<\/li>\n
- Papules occur on the skin and in adults, on the lining of the mouth.<\/li>\n
- It resolves spontaneously in children but may persist in adults<\/li>\n
- There is no effective treatment at this time.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
<\/span>How are these disorders diagnosed?<\/span><\/h2>\nJuvenile xanthogranuloma has a characteristic appearance on dermoscopy, known as "sunset," in which there is a yellowish central area surrounded by a reddish periphery.<\/p>\n The diagnosis of juvenile xanthogranuloma and related conditions can be confirmed by a skin. biopsy<\/span>. Lesions are composed of collections of histiocytes<\/span>; see juvenile xanthogranuloma pathology<\/span>. In older lesions, the histiocytes may appear foamy, filled with lipids<\/span> (fat) or very enlarged (giant cells<\/span>)<\/p>\nDespite the fat-filled histiocytes in the skin, lipid levels in the blood are quite normal, and juvenile xanthogranuloma and related disorders are generally not associated with any serious abnormalities. However, the 20% also has latte macules<\/span>. Multiple latte birthmarks are associated with neurofibromatosis<\/span> Type 1.<\/p>\n<\/span>Treatment of juvenile xanthogranuloma<\/span><\/h2>\nUnless they occur in the eyes, juvenile xanthogranulomas are harmless growths and shrink and then eventually disappear for 2\u20133 years, usually without scarring.<\/p>\n Although individual lesions can be cut, this will leave a scar<\/span>. Removal is seldom necessary.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"Otros nombres para juvenil xantogranuloma El xantogranuloma juvenil (JXG) tambi\u00e9n se ha denominado naevoxanthoendothelioma, xantoma m\u00faltiple, xantoma juvenil, xantoma eruptivo m\u00faltiple en la infancia, cong\u00e9nito xantoma tuberosum, xantoma naeviforme y…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-7478","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7478","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=7478"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7478\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=7478"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=7478"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=7478"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}} | | |