<\/span><\/h2>\nAcute blistering diseases can be generalized<\/span> or located<\/span> to a body site and are due to infection<\/span> or inflammatory<\/span> disorders although more commonly eczematous<\/span>, widespread acute blisters can be life threatening and often require hospitalization.<\/p>\n Acute blistering conditions should be investigated by taking swabs to bacterial<\/span> and viral culture<\/span>. A skin biopsy<\/span> It can be useful to make a diagnosis.<\/p>\n<\/span>Acute generalized blistering diseases<\/span><\/h3>\nAcute febrile<\/span> neutrophilic<\/span> skin disease<\/span> <\/p>\n\n- Neck, limbs, upper trunk<\/li>\n
- Pseudovesicular plates<\/span>blisters pustules<\/span>, purple<\/span>or ulceration<\/span>\n<\/li>\n
- Disease associations: rheumatoid arthritis<\/span>Inflammatory bowel disease autoimmune<\/span> arthritis, myeloid<\/span> dysplasia<\/span><\/span>\n<\/li>\n
- Suggestive biopsy<\/li>\n<\/ul>\n
Atypical<\/span> enterovirus infection <\/p>\n\n- \nExtended<\/span> vesicular<\/span> eruption<\/span>\n<\/li>\n
- It clears in a few days.<\/li>\n
- When it affects areas of atopic<\/span> eczema<\/span>The enteroviral infection is called eczema coxsackium.<\/li>\n<\/ul>\n
Chicken pox \/ chicken pox <\/p>\n
\n- Childhood illness; more severe in adults<\/span><\/li>\n
- Scalp, face, oral mucous membrane<\/span>, trunk<\/span><\/li>\n
- Culture\/PCR<\/span> Herpes chickenpox zoster<\/span><\/li>\n<\/ul>\n\n
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Acute febrile neutrophilic dermatosis. <\/p>\n
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Atypical enterovirus infection<\/p>\n
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Chicken pox \/ chicken pox<\/p>\n<\/p><\/div>\n<\/section>\n
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Herpetic eczema <\/p>\n
\n- Atopic history dermatitis<\/span>\n<\/li>\n
- \nMonomorphic<\/span> group of umbilical<\/span> vesicles<\/li>\n
- Herpes simplex culture \/ PCR\n<\/li>\n<\/ul>\n
Dermatitis<\/p>\n
\n- \nAtopic dermatitis<\/span> <\/span>\n<\/li>\n
- \nDiscoid<\/span> eczema<\/span> <\/li>\n<\/ul>\n\n
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Discoid eczema<\/p>\n
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Herpetic eczema<\/p>\n
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Atopic dermatitis<\/p>\n<\/p><\/div>\n<\/section>\n
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Polymorphic<\/span> light eruption <\/p>\n\n- It affects the sites of the body exposed to the sun (hands, upper chest, feet<\/li>\n
- \nPapules<\/span>plates sometimes targettoid<\/span>\n<\/li>\n
- May have spare face<\/li>\n
- Arises within hours of exposure to bright sunlight<\/li>\n<\/ul>\n
Erythema<\/span> multiform <\/p>\n\n- A reaction, for example, to an infection.<\/li>\n
- An acute rash of papules, plaques, target lesions\n<\/li>\n
- \nAcral<\/span> distribution<\/span>: cheeks, elbows, knees, hands, feet<\/li>\n
- Can have mucositis<\/span> (lips, conjunctiva<\/span>genitals)<\/li>\n<\/ul>\n
Stevens-Johnson syndrome<\/span> \/ \/ toxic<\/span> epidermal<\/span> necrolysis<\/p>\n\n- Very bad patient<\/span><\/li>\n
- Mucous membrane<\/span> intervention<\/span><\/li>\n
- Almost always drug induced<\/span><\/li>\n
- Rarely due to mycoplasma infection<\/span><\/li>\n
- Painful red skin may peel off sheets or have multiple uniting<\/span> blisters<\/span><\/li>\n<\/ul>\n\n
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Polymorphic light eruption<\/p>\n
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Erythema multiforme<\/p>\n
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Stevens Johnson Syndrome \/ Toxic Epidermal Necrolysis<\/p>\n<\/p><\/div>\n<\/section>\n
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Drug hypersensitivity<\/span> syndrome <\/p>\n\n- Medication started up to 8 weeks before start<\/li>\n
- \nMorbid<\/span> blistering rash (without necrolysis)<\/li>\n
- Often mucosal involvement<\/li>\n
- Multi-organ damage (renal<\/span>, hepatic<\/span>respiratory hematological<\/span>)<\/li>\n
- Often marked eosinophilia<\/span>\n<\/li>\n<\/ul>\n
Staphylococcal scalded skin syndrome <\/p>\n
\n- Little boy<\/span><\/li>\n
- Miserable<\/span><\/li>\n
- Red skin comes out on sheets<\/span><\/li>\n
- Evidence of staphylococcal infection<\/span><\/li>\n<\/ul>\n\n
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Drug hypersensitivity syndrome<\/p>\n
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Staphylococcal scalded skin syndrome<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>Acute localized blistering diseases<\/span><\/h3>\nAcute dermatitis<\/p>\n
\n- Contact dermatitis<\/li>\n
- Plant dermatitis <\/li>\n
- Pompholyx<\/li>\n<\/ul>\n
Bullous<\/span> impetigo <\/p>\n\n- Quickly expanding license plate<\/span>\n<\/li>\n
- Staphylococcus aureus swab\n<\/li>\n
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Wound infections, scabies, etc.<\/li>\n<\/ul>\n
Chilblains <\/p>\n
\n- Toes<\/span><\/li>\n
- Exposed to cold<\/span><\/li>\n
- Purple tender plates<\/span><\/li>\n<\/ul>\n\n
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Plant dermatitis<\/p>\n
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Blistering impetigo<\/p>\n
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Chilblains<\/p>\n<\/p><\/div>\n<\/section>\n
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Enteroviral vesicular stomatitis<\/span> <\/p>\n