\n| Autosomal recessive<\/td>\n | Two copies of the faulty gene must be inherited for the disease to be present. A child must inherit a faulty gene from both parents. The risk of transmitting an autosomal recessive disease is 25% for each pregnancy.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Acquired complexion lax can develop at any age, but it often begins in adulthood. It can occur spontaneously or in 50% cases develop after episodes of urticaria<\/span> or angioedema<\/span>extensive inflammatory<\/span> skin disease (eg. eczema<\/span>, erythema<\/span> multiform, blisters eruption<\/span>) or hypersensitivity<\/span> reactions to penicillin or other drugs.<\/p>\nThe actual underlying cause of cutis laxa is unknown. Several mechanisms appear to be involved in the reduction of elastic fibers.<\/p>\n \n \n \n \n<\/div><\/div><\/div><\/div>\n <\/span>What are the clinical characteristics of cutis laxa?<\/span><\/h2>\nThe clinical features of cutis laxa are different depending on how the condition is inherited.<\/p>\n \n\n\n| Heritage<\/th>\n | Clinical features<\/th>\n<\/tr>\n | \n| X-linked<\/td>\n | \n\n- Loose skin<\/li>\n
- Loose joints (joint hyperextensibility)<\/li>\n
- Bone abnormalities such as aquiline nose, pigeon breast and funnel<\/li>\n
- Frequent loose stools and urinary tract obstructions<\/li>\n
- Mild mental retardation<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
\n| Autosomal dominant<\/td>\n | \n\n- Skin changes can start at any age.<\/li>\n
- Hanging loose skin may be the only feature<\/li>\n
- Facial participation is universal.<\/li>\n
- \nSystemic<\/span> participation is rare<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
\n| Autosomal recessive (types I and II)<\/td>\n | \n\n- Symptoms and signs generally begin in childhood<\/li>\n
- Loose skin<\/li>\n
- Bone abnormalities (eg, delayed union of skull bones, hip dislocation, spinal curvature)<\/li>\n
- Emphysema (lung disease causing dyspnea)<\/li>\n
- Hernias<\/li>\n
- Diverticula (bags) in the esophagus, duodenum, and bladder.<\/li>\n
- \nAortic<\/span> aneurysm (bulging aorta, the main artery leaving the heart)<\/li>\n<\/ul>\n
Type i:<\/p>\n \n- Severe form<\/li>\n
- Present at birth<\/li>\n
- Emphysema early in life<\/li>\n<\/ul>\n
Type II<\/p>\n \n- Growth retardation<\/li>\n
- Generally present at birth<\/li>\n
- Severe on hands, feet and abdomen<\/li>\n
- \nBilateral<\/span> congenital<\/span> hip dislocation<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
The characteristics of acquired loose skin are mainly loose skin, especially in areas of the anterior inflammation<\/span>. It has also happened in association with complement<\/span> deficiency (C3 and C4), systemic lupus erythematosus, sarcoidosis, multiple myeloma, and systemic amyloidosis.<\/p>\n<\/span>Characteristics of lax complexion skin<\/span><\/h3>\nAny part of the body can be affected. In inherited forms of loose skin, the appearance of loose skin is most prominent around the eyes, face, neck, shoulders, and thighs. The characteristics of the skin include:<\/p>\n \n- Loose, inelastic and hanging skin folds<\/li>\n
- Loose skin that hangs around the face and neck, giving you the look of a hound and a patient who looks much older than he really is<\/li>\n
- Reduced elastic recoil when the skin is stretched.<\/li>\n<\/ul>\n
<\/span>How is cutis laxa diagnosed?<\/span><\/h2>\nCutis laxa is generally diagnosed clinically, due to its unique clinical characteristics. the pathology<\/span> of loose complexion on the skin biopsy<\/span> It can be useful<\/p>\n<\/span>What is the treatment for cutis laxa?<\/span><\/h2>\nThere is no specific treatment for cutis laxa or to prevent disease progression. Treatment is aimed at managing any complications that may arise from the involvement of the associated internal organs.<\/p>\n Cosmetic surgery can be performed to reduce redundant skin folds, but often only a temporary benefit. Patients with lax skin, particularly those with the autosomal dominant form, generally have a normal life expectancy.<\/p>\n<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":" Que es cutis laxa? Cutis laxa (lat\u00edn para piel floja o laxa) es un raro, heredado o adquirido tejido conectivo trastorno caracterizado por piel suelta que carece de elasticidad. La…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-7661","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7661","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=7661"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7661\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=7661"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=7661"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=7661"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}} | | | |