<\/span><\/h2>\nDermatofibrosarcoma protuberans (DFSP) es un local agresivo tumor<\/span> de origen fibrobl\u00e1stico. La inicial injury<\/span> es un color de piel license plate<\/span> que desarrolla un color rojo \/ marr\u00f3n y nodular<\/span> surface.<\/p>\n<\/span>\nHistology<\/span> de dermatofibrosarcoma protuberans<\/span><\/h2>\nEl dermatofibrosarcoma protuberans consiste en un proliferation<\/span> de c\u00e9lulas en forma de huso en las profundidades dermis<\/span> con lesiones posteriores infiltrando el subcutaneous<\/span> grasa (Figuras 1, 2). La invasi\u00f3n del m\u00fasculo puede ocurrir. A menudo hay un ahorro superficial, sin embargo, la participaci\u00f3n de la epidermis<\/span> and ulceration<\/span> a veces se ve Las c\u00e9lulas tumorales spindled son bastante uniformes en apariencia con alargado nuclei<\/span> y poco o nada pleomorphism<\/span> (Figuras 3-5) y se pueden disponer de manera tormentosa (remolinos y entretejidos, figura 6).<\/p>\n\n<\/span>Dermatofibrosarcoma pathology protuberans<\/span><\/h5>\n<\/section>\n\n\n
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Figure 1<\/p>\n
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Figure 2<\/p>\n
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figure 3<\/p>\n
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Figure 4<\/p>\n
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Figure 5<\/p>\n
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Figure 6<\/p>\n
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Figure 7<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>Estudios especiales de dermatofibrosarcoma protuberans<\/span><\/h2>\nPositividad caracter\u00edstica para CD34 (Figura 7). CD31 negativo y actina del m\u00fasculo liso.<\/p>\n
<\/span>\nDifferential diagnosis<\/span> de dermatofibrosarcoma protuberans<\/span><\/h2>\nCellular<\/span> dermatofibroma: una proliferaci\u00f3n radial de c\u00e9lulas con n\u00facleos grandes. Puede tener hemosmosin<\/span> dep\u00f3sitos Parte central negativa para CD34, positiva para Factor XIIIa.<\/p>\nDermal<\/span> sarcoma<\/span> – marcado nuclear<\/span> polymorphism<\/span> y frecuente mitosis<\/span> son caracter\u00edsticas diferenciadoras del dermatofibrosarcoma protuberans.<\/p>\nLeiomyosarcoma<\/span> – pleomorphic<\/span> spindle cell<\/span> tumor con n\u00facleos en forma de cigarro y mitosis. Actina positiva del m\u00fasculo liso.<\/p>\nDesmoplastic<\/span> melanoma<\/span> – fibrosis<\/span> and focal<\/span> lymphocytic<\/span> infiltrators<\/span> Son caracter\u00edsticas adicionales. Las c\u00e9lulas tumorales son positivas para S100.<\/p>\nNeurofibroma<\/span> – Tumor positivo de c\u00e9lulas fusiformes S100. Mast cells<\/span> may be present.<\/p>\nDermatofibrosarcoma protuberans fibrosarcomatoso: una variante del dermatofibrosarcoma protuberans que representa la progresi\u00f3n del tumor. Se presenta un patr\u00f3n focal fascicular o de espina de pescado. M\u00e1s dermatofibrosarcoma protuberans celular que lo habitual con aumento del pleomorfismo nuclear y mitotic<\/span> recuento de figuras. La tinci\u00f3n para CD34 se reduce.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"Introducci\u00f3n Dermatofibrosarcoma protuberans (DFSP) es un local agresivo tumor de origen fibrobl\u00e1stico. La inicial lesi\u00f3n es un color de piel placa que desarrolla un color rojo \/ marr\u00f3n y nodular…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-7859","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7859","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=7859"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/7859\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=7859"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=7859"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=7859"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}