<\/span><\/h2>\nThe scanning power view of eosinophilic fasciitis shows a sclerosing process that affects depth subcutaneous<\/span> tissue and fascia<\/span> (Figure 1). In early disease there is edema<\/span> of the fascia and subcutaneous tissue with a lymphocytic<\/span> infiltrate<\/span> containing plasma<\/span> cells and eosinophils<\/span>. Over time collagen<\/span> it thickens and sclerotic<\/span> (Figure 2) with extension towards the subcutaneous fibrous septa. Lobular involvement is rare. Tissue eosinophils can be focal<\/span> around attached<\/span> structures or diffuse<\/span> within the tissue infiltrate (Figure 3). In more involved cases, changes can extend to dermis<\/span>. the epidermis<\/span> normally not involved, albeit mild atrophy<\/span> It can be seen in a minority of cases.<\/p>\n\n<\/span>Eosinophilic fasciitis pathology<\/span><\/h5>\n<\/section>\n\n\n
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Figure 1<\/p>\n
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Figure 2<\/p>\n
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figure 3<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>\nDifferential diagnosis<\/span> eosinophilic fasciitis<\/span><\/h2>\nScleroderma<\/span>: Involvement of the epidermis and upper dermis is rare in eosinophilic fasciitis, particularly in early lesions. A significant number of eosinophils in the infiltrate would not favor scleroderma.<\/p>\nArthropod<\/span> bite reaction: although a deep eosinophilic infiltrate may be seen, the extension to and beyond the subcutaneous tissue is atypical<\/span>. The presence of superficial epidermal<\/span> and dermal<\/span> the changes would argue against eosinophilic fasciitis.<\/p>\nProliferative<\/span> fasciitis: in addition to fascial fibrosis<\/span> there are great ganglion<\/span> like cells and a pauci-inflammatory<\/span> myxoid<\/span> stroma<\/span>.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"Histolog\u00eda de eosinof\u00edlica fascitis La vista del poder de escaneo de la fascitis eosinof\u00edlica muestra un proceso esclerosante que afecta la profundidad subcut\u00e1neo tejido y fascia (Figura 1). En la…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-8056","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8056","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=8056"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8056\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=8056"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=8056"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=8056"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}