{"id":8173,"date":"2020-04-27T11:33:55","date_gmt":"2020-04-27T14:33:55","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/enfermedad-de-flegel\/"},"modified":"2020-04-27T14:12:08","modified_gmt":"2020-04-27T17:12:08","slug":"phlegels-disease","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-flegel\/","title":{"rendered":"Flegel&#039;s disease"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-flegel\/#%C2%BFQue-es-la-enfermedad-de-Flegel\" >What is Flegel&#039;s disease?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-flegel\/#%C2%BFQue-causa-la-enfermedad-de-Flegel\" >What causes Flegel&#039;s disease?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-flegel\/#%C2%BFCuales-son-las-caracteristicas-clinicas-de-la-enfermedad-de-Flegel\" >What are the clinical features of Flegel&#039;s disease?<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-flegel\/#Enfermedad-de-Flegel\" >Flegel&#039;s disease<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-flegel\/#%C2%BFComo-se-diagnostica-la-enfermedad-de-Flegel\" >How is Flegel&#039;s disease diagnosed?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/enfermedad-de-flegel\/#%C2%BFQue-tratamiento-hay-disponible\" >What treatment is available?<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-es-la-enfermedad-de-Flegel\"><\/span>What is Flegel&#039;s disease?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Flegel&#039;s disease is also known as <span class=\"term\" data-term-id=\"610\">hyperkeratosis<\/span> lenticularis perstans. It was first described by Flegel in 1958. It is characterized by a red-brown color. <span class=\"term\" data-term-id=\"366\">papules<\/span> with irregular horny scales located mainly on the upper surface of the feet and legs. It is very similar to Kyrle&#039;s disease and has been considered as a variant of Kyrle&#039;s disease, however, its clinical and pathological picture is different enough to make it its own disease entity.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-causa-la-enfermedad-de-Flegel\"><\/span>What causes Flegel&#039;s disease?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The cause of the disease is unknown. It is believed to be an inherited condition, although cases have been reported where there is no family history of the disease. Sun exposure has also been implicated but not proven.<\/p>\n<p>Flegel&#039;s disease has been reported to rarely affect some families who are also prone to skin and gastrointestinal cancers.<\/p>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCuales-son-las-caracteristicas-clinicas-de-la-enfermedad-de-Flegel\"><\/span>What are the clinical features of Flegel&#039;s disease?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The lesions are small, reddish brown, 1\u20135 mm. <span class=\"term\" data-term-id=\"385\">scaly<\/span> papules that appear most commonly on the upper surface of the feet and legs. removal of the <span class=\"term\" data-term-id=\"320\">scale<\/span> reveals a bright red base, often with pinpoint hemorrhage. Rarely, the external ear lobes, arms, palms, soles, and mouths. <span class=\"term\" data-term-id=\"189\">mucous membrane<\/span> they can be affected. The papules are usually not painful.<\/p>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Enfermedad-de-Flegel\"><\/span>Flegel&#039;s disease<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='flegel1__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildg1xq-6560391-1619927' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/flegel1__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDg1XQ-6560391.jpg'>\n<\/div>\n<p class=\"p-small\">Flegel&#039;s disease<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='flegel2__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildg1xq-1002045-8106925' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/flegel2__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDg1XQ-1002045.jpg'>\n<\/div>\n<p class=\"p-small\">Flegel&#039;s disease<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='flegel3__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-2696083-7160891' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/flegel3__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-2696083.jpg'>\n<\/div>\n<p class=\"p-small\">Flegel&#039;s disease<\/p>\n<\/p><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFComo-se-diagnostica-la-enfermedad-de-Flegel\"><\/span>How is Flegel&#039;s disease diagnosed?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Flegel&#039;s disease is sometimes diagnosed clinically, especially if there is a family history of Flegel&#039;s disease. Otherwise, a <span class=\"term\" data-term-id=\"24\">biopsy<\/span> can lead to a pathological diagnosis of Flegel&#039;s disease.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-tratamiento-hay-disponible\"><\/span>What treatment is available?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>injuries are <span class=\"term\" data-term-id=\"22\">benign<\/span> and are treated primarily for cosmetic reasons. Treatment of Flegel&#039;s disease includes:<\/p>\n<ul>\n<li>\n<span class=\"term\" data-term-id=\"1330\">Current<\/span> 5% fluorouracil <span class=\"term\" data-term-id=\"1121\">cream<\/span> used for several months<\/li>\n<li>Dermabrasion<\/li>\n<li><span class=\"term\" data-term-id=\"1145\">Cryotherapy<\/span><\/li>\n<li>Current <span class=\"term\" data-term-id=\"761\">retinoid<\/span> <\/li>\n<li>An oral retinoid such as acitretin or isotretinoin.<\/li>\n<\/ul>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>\u00bfQu\u00e9 es la enfermedad de Flegel? La enfermedad de Flegel tambi\u00e9n se conoce como hiperqueratosis lenticularis perstans. Fue descrito por primera vez por Flegel en 1958. Se caracteriza por un&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-8173","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8173","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=8173"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8173\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=8173"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=8173"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=8173"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}