{"id":8193,"date":"2020-04-27T13:38:14","date_gmt":"2020-04-27T16:38:14","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/patologia-del-hamartoma-quistico-foliculosebaceo\/"},"modified":"2020-04-30T21:27:45","modified_gmt":"2020-05-01T00:27:45","slug":"pathology-of-cystic-folliculosebaceous-hamartoma","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-del-hamartoma-quistico-foliculosebaceo\/","title":{"rendered":"Pathology of folliculosebaceous cystic hamartoma"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-del-hamartoma-quistico-foliculosebaceo\/#Introduccion\" >Introduction<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-del-hamartoma-quistico-foliculosebaceo\/#Histologia-del-hamartoma-quistico-foliculosebaceo\" >Histology of folliculosebaceous cystic hamartoma<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-del-hamartoma-quistico-foliculosebaceo\/#Patologia-del-hamartoma-quistico-foliculosebaceo\" >Pathology of folliculosebaceous cystic hamartoma<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/patologia-del-hamartoma-quistico-foliculosebaceo\/#Diagnostico-diferencial-del-hamartoma-quistico-foliculosebaceo\" >Differential diagnosis of folliculosebaceous cystic hamartoma<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<h2 class=\"normal\"><span class=\"ez-toc-section\" id=\"Introduccion\"><\/span>Introduction<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"normal\">Sebaceous follicle <span class=\"term\" data-term-id=\"1306\">cystic<\/span> <span class=\"term\" data-term-id=\"345\">hamartoma<\/span> represents a <span class=\"term\" data-term-id=\"47\">cutaneous<\/span> biphasic hamartoma It consists of <span class=\"term\" data-term-id=\"847\">epithelial<\/span> and mesenchymal components in varying proportions, typically occurring in adults in the head and neck area. Various pathogenic mechanisms underlying this <span class=\"term\" data-term-id=\"1827\">attached<\/span> <span class=\"term\" data-term-id=\"195\">neoplasm<\/span> has been proposed. However, there is still much controversy over whether it represents a distinct entity or part of an evolutionary spectrum of tricholliculomas (TF). Since the introduction of this entity in 1991, there have been a few case reports documenting a variety of mesenchymal changes observed in FCH, as well as rare and unusual associations.<\/p>\n<h2 class=\"normal\"><span class=\"ez-toc-section\" id=\"Histologia-del-hamartoma-quistico-foliculosebaceo\"><\/span>\n<span class=\"term\" data-term-id=\"128\">Histology<\/span> of folliculosebaceous cystic hamartoma<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"normal\"><span>Follicular cystic hamartoma<\/span> It is a cutaneous hamartoma of epithelial and mesenchymal elements and focuses mainly on <span class=\"term\" data-term-id=\"61\">dermis<\/span>. The epithelial components of <span>folliculosebaceous cystic hamartoma<\/span> comprise distorted follicular cystic distorted <span class=\"term\" data-term-id=\"1824\">proliferations<\/span> while mesenchymal components commonly include <span class=\"term\" data-term-id=\"1830\">fibroplasia<\/span>, <span class=\"term\" data-term-id=\"753\">vascular<\/span> and proliferations of adipose tissue.<\/p>\n<p class=\"normal\">Scan view shows dilated <span class=\"term\" data-term-id=\"107\">follicular<\/span> structure or structures, with radiant matures <span class=\"term\" data-term-id=\"262\">sebaceous<\/span> lobes (Figures 1, 2). Surrounding the distorted <span class=\"term\" data-term-id=\"122\">hair<\/span> <span class=\"term\" data-term-id=\"1301\">follicles<\/span> There may be thin anastomosing epithelial strands (Figure 3). the <span class=\"term\" data-term-id=\"1655\">stroma<\/span> surrounding epithelial units is frequently made up of dense <span class=\"term\" data-term-id=\"1185\">collagen<\/span> tissue (Figure 1-3) and can show prominent <span class=\"term\" data-term-id=\"1834\">cleft<\/span> to the surroundings <span class=\"term\" data-term-id=\"1351\">adjacent<\/span> unaffected dermis (figure 1). Additional stromal changes may include increased vascularity or pockets of <span class=\"term\" data-term-id=\"549\"><span class=\"term\" data-term-id=\"1904\">adipocytes<\/span><\/span>  consistent with the increase in stromal fat (figure 4). <\/p>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Patologia-del-hamartoma-quistico-foliculosebaceo\"><\/span>Pathology of folliculosebaceous cystic hamartoma<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='fch-figure1__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildhd-5214774-9178663' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/fch-figure1__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDhd-5214774.jpg'>\n<\/div>\n<p class=\"p-small\">Figure 1<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='fch-figure2__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildbd-6323676-6933055' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/fch-figure2__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDBd-6323676.jpg'>\n<\/div>\n<p class=\"p-small\">Figure 2<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='fch-figure3__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildvd-7105208-6887790' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/fch-figure3__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDVd-7105208.jpg'>\n<\/div>\n<p class=\"p-small\">figure 3<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='fch-figure4__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-3482609-5325406' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/fch-figure4__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-3482609.jpg'>\n<\/div>\n<p class=\"p-small\">Figure 4<\/p>\n<\/p><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2 class=\"normal\"><span class=\"ez-toc-section\" id=\"Diagnostico-diferencial-del-hamartoma-quistico-foliculosebaceo\"><\/span>\n<span class=\"term\" data-term-id=\"813\">Differential diagnosis<\/span> of folliculosebaceous cystic hamartoma<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"normal\">Trichofolliculoma: Attempts to distinguish sebaceous trichofolliculoma from <span>folliculosebaceous cystic hamartoma<\/span> Clinical and histological studies have been performed. The latter has been suggested <span class=\"term\" data-term-id=\"164\">injury<\/span> it presents clinically as a hairless papulonodular lesion. <span class=\"term\" data-term-id=\"1669\">Histologically<\/span>FSH demonstrates more prominent stromal mesenchymal abnormalities.<\/p>\n<p class=\"normal\">In contrast, sebaceous trichofolliculoma presents clinically as a depressed lesion with a <span class=\"term\" data-term-id=\"704\">eruption<\/span> of terminal or hairy hairs. Histologically, there is an almost constant dilatation connection <span class=\"term\" data-term-id=\"1304\">infundibular<\/span> structure with the <span class=\"term\" data-term-id=\"85\">epidermis<\/span>. However, the characteristics described above are not absolute. There have been clinical descriptions of <span>folliculosebaceous cystic hamartoma<\/span> associated with hair, and hair stems have also been identified within cystic structures in <span>folliculosebaceous cystic hamartoma<\/span>. Similarly, the finding of a direct connection to the epidermis by the cystic structure is not exclusively found in sebaceous tricholliculoma and has been described in cases of <span>folliculosebaceous cystic hamartoma<\/span>.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>Introducci\u00f3n Foliculoseb\u00e1ceo c\u00edstico hamartoma representa un cut\u00e1neo hamartoma bif\u00e1sico Se compone de epitelial y componentes mesenquimales en proporciones variables, que ocurren t\u00edpicamente en adultos en el \u00e1rea de la cabeza&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-8193","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8193","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=8193"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8193\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=8193"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=8193"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=8193"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}