{"id":8282,"date":"2020-04-28T00:23:37","date_gmt":"2020-04-28T03:23:37","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/wiki\/sindrome-hipereosinofilico\/"},"modified":"2020-10-30T07:30:44","modified_gmt":"2020-10-30T10:30:44","slug":"sindrome-hipereosinofilico","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/sindrome-hipereosinofilico\/","title":{"rendered":"Hypereosinophilic syndrome"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/sindrome-hipereosinofilico\/#%C2%BFQue-es-hipereosinofilico-sindrome\" >\u00bfQu\u00e9 es hipereosinof\u00edlico? s\u00edndrome?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/sindrome-hipereosinofilico\/#Como-se-ve\" >C\u00f3mo se ve?<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/sindrome-hipereosinofilico\/#Sindrome-hipereosinofilico\" >Hypereosinophilic syndrome<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/sindrome-hipereosinofilico\/#Investigaciones\" >Research<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/sindrome-hipereosinofilico\/#Tratamiento\" >Treatment<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-es-hipereosinofilico-sindrome\"><\/span>\u00bfQu\u00e9 es hipereosinof\u00edlico? <span class=\"term\" data-term-id=\"350\">syndrome<\/span>?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>El s\u00edndrome hipereosinof\u00edlico es una condici\u00f3n rara definida por tres criterios:<\/p>\n<ol>\n<li>Un conteo sangu\u00edneo muestra un mayor n\u00famero de <span class=\"term\" data-term-id=\"448\">eosinophils<\/span> (mayor de 1500 eosin\u00f3filos \/ uL) persistente durante al menos 6 meses<\/li>\n<li>Signos y s\u00edntomas debido a la afectaci\u00f3n de varios \u00f3rganos internos.<\/li>\n<li>No hay evidencia de par\u00e1sitos, <span class=\"term\" data-term-id=\"1136\">allergy<\/span>u otras causas conocidas de una elevaci\u00f3n <span class=\"term\" data-term-id=\"447\">eosinophils<\/span> count.<\/li>\n<\/ol>\n<p>La afecci\u00f3n se produce principalmente en hombres (90%), generalmente en la mediana edad.<\/p>\n<p>Algunos pacientes tienen un trastorno sangu\u00edneo subyacente presente, m\u00e1s com\u00fanmente una forma de <span class=\"term\" data-term-id=\"613\">leukemia<\/span>. La leucemia tambi\u00e9n puede diagnosticarse hasta 9-12 a\u00f1os despu\u00e9s del diagn\u00f3stico inicial del s\u00edndrome hipereosinof\u00edlico.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Como-se-ve\"><\/span>C\u00f3mo se ve?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>El s\u00edndrome hipereosinof\u00edlico generalmente se presenta con <span class=\"term\" data-term-id=\"1176\">fever<\/span>, p\u00e9rdida de peso, fatiga y <span class=\"term\" data-term-id=\"255\">eruption<\/span>.<\/p>\n<p>Una erupci\u00f3n est\u00e1 presente en m\u00e1s del 50% de los pacientes, pero no es espec\u00edfica en apariencia. M\u00e1s com\u00fanmente, picaz\u00f3n hinchada roja <span class=\"term\" data-term-id=\"367\">nodules<\/span> (bultos) han sido descritos. Tambi\u00e9n puede parecerse <span class=\"term\" data-term-id=\"1646\">urticaria<\/span> (urticaria).<\/p>\n<p>A menudo hay un agrandamiento del h\u00edgado y el bazo, lo que indica afectaci\u00f3n del h\u00edgado y el bazo. Los pulmones, los ri\u00f1ones, el coraz\u00f3n y el sistema nervioso pueden verse afectados.<\/p>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Sindrome-hipereosinofilico\"><\/span>Hypereosinophilic syndrome<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='hypereos1__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildewof0-4204068-9968657' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/hypereos1__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDEwOF0-4204068.jpg'>\n<\/div>\n<p class=\"p-small\">Hypereosinophilic syndrome<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='hypereos2__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildexmf0-7997958-7550236' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/hypereos2__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDExMF0-7997958.jpg'>\n<\/div>\n<p class=\"p-small\">Hypereosinophilic syndrome<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='hypereos3__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingilde5xq-7352889-3823249' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/hypereos3__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDE5XQ-7352889.jpg'>\n<\/div>\n<p class=\"p-small\">Hypereosinophilic syndrome<\/p>\n<\/p><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Investigaciones\"><\/span>Research<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Un elevado <span class=\"term\" data-term-id=\"1374\">peripheral<\/span> El recuento de eosin\u00f3filos en sangre se encuentra en una prueba de recuento sangu\u00edneo completo.<\/p>\n<p>A skin <span class=\"term\" data-term-id=\"24\">biopsy<\/span> a menudo revela un <span class=\"term\" data-term-id=\"541\">infiltrate<\/span> de eosin\u00f3filos.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Tratamiento\"><\/span>Treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Aproximadamente el 70% de los pacientes responden a dosis altas de corticosteroides orales con prednisona oral, con <span class=\"term\" data-term-id=\"83\">eosinophilia<\/span> volviendo a los niveles normales. Otros tratamientos incluyen interfer\u00f3n alfa, <a class=\"wpil_keyword_link\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/hydroxyurea\/\" title=\"hydroxyurea\"><a class=\"wpil_keyword_link\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/hydroxyurea\/\" title=\"hydroxyurea\">hydroxyurea<\/a><\/a>, terapia PUVA y recientemente mesilato de imatinib (Gleevec\u00ae) en pacientes seleccionados. La supervivencia general de 5 a\u00f1os para pacientes con s\u00edndrome hipereosinof\u00edlico es del 80% y la causa de la muerte suele ser la insuficiencia card\u00edaca.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>\u00bfQu\u00e9 es hipereosinof\u00edlico? s\u00edndrome? El s\u00edndrome hipereosinof\u00edlico es una condici\u00f3n rara definida por tres criterios: Un conteo sangu\u00edneo muestra un mayor n\u00famero de eosin\u00f3filos (mayor de 1500 eosin\u00f3filos \/ uL)&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-8282","wiki","type-wiki","status-publish","format-standard"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8282","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=8282"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8282\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=8282"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=8282"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=8282"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}