\nWhat is Ito hypomelanosis?<\/span><\/p>\nIto's hypomelanosis is part of a rare genetic<\/span> neurocutaneous<\/span> syndrome<\/span>. It is characterized by:<\/p>\n\n- Striped, irregular, spiral or linear<\/span> hypopigmented<\/span> macules<\/span> that occurs in any part of the body<\/li>\n
- Palms, scalp and soles of the feet are generally not affected<\/li>\n
- The patterns that revolve around the trunk and the linear patterns for the legs and arms are called Blaschko lines.\n<\/li>\n
- Lesions first appear as small 0.5-1 cm white or hypopigmented macules that fuse to form larger patches.<\/li>\n
- Macules cover more than two dermatomes and are often on both sides of the body.<\/li>\n
- The patches are not symmetrical<\/span>\n<\/li>\n<\/ul>\n
Ito's hypomelanosis is also known as "incontinentia pigmenti achromians". <\/p>\n\n<\/span>Ito hypomelanosis<\/span><\/h5>\n<\/section>\n\n\n
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Ito hypomelanosis<\/p>\n<\/p><\/div>\n<\/section>\n
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<\/span>Abnormalities associated with Ito hypomelanosis<\/span><\/span><\/h2>\nAssociated abnormalities are believed to occur in 30-50% of patients with cutaneous<\/span> Injuries These include:<\/p>\n\n- Seizures<\/li>\n
- Mental retardation<\/li>\n
- Hearing abnormalities<\/li>\n
- Tooth or mouth problems<\/li>\n
- Visual problems<\/li>\n
- \nOrthopedic<\/span> problems<\/li>\n<\/ul>\n
<\/span>What is the cause of Ito hypomelanosis?<\/span><\/h2>\nIto hypomelanosis is believed to be due to chromosomal<\/span> mosaicism and sporadic mutations<\/span>. It is not an inherited disorder since the chromosomal defect occurs after conception. I specify gene<\/span>(s) is most likely a balanced translocation<\/span> from Xp21.2.<\/span><\/p>\n\n
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<\/span>\nHow is the diagnosis <\/span>of hypomelanosis of Ito done?<\/span>
\n<\/span><\/h2>\nIto hypomelanosis is present at birth and is usually detected by a dermatologist<\/span>, pediatrician or neurologist during the first or second year of life. Complete history taking and physical examination with attention to neurological <\/span>and ophthalmological<\/span> The findings are necessary to detect associated abnormalities.<\/p>\nAlthough recent research has estimated that 30-50% of Ito hypomelanosis patients have associated abnormalities, some studies report associated neurological abnormality rates as high as 75-94%.<\/p>\n
<\/span>What is the treatment for Ito hypomelanosis?<\/span><\/h2>\nThe cutaneous effects of Ito hypomelanosis do not require treatment. In many cases, the skin can develop. pigment<\/span> over time and mix well with normal skin. Patients who are aware of their appearance can use cosmetic camouflage.<\/p>\nAssociated abnormalities require appropriate medical treatment.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"
\u00bfQu\u00e9 es la hipomelanosis de Ito? La hipomelanosis de Ito es parte de un raro gen\u00e9tico neurocut\u00e1neo s\u00edndrome. Se caracteriza por: Rayado, irregular, en forma de espiral o lineal hipopigmentado…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-8288","wiki","type-wiki","status-publish","format-standard"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8288","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=8288"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8288\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=8288"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=8288"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=8288"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}