<\/span><\/h2>\nHand, foot, and mouth disease is rarely biopsied.<\/p>\n
Sections generally show acral<\/span> skin with a lymphocytic<\/span> infiltrate<\/span> which infiltrators<\/span> the epidermis<\/span> (Figure 1). The infiltrator is associated with keratinocytes<\/span> apoptosis<\/span> in early injuries (figure 2). Figure 3 shows a high-power view of more established lesions: there is papillary dermal<\/span> edema<\/span> (lower half of the field), epidermal<\/span> necrosis<\/span>, dyskeratosis<\/span>and intraepidermal<\/span> vesiculation as a consequence of epidermal edema.<\/p>\n\n<\/span>Pathology of the hand, foot and mouth disease<\/span><\/h5>\n<\/section>\n\n\n
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Figure 1<\/p>\n
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Figure 2<\/p>\n
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figure 3<\/p>\n<\/p><\/div>\n<\/section>\n
<\/div>\n
<\/span>Special studies for hand, foot and mouth disease.<\/span><\/h2>\nPCR<\/span> Tissue block studies can be performed to identify coxsackievirus A16 and enterovirus 71.<\/p>\n\n
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<\/span>\nDifferential diagnosis<\/span> hand, foot and mouth disease pathology<\/span>
\n<\/span><\/h2>\nErythema<\/span> Multiforme: Early lesions of hand, foot, and mouth disease can be very similar to erythema multiforme. The clinical correlation can be very useful.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"La enfermedad de manos, pies y boca es una enfermedad viral causada por el virus coxsackie A16 y el enterovirus 71. Histolog\u00eda de mano, fiebre aftosa La enfermedad de manos,…<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-8307","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8307","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=8307"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/8307\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=8307"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=8307"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=8307"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}