{"id":9234,"date":"2020-04-28T05:13:35","date_gmt":"2020-04-28T08:13:35","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/wiki\/histiocitosis-malignas\/"},"modified":"2020-04-28T05:13:35","modified_gmt":"2020-04-28T08:13:35","slug":"histiocytosis-malignant-2","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/en\/wiki\/histiocitosis-malignas\/","title":{"rendered":"Malignant histiocytosis"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_89 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/histiocitosis-malignas\/#Que-son-maligno-histiocitosis\" >What are malignant histiocytosis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/histiocitosis-malignas\/#Leucemia-monocitica\" >Monocytic leukemia<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/histiocitosis-malignas\/#Leucemia-monocitica-2\" >Monocytic leukemia<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/histiocitosis-malignas\/#Histiocitosis-maligna\" >Malignant histiocytosis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/histiocitosis-malignas\/#Linfoma-histiocitico-verdadero\" >True histiocytic lymphoma<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/doctorhoogstra.com\/en\/wiki\/histiocitosis-malignas\/#%C2%BFCual-es-el-tratamiento\" >Which is the treatment?<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<h2><span class=\"ez-toc-section\" id=\"Que-son-maligno-histiocitosis\"><\/span>What are they <span class=\"term\" data-term-id=\"176\">evil one<\/span> histiocytosis?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Malignant histiocytoses are cancerous conditions in which there is no control <span class=\"term\" data-term-id=\"893\">proliferation<\/span> of the <span class=\"term\" data-term-id=\"857\">histiocyte<\/span> cell. They are also known as class III histocytosis.<\/p>\n<p>Malignant histiocytoses include the following different diseases:<\/p>\n<ul>\n<li>\n<span class=\"term\" data-term-id=\"455\">Monocytic<\/span> <span class=\"term\" data-term-id=\"613\">leukemia<\/span>\n<\/li>\n<li>Evil one <span class=\"term\" data-term-id=\"1346\">histiocytosis<\/span>\n<\/li>\n<li>True <span class=\"term\" data-term-id=\"859\">histiocytic<\/span> <span class=\"term\" data-term-id=\"976\">lymphoma<\/span>\n<\/li>\n<\/ul>\n<p>In all these conditions <span class=\"term\" data-term-id=\"858\">histiocytes<\/span> it spread throughout the body; usually affects the liver, spleen, <span class=\"term\" data-term-id=\"1775\">lymph nodes<\/span> and bone marrow (inside the bone where blood is made). Malignant histiocytoses can also affect other organs, including the skin.<\/p>\n<p>Malignant histiocytoses are diagnosed by blood tests, tests on the bone marrow (bone marrow <span class=\"term\" data-term-id=\"1869\">Aspire<\/span> and <span class=\"term\" data-term-id=\"24\">biopsy<\/span>) and tissue <span class=\"term\" data-term-id=\"1111\">biopsies<\/span>.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Leucemia-monocitica\"><\/span>Monocytic leukemia<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Monocytic leukemia presents with unexpected abnormalities found in blood tests or with <span class=\"term\" data-term-id=\"308\">generalized<\/span> symptoms of fatigue, weight loss, easy bruising, <span class=\"term\" data-term-id=\"805\">recurrent<\/span> infections, lumps on the skin (leukemia <span class=\"term\" data-term-id=\"48\">skin<\/span>) and swollen gums (<span class=\"term\" data-term-id=\"344\">gingival<\/span> <span class=\"term\" data-term-id=\"136\">hyperplasia<\/span>)<\/p>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Leucemia-monocitica-2\"><\/span>Monocytic leukemia<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='bad-histio3__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-9348840-7544101' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/mal-histio3__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-9348840.jpg'>\n<\/div>\n<p class=\"p-small\">Leukemia skin<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='leukaemia3__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildm2xq-9523242-5312368' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/leukaemia3__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDM2XQ-9523242.jpg'>\n<\/div>\n<p class=\"p-small\">Leukemia skin<\/p>\n<\/p><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Histiocitosis-maligna\"><\/span>Malignant histiocytosis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Malignant histiocytosis presents with a sudden onset of generalized symptoms such as <span class=\"term\" data-term-id=\"1176\">fever<\/span>, sweating, weight loss, and enlarged lymph nodes (better sense in the neck, armpits, and groin), and enlarged liver and spleen. Other cells in the blood may decrease resulting in <span class=\"term\" data-term-id=\"598\">anemia<\/span>, low <span class=\"term\" data-term-id=\"616\">platelets<\/span> (cells involved in blood clotting) and low white blood cells (<span class=\"term\" data-term-id=\"145\">infection<\/span>-combat cells).<\/p>\n<p>Half of those affected will have other organs, usually skin, bone, or intestine.<\/p>\n<ul>\n<li>Skin involvement usually takes the form of multiple purple or skin-colored bumps, which can ulcerate.<\/li>\n<li>Bone involvement causes holes in the bones and an increase in calcium levels in the blood. These holes can be seen on x-rays.<\/li>\n<li>Intestinal involvement is often not noticeable until the lumps in the intestine have become very large, causing obstruction or bleeding.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Linfoma-histiocitico-verdadero\"><\/span>True histiocytic lymphoma<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>True histiocytic lymphoma presents with a <span class=\"term\" data-term-id=\"324\">located<\/span> a lump that may be in the lymph glands or another organ; usually the skin, bone or intestine. It remains localized in one area for some time, and can grow quite large in that area. Later, it can spread throughout the body, involving many organs as in malignant histiocytosis.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCual-es-el-tratamiento\"><\/span>Which is the treatment?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Most patients with these cancerous forms of histiocytosis respond to treatment with <span class=\"term\" data-term-id=\"1619\">chemotherapy<\/span> or <span class=\"term\" data-term-id=\"1325\">radiotherapy<\/span>. Malignant histiocytosis progresses very rapidly and treatment should be started as soon as possible. Some people will not respond to treatment and others will die before the condition can be diagnosed and treated.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>Qu\u00e9 son maligno histiocitosis? Las histiocitosis malignas son afecciones cancerosas en las que no hay control proliferaci\u00f3n del histiocito c\u00e9lula. Tambi\u00e9n se conocen como histocitosis de clase III. Las histiocitosis&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-9234","wiki","type-wiki","status-publish","format-standard"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/9234","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/comments?post=9234"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/wiki\/9234\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/media?parent=9234"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/categories?post=9234"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/en\/wp-json\/wp\/v2\/tags?post=9234"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}