{"id":16662,"date":"2020-04-29T05:08:43","date_gmt":"2020-04-29T08:08:43","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/wiki\/patologia-de-la-proteinosis-lipoidea\/"},"modified":"2020-05-03T10:30:15","modified_gmt":"2020-05-03T13:30:15","slug":"patologia-da-lipoid-proteinose","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/pt\/wiki\/patologia-de-la-proteinosis-lipoidea\/","title":{"rendered":"Patologia da proteinose lip\u00f3ide"},"content":{"rendered":"<p><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Conte\u00fado<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Alternar tabela de conte\u00fado\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Alternar<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/patologia-de-la-proteinosis-lipoidea\/#Histologia-de-proteinosis-lipoidea\" >Histologia da proteinose lip\u00f3ide<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/patologia-de-la-proteinosis-lipoidea\/#Patologia-de-la-proteinosis-lipoidea\" >Patologia da proteinose lip\u00f3ide<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/patologia-de-la-proteinosis-lipoidea\/#Estudios-especiales-para-la-proteinosis-lipoidea\" >Estudos especiais para proteinose lip\u00f3ide<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/patologia-de-la-proteinosis-lipoidea\/#Diagnostico-diferencial-de-proteinosis-lipoidea-patologia\" >Diagn\u00f3stico diferencial da patologia da proteinose lip\u00f3ide<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock\">\n<p>A proteinose lip\u00f3ide \u00e9 rara <span class=\"term\" data-term-id=\"828\">autoss\u00f4mico<\/span> doen\u00e7a recessiva causada por <span class=\"term\" data-term-id=\"871\">muta\u00e7\u00f5es<\/span> no <span class=\"term\" data-term-id=\"1692\">a matriz extracelular<\/span> prote\u00edna 1 <span class=\"term\" data-term-id=\"774\">gene<\/span> (ECM1).<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Histologia-de-proteinosis-lipoidea\"><\/span>\n<span class=\"term\" data-term-id=\"128\">Histologia<\/span> proteinose lip\u00f3ide<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Na proteinose lip\u00f3ide, as se\u00e7\u00f5es mostram <span class=\"term\" data-term-id=\"370\">declara\u00e7\u00e3o<\/span> de uma <span class=\"term\" data-term-id=\"449\">eosinof\u00edlico<\/span> <span class=\"term\" data-term-id=\"1606\">homog\u00eaneo<\/span> material no <span class=\"term\" data-term-id=\"61\">derme<\/span> (Figuras 1, 2). O sobrejacente <span class=\"term\" data-term-id=\"85\">epiderme<\/span> talvez <span class=\"term\" data-term-id=\"216\">papilomatoso<\/span> (Figura 1). O material envolve <span class=\"term\" data-term-id=\"953\">vasos sangu\u00edneos<\/span> e <span class=\"term\" data-term-id=\"1608\">anexos<\/span> (Figura 2).<\/p>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Patologia-de-la-proteinosis-lipoidea\"><\/span>Patologia da proteinose lip\u00f3ide<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='figura de lipoide-proteinose-1__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-7475456-8320054' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/lipoid-proteinosis-figure-1__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-7475456.jpg'>\n<\/div>\n<p class=\"p-small\">figura 1<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p>                        <img alt='figura-lip\u00f3ide-proteinose-2__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-9256808-3617162' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/lipoid-proteinosis-figure-2__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-9256808.jpg'>\n<\/div>\n<p class=\"p-small\">Figura 2<\/p>\n<\/p><\/div>\n<\/section>\n<div class=\"clearfix imageLinkBlock\"><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Estudios-especiales-para-la-proteinosis-lipoidea\"><\/span>Estudos especiais para proteinose lip\u00f3ide<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>O material eosinof\u00edlico \u00e9 fortemente positivo para PAS e fracamente positivo ou negativo para vermelho congo e tioflavina-T.<\/p>\n<div id=\"square-placement-country-holder\" class=\"country-dependent advert\">\n<div class=\"box-placement square-placement\">\n<div class=\"advert__frame\">\n<div id=\"dermnet-dermnet-mobbox\">\n<\/div><\/div><\/div><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Diagnostico-diferencial-de-proteinosis-lipoidea-patologia\"><\/span>\n<span class=\"term\" data-term-id=\"813\">Diagn\u00f3stico diferencial<\/span> proteinose lip\u00f3ide <span class=\"term\" data-term-id=\"223\">patologia<\/span><br \/>\n<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Col\u00f3ide <span class=\"term\" data-term-id=\"1651\">milium<\/span> e amiloidose: ambas as condi\u00e7\u00f5es apresentam ac\u00famulo de material eosinof\u00edlico semelhante. Ambos devem ser vermelhos do Congo positivos. A hist\u00f3ria cl\u00ednica pode ser \u00fatil na exclus\u00e3o do col\u00f3ide milium. Estudos imuno-histoqu\u00edmicos para <span class=\"term\" data-term-id=\"155\">borda da cal\u00e7ada<\/span> e outra <span class=\"term\" data-term-id=\"1340\">amil\u00f3ide<\/span>As prote\u00ednas associadas podem ser \u00fateis se houver suspeita de amiloidose.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>La proteinosis lipoidea es rara autos\u00f3mico enfermedad recesiva causada por mutaciones en el la matriz extracelular prote\u00edna 1 gene (ECM1). Histolog\u00eda de proteinosis lipoidea En la proteinosis lipoidea, las secciones&#8230;<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[205],"class_list":["post-16662","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones","tag-patologia"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/wiki\/16662","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/comments?post=16662"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/wiki\/16662\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/media?parent=16662"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/categories?post=16662"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/tags?post=16662"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}