{"id":7958,"date":"2020-04-26T13:54:52","date_gmt":"2020-04-26T16:54:52","guid":{"rendered":"https:\/\/doctorhoogstra.com\/es\/melanoniquia\/"},"modified":"2020-10-30T07:30:44","modified_gmt":"2020-10-30T10:30:44","slug":"melanonychia","status":"publish","type":"wiki","link":"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/","title":{"rendered":"Melanonychia"},"content":{"rendered":"<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-es-melanoniquia\"><\/span>O que \u00e9 <span class=\"term\" data-term-id=\"182\">melanonychia<\/span>?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<section class=\"textBlock\">Melanon\u00edquia \u00e9 a descolora\u00e7\u00e3o marrom ou preta de uma unha. Pode ser <span class=\"term\" data-term-id=\"1769\">difuso<\/span> ou tomar a forma de uma faixa longitudinal.<\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_88 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Conte\u00fado<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Alternar tabela de conte\u00fado\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Alternar<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/#%C2%BFQue-es-melanoniquia\" >O que \u00e9 melanon\u00edquia?<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/#Melanoniquia-longitudinal-benigna\" >Melanon\u00edquia longitudinal benigna<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/#%C2%BFQuien-corre-riesgo-de-melanoniquia\" >Quem est\u00e1 em risco de melanon\u00edquia?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/#%C2%BFQue-causa-la-melanoniquia\" >O que causa a melanon\u00edquia?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/#Hiperplasia-melanocitica\" >hiperplasia melanoc\u00edtica<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/#Hiperplasia-benigna\" >hiperplasia benigna<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/#Hiperplasia-maligna\" >hiperplasia maligna<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/#Activacion-melanocitica\" >Ativa\u00e7\u00e3o de melan\u00f3citos<\/a><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><ul class='ez-toc-list-level-5' ><li class='ez-toc-heading-level-5'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/#Unas-descoloridas\" >unhas descoloridas<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/#%C2%BFCuales-son-las-posibles-complicaciones-de-la-melanoniquia\" >Quais s\u00e3o as poss\u00edveis complica\u00e7\u00f5es da melanon\u00edquia?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/melanoniquia\/#%C2%BFCual-es-el-manejo-de-la-melanoniquia\" >Qual \u00e9 o tratamento da melanon\u00edquia?<\/a><\/li><\/ul><\/nav><\/div>\n\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Melanoniquia-longitudinal-benigna\"><\/span>Melanon\u00edquia longitudinal benigna<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p><img alt='melanonychia-06__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildzd-4474391-2632328-4890213-5033853-3257563-6207187-1079366' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/melanonychia-06__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDZd-4474391-2632328-4890213-5033853-3257563-6207187.jpg' \/><\/p>\n<\/div>\n<div class=\"imageLinkBlock__item__image\">\n<p><img alt='melanonychia-09__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-1336762-2027663-5034260-2995414-9270078-9612251-9994644' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/melanonychia-09__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-1336762-2027663-5034260-2995414-9270078-9612251.jpg' \/><\/p>\n<\/div>\n<div class=\"imageLinkBlock__item__image\">\n<p><img alt='melanonychia-19__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-7105474-1986466-7488064-1961240-3488311-4765091-4102340' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/melanonychia-19__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-7105474-1986466-7488064-1961240-3488311-4765091.jpg' \/><\/p>\n<\/div>\n<\/div>\n<\/section>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQuien-corre-riesgo-de-melanoniquia\"><\/span>Quem est\u00e1 em risco de melanon\u00edquia?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>A melanon\u00edquia pode ocorrer em pessoas de todas as idades, incluindo crian\u00e7as, e afeta igualmente ambos os sexos. \u00c9 mais <span class=\"term\" data-term-id=\"1676\">predominante<\/span> em pessoas com pele de cor, especialmente os tipos de pele V e VI de Fitzpatrick.<\/p>\n<ul>\n<li>Quase todos os povos afro-caribenhos desenvolver\u00e3o <span class=\"term\" data-term-id=\"1521\">pigmenta\u00e7\u00e3o<\/span> do <span class=\"term\" data-term-id=\"193\">unha<\/span> na idade de 50 anos.<\/li>\n<li>A melanon\u00edquia afeta at\u00e9 20% dos japoneses.<\/li>\n<li>Pessoas de pele branca s\u00e3o as menos afetadas.<\/li>\n<\/ul>\n<p>A melanon\u00edquia tamb\u00e9m pode estar associada a <span class=\"term\" data-term-id=\"558\">gen\u00e9tico<\/span> dist\u00farbios, les\u00f5es, medicamentos, defici\u00eancia nutricional, <span class=\"term\" data-term-id=\"1196\">end\u00f3crino<\/span> doen\u00e7a, <span class=\"term\" data-term-id=\"43\">tecido conjuntivo<\/span> doen\u00e7a, <span class=\"term\" data-term-id=\"490\">inflamat\u00f3rio<\/span> doen\u00e7a de pele, um local <span class=\"term\" data-term-id=\"289\">tumor<\/span>ou prego <span class=\"term\" data-term-id=\"145\">infec\u00e7\u00e3o<\/span>.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFQue-causa-la-melanoniquia\"><\/span>O que causa a melanon\u00edquia?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>A placa ungueal \u00e9 dura, <span class=\"term\" data-term-id=\"1603\">transl\u00facido<\/span> estrutura feita de <span class=\"term\" data-term-id=\"155\">borda da cal\u00e7ada<\/span>. Geralmente n\u00e3o \u00e9 <span class=\"term\" data-term-id=\"1520\">pigmentado<\/span>. <span class=\"term\" data-term-id=\"181\">Melan\u00f3citos<\/span> Geralmente permanecem latentes no <span class=\"term\" data-term-id=\"242\">proximal<\/span> matriz ungueal onde a unha se origina. <span class=\"term\" data-term-id=\"180\">Melanina<\/span> \u00e9 depositado na unha em crescimento quando os melan\u00f3citos s\u00e3o ativados, resultando em uma faixa pigmentada, esta \u00e9 a melanon\u00edquia longitudinal.<\/p>\n<p>a <span class=\"term\" data-term-id=\"370\">declara\u00e7\u00e3o<\/span> de melanina na l\u00e2mina ungueal pode resultar de 2 processos:<\/p>\n<ul>\n<li><span class=\"term\" data-term-id=\"136\">Hiperplasia\u00a0<\/span><span class=\"term\" data-term-id=\"785\">Melanoc\u00edtico<\/span><\/li>\n<li>ativa\u00e7\u00e3o dos melan\u00f3citos.<\/li>\n<\/ul>\n<h3><span class=\"ez-toc-section\" id=\"Hiperplasia-melanocitica\"><\/span>hiperplasia melanoc\u00edtica<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>A hiperplasia melanoc\u00edtica refere-se a um aumento do n\u00famero de melan\u00f3citos dentro da matriz ungueal. Isso pode representar um <span class=\"term\" data-term-id=\"22\">benigno<\/span> ou <span class=\"term\" data-term-id=\"176\">maligno<\/span> processo.<\/p>\n<h4 style=\"padding-left: 40px\"><span class=\"ez-toc-section\" id=\"Hiperplasia-benigna\"><\/span>hiperplasia benigna<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p style=\"padding-left: 40px\">Melanoc\u00edtico <span class=\"term\" data-term-id=\"354\">naevi<\/span> eles surgem mais comumente em crian\u00e7as. <span class=\"term\" data-term-id=\"1669\">Histologicamente<\/span> h\u00e1 ninhos de <span class=\"term\" data-term-id=\"353\">nevo<\/span> c\u00e9lulas.<\/p>\n<p style=\"padding-left: 40px\"><span class=\"term\" data-term-id=\"1394\">Lentigines<\/span> eles s\u00e3o mais frequentemente vistos em adultos. Os ninhos est\u00e3o ausentes.<\/p>\n<h4 style=\"padding-left: 40px\"><span class=\"ez-toc-section\" id=\"Hiperplasia-maligna\"><\/span>hiperplasia maligna<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p style=\"padding-left: 40px\"><span class=\"term\" data-term-id=\"1670\">Melanoma<\/span> da unidade ungueal afeta mais comumente os polegares, dedos indicadores e ded\u00f5es dos p\u00e9s.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Activacion-melanocitica\"><\/span>Ativa\u00e7\u00e3o de melan\u00f3citos<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>A ativa\u00e7\u00e3o dos melan\u00f3citos \u00e9 um aumento na produ\u00e7\u00e3o e deposi\u00e7\u00e3o de melanina nas c\u00e9lulas da unha.<span class=\"term\" data-term-id=\"1892\">onic\u00f3citos<\/span>), sem aumento do n\u00famero de melan\u00f3citos. As causas da ativa\u00e7\u00e3o dos melan\u00f3citos est\u00e3o listadas na tabela abaixo.<\/p>\n<p>Melanon\u00edquia associada \u00e0 ativa\u00e7\u00e3o de melan\u00f3citos<\/p>\n<table width=\"490\">\n<tbody>\n<tr>\n<td><span class=\"term\" data-term-id=\"1262\">Fisiol\u00f3gico<\/span> (funcional)<\/td>\n<td>varia\u00e7\u00e3o racial<\/p>\n<p>A gravidez<\/td>\n<\/tr>\n<tr>\n<td><span class=\"term\" data-term-id=\"1365\">Trauma<\/span><\/td>\n<td>Roer unhas, mastigar, quebrar e picar<\/p>\n<p>Atrito devido a deformidade do p\u00e9 ou cal\u00e7ado.<\/td>\n<\/tr>\n<tr>\n<td>doen\u00e7a inflamat\u00f3ria da pele<\/td>\n<td>Psor\u00edase<\/p>\n<p>Acrodermatite Hallopeau<\/p>\n<p>L\u00edquen plano<\/p>\n<p>Amiloidose<\/td>\n<\/tr>\n<tr>\n<td>Les\u00f5es n\u00e3o melanoc\u00edticas.<\/td>\n<td><span class=\"term\" data-term-id=\"1038\">Intraepid\u00e9rmico<\/span> <span class=\"term\" data-term-id=\"32\">carcinoma<\/span><\/p>\n<p><span class=\"term\" data-term-id=\"831\">Basal<\/span> carcinoma celular<\/p>\n<p>Verruga viral<\/td>\n<\/tr>\n<tr>\n<td>Defici\u00eancia nutricional<\/td>\n<td>Defici\u00eancia de vitamina B12 ou folato<\/td>\n<\/tr>\n<tr>\n<td>dist\u00farbios end\u00f3crinos<\/td>\n<td>doen\u00e7a de Addison<\/p>\n<p>Cushing <span class=\"term\" data-term-id=\"350\">s\u00edndrome<\/span><\/p>\n<p><span class=\"term\" data-term-id=\"1642\">Hipertireoidismo<\/span><\/p>\n<p>Acromegalia<\/td>\n<\/tr>\n<tr>\n<td>De outros <span class=\"term\" data-term-id=\"380\">sist\u00eamico<\/span> doen\u00e7a<\/td>\n<td><span class=\"term\" data-term-id=\"1893\">hemossiderose<\/span><\/p>\n<p>Porfiria cut\u00e2nea tardia<\/p>\n<p>Infec\u00e7\u00e3o pelo v\u00edrus da imunodefici\u00eancia humana (<span class=\"term\" data-term-id=\"127\">HIV<\/span>)<\/p>\n<p>L\u00fapus eritematoso sist\u00eamico<\/p>\n<p>Sist\u00eamico <span class=\"term\" data-term-id=\"260\">esclerose<\/span><\/td>\n<\/tr>\n<tr>\n<td>s\u00edndromes<\/td>\n<td>S\u00edndrome de Laugier-Hunziker<\/p>\n<p>S\u00edndrome de Peutz-Jeghers<\/p>\n<p>S\u00edndrome de Touraine<\/td>\n<\/tr>\n<tr>\n<td><span class=\"term\" data-term-id=\"140\">Iatrogenic<\/span><\/td>\n<td>Fototerapia<\/p>\n<p>exposi\u00e7\u00e3o de raios-X; terapia por feixe de el\u00e9trons<\/td>\n<\/tr>\n<tr>\n<td>Medica\u00e7\u00e3o<\/td>\n<td><span class=\"term\" data-term-id=\"1619\">Quimioterapia<\/span> agentes (especialmente <a class=\"wpil_keyword_link\" href=\"https:\/\/doctorhoogstra.com\/pt\/wiki\/hidroxiureia\/\" title=\"hidroxiureia\">hidroxiureia<\/a>, bussulfano, bleomicina, adriamicina, doxorrubicina, ciclofosfamida, 5-fluorouracil)<\/p>\n<p>terapia antimal\u00e1rica<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"term\" data-term-id=\"526\">Pat\u00f3genos<\/span> podem causar melanon\u00edquia irregular, pois estimulam <span class=\"term\" data-term-id=\"148\">inflama\u00e7\u00e3o<\/span> ativa\u00e7\u00e3o dos melan\u00f3citos. Por exemplo:<\/p>\n<ul>\n<li>Gram-negativo <span class=\"term\" data-term-id=\"935\">bact\u00e9rias<\/span> (<em>Proteus mirabilis<\/em>, <em>Klebsiella<\/em>Pseudomonas)<\/li>\n<li>Onicomicose por dermat\u00f3fito (<em>Trichophyton rubrum<\/em>) ou fermento (<em>Candida albicans<\/em>)<\/li>\n<\/ul>\n<p>Agentes externos podem manchar as unhas.<\/p>\n<ul>\n<li><span class=\"term\" data-term-id=\"122\">Cabelo<\/span> Corante<\/li>\n<li>Hena<\/li>\n<li>Esmalte<\/li>\n<li>Pintar.<\/li>\n<\/ul>\n<section class=\"textBlock imageLinkBlockTitle\">\n<h5 class=\"colour--primary\"><span class=\"ez-toc-section\" id=\"Unas-descoloridas\"><\/span>unhas descoloridas<span class=\"ez-toc-section-end\"><\/span><\/h5>\n<\/section>\n<section class=\"imageLinkBlock\">\n<div class=\"flex\">\n<div class=\"imageLinkBlock__item__image\">\n<p><img alt='brown-onicomycosis__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildfd-2318407-8811010-4580247-2741289-4603486-6550294-5646543' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/brown-onychomycosis__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDFd-2318407-8811010-4580247-2741289-4603486-6550294.jpg' \/><\/p>\n<\/div>\n<p class=\"p-small\">Onicomicose pigmentada<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p><img alt='pseudomonas-nail__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisinkildq0xq-5467839-8789888-2668288-2669331-2835570-7978618-4207111' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/pseudomonas-nail__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsInkiLDQ0XQ-5467839-8789888-2668288-2669331-2835570-7978618.jpg' \/><\/p>\n<\/div>\n<p class=\"p-small\">Infec\u00e7\u00e3o das unhas por Pseudomonas<\/p>\n<div class=\"imageLinkBlock__item__image\">\n<p><img alt='unha manchada de ditranol__protectwyjqcm90zwn0il0_focusfillwzi5ncwymjisingildiyxq-6515224-8118263-8520748-8994272-6657461-1109785-3666643' src='https:\/\/doctorhoogstra.com\/wp-content\/uploads\/2020\/04\/dithranol-stained-nail__ProtectWyJQcm90ZWN0Il0_FocusFillWzI5NCwyMjIsIngiLDIyXQ-6515224-8118263-8520748-8994272-6657461-1109785.jpg' \/><\/p>\n<\/div>\n<p class=\"p-small\">Unha manchada de ditranol<\/p>\n<\/div>\n<\/section>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCuales-son-las-posibles-complicaciones-de-la-melanoniquia\"><\/span>Quais s\u00e3o as poss\u00edveis complica\u00e7\u00f5es da melanon\u00edquia?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>As complica\u00e7\u00f5es dependem da causa da melanon\u00edquia.<\/p>\n<ul>\n<li><span class=\"term\" data-term-id=\"622\">Melanoma subungueal:<\/span>\u00a0Pode resultar em <span class=\"term\" data-term-id=\"185\">met\u00e1stase<\/span> e, finalmente, a morte do paciente. O melanoma da matriz ungueal \u00e9 geralmente pior que o melanoma em outros locais.<\/li>\n<li>Trauma, infec\u00e7\u00e3o e doen\u00e7a inflamat\u00f3ria podem causar <span class=\"term\" data-term-id=\"1772\">fissura<\/span> e divis\u00e3o das unhas e unhas feias ou dolorosas <span class=\"term\" data-term-id=\"74\">distrofia<\/span>.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"%C2%BFCual-es-el-manejo-de-la-melanoniquia\"><\/span>Qual \u00e9 o tratamento da melanon\u00edquia?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Quando a melanon\u00edquia \u00e9 atribu\u00edda a uma causa benigna, nenhum tratamento adicional \u00e9 necess\u00e1rio. O manejo do melanoma da unidade ungueal requer <span class=\"term\" data-term-id=\"848\">excis\u00e3o<\/span> do tumor e pode exigir amputa\u00e7\u00e3o de <span class=\"term\" data-term-id=\"1267\">d\u00edgito<\/span>.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>O que \u00e9 melanon\u00edquia? Melanon\u00edquia \u00e9 a descolora\u00e7\u00e3o marrom ou preta de uma unha. Pode ser difuso ou assumir a forma de uma faixa longitudinal. Melanon\u00edquia longitudinal benigna Quem\u2026<\/p>","protected":false},"author":8,"featured_media":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"footnotes":""},"categories":[204],"tags":[],"class_list":["post-7958","wiki","type-wiki","status-publish","format-standard","category-glosario-definiciones"],"_links":{"self":[{"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/wiki\/7958","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/comments?post=7958"}],"version-history":[{"count":0,"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/wiki\/7958\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/media?parent=7958"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/categories?post=7958"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/doctorhoogstra.com\/pt\/wp-json\/wp\/v2\/tags?post=7958"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}