Parabens allergy

What is paraben mixture and where is it found?

The paraben mixture is a mixture of 5 different paraben esters; Benzyl methyl-, ethyl-, propyl-, butyl- and benzyl-parahydroxybenzoate. Parabens are the most commonly used preservatives in current Pharmaceutical preparations are also used in cosmetics, skin care products, medicines, food and industrially in oils, greases, shoe polishes, textiles and glues. Two or more paraben esters are often found in a product, so it is helpful to test the sensitivity of paraben with the paraben mixture, as there is a high incidence of cross reactions between the esters. Benzylparaben is rarely used.

Cosmetic products

• Foundations, powders, correctors.
• Eye makeup (eyeliners, eyeshadow, mascara)
• Facial makeup (blushes)
• Bronze
• Make-up removers
• Lipstick
• Quick-drying nail products

Pharmaceutical / self-hygiene products

• Topical dermatological medications.
• Eye, ear and nose drops
• Rectal and vaginal medications.
• Bandages
• Local anesthetics
• Lotions and moisturizers
• Toothpaste
• Solar filters

• Cleansers and other skin care products.

• Antiperspirants and deodorants
• Soaps and toothpastes

Food products

• Marinated fish products
• Salad dressings
• Mayonnaise
• Mustard
• Spicy sauces
• Processed vegetables
• Frozen dairy products
• Jams and jellies
• Soft drinks and fruit juices
• Baked goods and sweets

What are the reactions to the paraben mixture? allergy?

The sensitivity of the paraben mixture produces a classic allergic contact dermatitis Reactions can sometimes be seen as an outbreak or spread of an existing treated treatment. eruption. Allergic paraben hypersensitivity It is not uncommon, although it is rare in relation to its extended use. Repeated applications of relatively low concentrations of parabens in medicines and cosmetics appear to cause sensitivity. Allergic reactions orally ingested Foods containing parabens are rare.

Am I allergic to the paraben mixture?

The allergy to the paraben mixture is diagnosed from the medical history and by performing patch Testing The patch test is used with a mixture of paraben to 15% in petrolatum.

A self-assessment of a paraben product is possible, but should be done only after first talking to your doctor. This should be done only with products designed to stay on the skin, such as cosmetics (not including eyeliners or mascara) and lotions. Apply a small amount of the product to a small sensitive area of the skin, such as the curve of your arm twice a day for 1 week. Examine the area every day, and if no reaction occurs, you are unlikely to be allergic to it. Still, you should be careful if you intend to use it in large areas as it can still be a irritating.

Products such as shampoos, soaps, and cleansers should not be analyzed in this manner, as they often cause irritating dermatitis.

Treatment of contact dermatitis from exposure to parabens

Anyone diagnosed with an allergy to the paraben mixture should avoid exposure to products containing parabens. Once dermatitis appears on the skin, treatment is like any acute dermatitis/eczema.

• Topical corticosteroids (those that do not contain paraben preservatives)

• Emollients
• High school treatment bacterial infection (Staphylococcus aureus)

What should I do to avoid allergy to the paraben mixture?

Once the sensitivity of paraben is confirmed, try to avoid exposure to any product that contains paraben preservatives. This can be difficult due to its widespread use in many products. Read product labels and avoid products that contain paraben preservatives or any of their alternative names. If you are not sure, ask your pharmacist for advice or a suitable alternative. Other related substances it may also react to include esters of paraaminobenzoic acid (PABA) and paraphenylenediamine.

Alert your doctor and dentist to the fact that you are allergic to parabens. your dermatologist You may have more specific advice, especially if you are very sensitive.

Alternative names / components of parabens

• Methylparaben
• Ethylparaben
• Propylparaben
• Butyl paraben
• Benzyl-parahydroxybenzoate (p-hydroxybenzoate)
• Methyl-parahydroxybenzoate (p-hydroxybenzate)
• Ethyl-parahydroxybenzoate (p-hydroxybenzoate)
• Propyl-parahydroxybenzoate (p-hydroxybenzoate)
• Butyl-parahydroxybenzoate (p-hydroxybenzoate)
• Parahydroxybenzoate (p-hydroxybenzoate)

Avoid all this. At work, request a material safety data sheet to help identify potential sources of exposure.

More information

Parabens, chemical formula and CAS number

• Methyl 4-hydroxybenzoate: C₈H₈OR_3, 99-76-3
• Ethyl 4-hydroxybenzoate: C_{9 9}H₁₀OR_3, 120-47-8
• Propyl-4-hydroxybenzoate: C₁₀H₁₂OR_3, 94-13-3
• Butyl-4-hydroxybenzoate: C₁₁H₁₄OR_3, 94-26-8

Food: E210-219

Cross reactions:

• Paraaminobenzoic acid esters (PABA)
• Paraphenylenediamine

Sensitizer parabens esters

Patch test: 15% paraben mixture in petrolatum (methyl methyl, ethyl, propyl, butyl 3% and benzyl methyl parahydroxybenzoate)

Notes: Topical parabens have recently been reported to have weak estrogenic effects that raise concerns about the breast. Cancer. The investigation is ongoing.

Reference

Book: Fisher's Contact Dermatitis. Ed Rietschel RL, Fowler JF. Lippincott Williams and Wilkins 2001