Linear pororatosis

What is it linear porokeratosis?

Porokeratosis is a group of skin conditions in which there are abnormalities. keratinization. The resulting skin lesions are reddish patches (which may be dry or atrophic) with a well defined ridge-shaped edge called cornoids sheet [one]. In linear porokeratosis, the lesions are arranged in a linear formation. [two].

Who gets linear porokeratosis?

Linear porokeratosis may be present at birth or may not develop into adulthood [2].

What causes linear porokeratosis?

Like other forms of porokeratosis, the cornoid lamina in linear porokeratosis is due to expansion proliferation unusual keratinocytes, which is believed to be due to a genetic mutation. Genetic mutations presenting in mosaic form would explain linearity and often unilateral distribution of injuries [3].

Occasionally there is a family history of linear porokeratosis or other types of porokeratosis, such as disseminated superficial actinic porokeratosis (DSAP), consistent with a genetic predisposition [4].

What are the clinical characteristics of linear porokeratosis?

Linear porokeratosis is presented as numerous grouped lesions, each with its characteristic ridge on its edge and a central groove.

They are arranged in one or more lines along one limb or on one side of the trunk, head and neck, following a dermatomal distribution (i.e. along the pathway of a sensory nerve).

Located linear porokeratosis is unilateral and is often limited to just one limb. the generalized the linear form of porokeratosis is rarer, and the lesions affect various extremities and the trunk [5].

What are the complications of linear porokeratosis?

The main complication of linear porokeratosis is the skin. Cancer, which can develop within linear porokeratosis injury. This can be a basal cell carcinoma or scaly Cell carcinoma and is more likely to occur in older adults [6]. Linear porokeratosis should be monitored by malignancy.

How is linear porokeratosis diagnosed?

Diagnosis of linear porokeratosis is usually made clinically (based on appearance), but sometimes a biopsy Biopsy must include the raised edge of the lesion. the pathology of porokeratosis is very different, but it may be necessary to point out the clinical characteristics for pathologist to find a cornoid lamina within the pathological specimen.

Which is the differential diagnosis of linear porokeratosis?

Other linear injuries that should be considered when evaluating linear porokeratosis include:

• Linear epidermal nevus - this is a hyperpigmented linear birthmark. The initial plane linear epidermal nevus becomes more warty with age. They can appear at birth or within the first years of life.

• Striated lichen - This is a self-limiting form of children's blaschkoid dermatitis Presenting as raised pink or tan dots that come together to form one or more slightly opaque reds scaly Linear bands.

• Porokeratotic eccrine ostial and dermal nevus duct (PEODDN) - This is a warty birthmark that tends to occur on the hands or feet. Individual injuries are discreet papules that are organized in a linear distribution.

Treatment of linear porokeratosis.

There is no known cure for linear porokeratosis, and the treatment is generally disappointing. However, the appearance can be improved with the following measures:

• 5-fluorouracil cream
• Calcipotriol cream
• Oral acitretin or isotretinoin
• Cryotherapy
• Dermabrasion

• Carbon dioxide To be ablation.

Sun protection is very important as exposure to Ultraviolet radiation It can provoke the development of skin cancer within linear porokeratosis.