Malignant proliferative trichilemic cyst

What is a evil one proliferating trichilemmal cyst?

Malignant proliferative tricyclic cyst, also known as malignant proliferative pillar tumor, it is a very rare malignant tumor hair follicle tumor. The cause is unknown, but it appears that a malignant proliferating trichilemmal cyst may have started as a benign tricyclic cyst that then progressed to a proliferating tricyclic cyst before becoming malignant. Some form of trauma, inflammation, and irritation can provide the stimulus for transformation from benign to malignant injury.

To date, fewer than fifty cases of malignant proliferating trichilemmal cysts have been documented.

What are the clinical features of malignant proliferating trichilemmal cysts?

In most cases, the first sign of malignancy is the rapid growth of an ancient nodular lesion of the scalp that may or may not have been diagnosed as a proliferating trichilemic cyst. The malignant cyst can be a reappearance of a previously diagnosed and excised proliferative trichilemic cyst.

Being the malignant counterpart of trichilemmal cyst proliferation, most lesions have been found on the scalp and in women between the ages of 50 and 75. Most lesions are larger than 5 cm, and some grow to 25 cm. These can cause pressure and necrosis in underlying tissues. Regional or distant metastasis It can also be present in advanced cases.

How is a malignant proliferative tricyclic cyst diagnosed?

The diagnosis of a malignant proliferating tricyclic lemur should be based on histological skin findings biopsy. Ideally, the entire lesion should be removed and undergo histological examination.

Specialized staining techniques help differentiate between benign and malignant proliferating tricyclic tumors. Histological evidence of abnormal mitosismarked cellular pleomorphism, infiltrative Growth and aneuploidy may be indicators of malignant transformation. Immunohistochemical studies have also shown that CD34 expression may be an additional feature to distinguish the malignant proliferating tricycilemmal cyst from scaly cell carcinoma.

Malignant proliferative tricyclic carcinoma should be differentiated from other skin tumors such as squamous cell carcinoma, dermoid cysts and cylindroma. Due to its rarity and also inconsistencies in nomenclature and misdiagnosis as squamous cell carcinoma, the true incidence of malignant proliferating trichilemmal cysts is unknown.

What is the treatment of malignant proliferating trichilemmal cysts?

The recommended treatment is complete surgical. excision with a margin of normal tissue. Mohs micrographic surgery can be used to ensure a better margin control. There is currently no consensus on the size of the normal tissue margin. Additional radiotherapy me chemotherapy can be used to treat metastases and for injuries with high metastatic potential.

Patients should be followed closely after surgery for recurrent lesions and any metastases. Malignant proliferating trichilemic cysts have been found to reappear and metastasize in up to 30% of cases.