Mastocytoma

What is a mast cell tumor?

Mastocytoma is the name given to a form of cutaneous mastocytosis in which there is a dermal accumulation of mast cells forming one for you solitary lesions [1].

Who gets a mast cell tumor?

Mast cell tumors are most often diagnosed in a baby 0 to 3 months old.. They are rarely diagnosed in an adult. [2]. Mastocytoma is usually not family.

What Causes a Mast Cell?

TEAM gene, which encodes a transmembrane tyrosine receiver about him mast cells responsible for its growth and function [3].

Mast cell activation causes them to be released histamine and other chemicals that cause located redness, swelling, itching, and sometimes blisters.

What are the clinical features of mast cell tumors?

Typically, one to three mast cell tumors appear in early childhood within the first few months of age. They can occur anywhere on the body.

The typical characteristics of a mast cell are:

• A sign, taint or indurated license plate 1–5 cm in diameter
• The surface may be pitted (orange peel appearance)
• Red, pink, yellow or brown in color.
• Intermittent itching, especially when rubbed
• Rubbing causes injury to urticate (redden and swell) for 15 minutes or so (a positive Darier sign) A blister may occur.

Occasionally localized or generalized Redness can occur when mast cells release chemicals like histamine into the skin.

How is Mast Cell Diagnosed?

Mast cell disease can usually be diagnosed clinically, especially when a positive Darier sign occurs. Dermoscopy is non-specific [4], and the usual patterns seen in melanocytic nevus They are absent. Blood tests are not required.

A skin biopsy reveals a monomorphic mononuclear cell infiltrate it stains positively with a c-KIT and tryptase immunoperoxidase stains [2,3].

Which is the differential diagnosis with mastocytoma?

At first, symptomatic mast cell disease is commonly thought of as a persistent insect bite reaction. If the lesion does not itch, a congenital or early-onset melanocytic nevus may be considered.

Four or more mast cell lesions are best described as maculopapular cutaneous mastocytosisurticaria pigmentosa).

If Darier's sign is positive in adult-onset mast cell tumors, the possibility of more extended cutaneous mastocytosis or systemic Mastocytosis should be considered, especially if there are systemic symptoms such as flushing.

What is the treatment for mast cell tumors?

Scratching or trauma The injury should be minimized to avoid itching, swelling and blisters.

If the mast cell is very itchy, this can often be relieved with an oral antihistamine. Current tacrolimus ointment It has also been reported to reduce symptoms due to a mast cell.

A mastocytoma can be removed in a cosmetically sensitive area. [3], but localized urtication may persist within the scar [2].

What is the result of the mast cell tumor?

Mast cell tumors that arise in childhood usually disappear before puberty. [1].