Mycosis fungoides palmaris and plantaris

What is mycosis fungoides palmaris et plantaris?

Mycosis fungoides palmaris et plantaris is very rare located form of mycosis fungoides, a type of cutaneous T cell lymphoma. While mycosis fungoides affects the hands in approximately 10% of cases, the palmoplantar the variant only affects the hands and feet [1].

Who gets mycosis fungoides palmaris et plantaris?

There are less than 30 reported cases of mycosis fungoides palmaris et plantaris. Although mycosis fungoides palmaris et plantaris can affect all ages, it tends to occur in middle-aged adults [2]. It affects men more often than women. [two].

What causes mycosis fungoides palmaris et plantaris?

The exact cause of mycosis fungoides palmaris et plantaris is unknown. Not only viral, genetic, epigenetics, or the environmental factor has been related to mycosis fungoides [3].

What are the clinical characteristics of mycosis fungoides palmaris et plantaris?

Mycosis fungoides palmaris et plantaris most often resembles a persistent hand eczema and foot eczema [1,2].

• It can affect only the hands, only the feet or both hands and feet.
• Palms and soles are affected more frequently than the upper part of the hands and feet.
• It comes with thickened scaly Red plates, which may or may not cause itching.
• The plates tend to persist or relapse despite treatment.

However, the clinical characteristics of mycosis fungoides palmaris et plantaris can be highly variable. Blisters and pustules, erosions, tumors and ulcers They have all been reported. It rarely affects the nail [2].

What are the complications of mycosis fungoides palmaris et plantaris?

Mycosis fungoides palmaris et plantaris can cause pain, fissureand difficulty using hands and feet.

• Secondary bacterial infection (Staphylococci and / or streptococci) can cause pustules, crust, and pain.

• Progression to a more extensive form of cutaneous T-cell or Sézary lymphoma syndrome It has not been reported, but this is still a potential complication.

How is mycosis fungoides palmaris et plantaris diagnosed?

The clinician may be alerted to an unusual cause of the hands and feet. dermatitis by frequent relapses and resistance to regular treatments. A complete skin examination, including evaluation of lymph nodesas enlarged lymph nodes may suggest more extended lymphoma

The diagnosis of mycosis fungoides palmaris et plantaris is established using tissue. biopsy and evaluation by a dermatopathologist.

the histological The characteristics of mycosis fungoides can be subtle, since early T-cell lymphoma may resemble eczema. Several repeats biopsies it can be necessary

A blood count is needed to ensure there is no associated Sézary syndrome.

Which is the differential diagnosis for mycosis fungoides palmaris and plantaris?

The differential diagnosis of mycosis fungoides palmaris et plantaris includes all forms of dermatitis of the hand. The following should be considered:

• Irritating contact dermatitis: hand eczema caused by exposure to harsh chemicals and irritants; this rarely affects the feet

• Allergic contact dermatitis: a type of eczema that most often affects the hands and is caused by a immune answer to a allergen

• Pompholyx - a form of eczema in which there are clusters of itchy blisters along the sides of the fingers and on the palms, which are often triggered by sweating; Pompholyx can also affect the feet.

• Palmoplantar psoriasis - thickening, climbingand flaking of hands and feet; psoriatic nail dystrophy can be observed

• Palmoplantar pustulosis - a chronic disorder characterized by persistent sensitive groups of pustules on the palms and soles

• Mycosis fungoides: the most common and most common form of cutaneous T-cell lymphoma, which occurs as eczematous patches, badges, nodules, tumors and ulcers, generally in areas protected from the sun, such as the trunk; the eruption it is not limited to the hands and feet.

What is the treatment for mycosis fungoides palmaris et plantaris?

Treatment options for mycosis fungoides palmaris and plantaris depend on the extent of the disease, local experience, and available medications and equipment. The following have been used alone or in combination successfully:

• Current steroids

• Ultraviolet B phototherapy (UVB)

• Photochemotherapy with psoralen and ultraviolet A (PUVA)

• Bexarotene gel (a topical rexinoid)

• Topical Nitrogen Mustard
• Chemotherapy
• Located radiotherapy or electron beam therapy
• Oral retinoids

• Methotrexate

What is the result for mycosis fungoides palmaris et plantaris?

Mycosis fungoides palmaris et plantaris rarely spreads to other tissues and is considered slow growing.

Unlike other lymphomas, the prognosis is generally good. Symptoms can generally be controlled with treatment. However, the treatment is not curative and may reappear after a remission it lasts for many months or years.