Inflammatory linear warty epidermal nevus

What is a inflammatory linear warty epidermal nevus?

An inflammatory linear warty epidermal nevus (ILVEN) is a special type of epidermal nevus. Epidermal naevi are birthmarks due to excessive growth of the epidermis (upper layers of the skin).

What Causes ILVEN?

The abnormality that results in ILVEN arises from a defect in the ectoderm. This is the outer layer of the embryo that gives rise to the epidermis and neural tissue. The defect that causes skin lesions can also cause disorders of other internal organs such as the brain, eyes and skeleton. This is extremely rare with ILVEN.

Who gets ILVEN?

ILVEN can be present at birth, but it usually arises during the first 5 years of life and lasts for months or years. It is somewhat more common in women than in men and occurs in all races.

What are the clinical features of ILVEN?

Like other linear epidermal nevi, ILVEN is characterized by warty lesions that tend to cluster in a linear pattern. The difference is that the lesions are red, swollen, and itchy, sometimes intensely. The surface of the lesions can be seen as eczema (dry, red, streaky) or as psoriasis (red and scaly)

ILVEN most often affects one leg and can spread from the buttock to the foot.

How is ILVEN diagnosed?

ILVEN is diagnosed by a careful history and physical examination. A skin biopsy can be useful and can show the characteristic histological characteristics of ILVEN.

What is the treatment of ILVEN?

There is no curative treatment available for ILVEN. Emollients and low power current Steroids can relieve itching. Emollients or topical calcipotriol can relieve dryness.