Erythrasma pathology

The agent responsible for erythrasma is Corynebacterium minutissimum, a dipheroid. bacterium.

Histology erythrasma

Erythrasma can easily be lost in routine histopathological sections, as inflammatory The response is typically minimal. When a biopsy is done, well-established lesions will reveal a sparse surface perivascular infiltrate of lymphocytes. Normally there are orthokeratosis inside which blue stain organisms Delicate rod and filament form can be found on routine hematoxylin-eosin staining (Figure 1).

Special spots for erythrasma.

The Gram stain of erythrasma shows delicate gram-positive rods and filaments in the cornified layer. They can usually be easily seen on routine hematoxylin-eosin stains (Figure 1)

Differential diagnosis erythrasma pathology

Pityriasis versicolor (sometimes called tinea versicolor) - Malassezia yeasts (formerly known as Pityrosporum) colonize the stratum corneum and they also fail to provoke much of a epidermal reply. Yeast forms are larger than corynebacteria and do not stain with Gram stain.

Normal skin: Causal organisms can be easily overlooked.

Boned keratolysis: may be indistinguishable from erythrasma without clinical correlation.