Conjunctivitis pathology

Conjunctivitis it is inflammation of the conjunctiva Of the eye

Histology conjunctivitis

Low-power view of conjunctivitis histology shows a delicate sample with a slight spongy reaction pattern (figure 1). The conjunctiva epithelium is composed of a stratified scaly epithelium with numerous interspersed goblet cells containing mucin (Figures 2-5). Closer inspection reveals spongiosis of the epithelium with lymphocytic exocytosis (Figures 3, 4). The subepithelial tissue contains telangiectatic vessels and a slight superficial surface. perivascular lymphocytic infiltrate with occasional to numerous plasma cells (figure 5).

Histological variants of conjunctivitis

Allergic conjunctivitis: the presence of numerous eosinophils It is the discriminating characteristic.

Infectious conjunctivitis: typically the presence of numerous neutrophils It should raise concern for a bacterial bacterial conjunctivitis. In histology this cannot be excluded and culture it should be recommended if there are any clinical concerns. Chlamydial conjunctivitis (among others) may have histological characteristics identical to chronic conjunctivitis.

Chronic conjunctivitis: the epithelium is hyperplastic and there are a greater number of plasma cells.

Differential diagnosis conjunctivitis

Woody (pseudomembranous) conjunctivitis: in this variant there are additional deposits of rose amorphous material within the subepithelial tissue, which can mimic amyloid contiguous warehouses with a chronicle inflammatory cellular infiltrate. Clinically there is pseudomembrane formation, which can affect other mucous membrane Surfaces The histologic pseudomembrane generally separates from the underlying epithelium without bleeding.

Giant papillary conjunctivitis: Low power shows a papillomatous projection of the conjunctival epithelium otherwise showing features of chronic conjunctivitis.