Cutaneous lymphadenoma is a follicular tumor which is presented as a small dermal papule. They are considered by many authors as a form of trichoblastoma.
Histology lymphadenoma
In cutaneous lymphadenoma, there is a well circumscribed dermal mass composed of large tumor islands. The around stroma it is fibrotic and is intimately connected with the epithelial islands (figures 1, 2). The islands are infiltrated by impressive populations of lymphocytes (Figures 1–3). There is peripheral palisade surrounding the basaloid follicular cells that form the tumor islands.
Pathology of cutaneous lymphadenoma
Figure 1
Figure 2
figure 3
Special spots for cutaneous lymphadenoma.
Generally none is needed. Lymphocytes have been studied and shown to be a mixture of CD3 positive T cells and CD20 positive B cells.
Differential diagnosis cutaneous lymphadenoma
Infiltrating lymphocytes are highly distinctive for cutaneous lymphadenoma. Without these, the diagnosis is a trichoblastoma.
Basal cell carcinoma will show retraction, irregular growth, and the intimate relationship between epithelium and surrounding stroma seen in benign follicular tumors
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