Glomus tumors are painful. They arise from the neuromyoarterial glomus cells found in the fingers and palms. The normal counterpart from which these tumors arise is the Suquet-Hoyer canal. The clinic injury It is a 1-2 cm reddish-blue solitaire papule in a young adult
Histology of glomus tumors
Glomus tumors are dermal, good circumscribed and consist of small vessels surrounded by glomus cells (Figure 1). Glomus cells have a soft round to oval shape nucleipale eosinophilic cytoplasm and clearly defined cell margins (Figure 2, 3, 4). Mitotic figures and pleomorphism It should not be prominent.
Glomus tumor pathology
Figure 1
Figure 2
figure 3
Figure 4
Figure 5
Special studies of glomus tumors.
Glomus cells are positive for SMA and muscle-specific actin. Myosin can be positive. CD34 and CD31 are positive in endothelial cells; glomus cells are generally negative (Figure 5, CD31 staining).
Differential diagnosis of glomus tumors
Glomuvenous malformation (glomangioma): Vascular The component is more prominent and with dilated vessels. Thrombosis and phlebolith formation may be evident.
Eccrine spiradenoma: distinguished by the presence of two cell populations, positivity for epithelial bookmarks and focal ductal differentiation.
Intradermal nevus: Glomus cells can sometimes resemble naevomelanocytes. Naevus cells are positive with S100 and Melan-A
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