Clioquinol allergy

What is clioquinol and where is it found?

Clioquinol is a quinoline compound that has antibacterial and antifungal properties. Is found in current preparations to treat skin infections as infected eczema, athlete's foot, and other fungal infections. It is also found in preparations combined with hydrocortisone. It can be found in eye and ear preparations.

Other available quinoline compounds include diiodohydroxyquinoline, chlorquinaldol, and chlorhydroxyquinoline.

What are the reactions to clioquinol? allergy?

Sensitivity to clioquinol produces a classic allergic contact. dermatitis reactions Sometimes the condition that was used to treat the topical medicine gets worse or there are no signs of improvement with use. There may be increased irritation, redness, itching, or burning around the infected area.

Am I allergic to clioquinol?

Allergic sensitivity to clioquinol is usually only detected when a skin infection being treated with clioquinol does not respond to treatment or worsens. Clioquinol allergy is diagnosed by performing special allergy tests, i.e. patch Clioquinol tests at 5% in petroleum jelly.

Clioquinol allergy can also mean that you are sensitive to other quinoline compounds.

Clioquinol allergy treatment.

Confirmation of allergy to clioquinol requires prompt removal of the causative agent and then management as for any acute dermatitis / eczema; This may include treatment with topical corticosteroids, emollients and treatment of any secondary bacterial infection (Staphylococcus aureus), etc.

What should I do to avoid a clioquinol allergy?

You should avoid using preparations that contain clioquinol or any of its alternative names. You should also avoid preparations that contain other quinoline compounds. Always alert your doctor to the fact that you have a contact allergy to clioquinol so they can prescribe suitable alternatives if necessary.

If you buy on the counter the products alert your pharmacist to the fact that you have a contact allergy to clioquinol. They should be able to provide you with a suitable alternative.

your dermatologist you may have more specific advice, especially if you are highly sensitive to clioquinol.

Alternative names for clioquinol

Clioquinol is also known by various other names. These include:

• Iodochlorhydroxyquinquin
• Iodochloroxyquinoline
• Iodochlorohydroxyquinoline
• Chlorododoquin
• Vioform

More information

Formula:C_{9 9}H_{5 5}Cl_{5 5}NO

CAS number: 130-26-7

Cross reactions: diiodohydroxyquinoline, chlorquinaldol and hydroxyquinoline.

Sensitizer clioquinol

Patch test: 5% of Clioquinol in Vaseline

Reference

Book: Fisher's Contact Dermatitis. Ed Rietschel RL, Fowler JF. Lippincott Williams and Wilkins 2001