Comedo naevus

What is a comedo nevus?

A naevus comedo is a hair follicle nevus. It is also known as "comedone naevus" and "nevus comedonicus".

A nevus comedo is an unusual type of epidermal nevus or birthmark (a pilosebaceous hamartoma), in which there is a located dilated collection follicles full curb. It is called more exactly follicular keratotic nevus, since there is no truth comedones.

What are the clinical characteristics of the comedo nevus?

Comedo nevus is generally present at birth or develops in early childhood. Men and women are equally likely to be affected. Lesions often grow more rapidly at puberty. They can appear anywhere on the body, but are most commonly found on the face, trunk, neck, and upper extremities.

The injuries appear so closely. grouped slightly elevated papules with central keratinous plugs, making them look like comedones. They can be distributed in a lineardisrupted unilateral or bilateral pattern and sometimes follow Blaschko's lines.

What causes a comedo nevus?

The exact cause of comedo nevus is unknown, but it is believed to be due to cutaneous mosaicism; that is, a line of cells with a genetic error. If this error occurs early in the development of the embryo, the cells can spread to cause multiple comedo. naevi.

Mutations in FGFR2 they have been detected in the nevi of some patients. FGFR2 is the same gene which has turned out to be abnormal in a generalized severe genetic condition, Apert syndromeSo comedo nevus can be a "mosaic" of Apert syndrome (some cells have the abnormal gene and some have the normal gene). Apert syndrome causes craniofacial dysostosis (abnormalities of the bony structure of the skull and face) and other skeletal abnormalities. Patients with Apert syndrome often suffer from severe acne, which also arises within a nevus comedone.

What is comeus navus syndrome?

Comedo navus syndrome is when comedo nevus is associated with other medical conditions. Like other epidermal nevi, the comedo nevus is rarely associated with other abnormalities of the originating cell, the embryonic ectoderm. These may include:

• waterfalls
• Skeletal abnormalities that especially affect the fingers and toes or the spine
• Developmental delay

What is the treatment for comedo nevus?

There is no specific treatment for comedo nevus. The lesions are generally symptomless and treatment for cosmetic purposes is generally sought. Some improvement in injuries can be seen with the use of current tretinoin, salicylic acid, or ammonium lactate lotion.

Surgery and To be Treatment can be used if the injuries are particularly disfiguring.

What are the complications of comedo nevus?

Rarely, at puberty or later, a comedo nevus may develop. inflammatory acne-like lesions within it. These can lead to cysts, recurrent bacterial infections, abscesses and scars. These should be treated with appropriate antibiotics or surgical drainage. Topical and oral acne treatment can improve the appearance.