What is a glomuvenous? malformation?
Glomuvenous malformation is an unusual form of venous malformation, typically diagnosed at birth or later in infancy or childhood. Glomuveous malformation is also known as glomangioma or glomangiomatosis.
Who gets a glomuvenous malformation?
Although the glomuvenous malformation can be sporadic, it can also be family with a autosomal Dominant pattern of inheritance (this is where half of the children of an affected parent inherit the condition). An abnormal chromosome 1p21-p22 has been identified in these families, resulting in the inactivation of a protein called glomulin.
What are the clinical characteristics of glomuvenous malformation?
A glomuvenous malformation presents as a located or segmental collection of soft, pink, red or blue nodules or uniting plates. They can arise anywhere on the skin and can rarely affect mucous membranes you are vascular Lesions are less compressible than other forms of venous malformation.
Injuries tend to increase. extendedthicker and deeper in color with age. Although the nodules start painlessly, they can later become tender to the touch.
How is a glomuvenous malformation diagnosed?
Glomuveous malformation may be suspected due to its clinical appearance; However, biopsy It can also be done. the histology Glomuvenous malformation / glomangioma resembles venous malformation with large, dilated, thin-walled veins in the dermis and subcutaneous tissue. Clusters of alpha-actin positive glomus cells (benign tumor cells in the Soft fabric) are found to line the venous spaces.
How is glomuvenous malformation treated?
Surgical excision Glomuvenous malformation is difficult. Treatment options include To be and sclerotherapy.