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Hair follicle tumors

The pilosebaceous units consist of hair follicle and sebaceous glands are specialized epidermal attached structures that are responsible for hair growth and keeping it healthy.

The hair follicle is made up of the hair bulb at the bottom of the hair follicle and the hair shaft, which emerges from the hair follicle. The sebaceous glands are connected to the hair. follicles and produce tallow, an oily substance that keeps hair and skin hydrated.

Tumors arising from the hair follicle are part of a large and diverse group of neoplasms called adnexal skin tumors. Hair follicle tumors can be benign or evil one growths

Benign hair follicle tumors Malignant hair follicle tumors
  • Basaloid follicular hamartoma
  • Fibrofolliculoma
  • Pilar sheath acanthoma
  • Trichofolliculoma
  • Trichoepithelioma
  • Desmoplastic trichoepithelioma
  • Trichoblastoma
  • Tricoblastic fibroma
  • Trichoadenoma
  • Trichilemmoma
  • Trichilemmal cyst (pillar cyst)
  • Proliferating tricylemmal cyst
  • Pilomatricoma
  • Trichilemmal carcinoma
  • Trichoblastic carcinoma
  • Pilomatrix carcinoma
  • Malignant proliferative trichilemic cyst

For more information, click on the individual hair follicle. tumor types and their pathology.

Tumors involving the sebaceous glands include:

  • sebaceous hyperplasia
  • sebaceous nevus
  • sebaceoma / sebaceous adenoma

  • Sebaceous gland carcinoma.

Management of hair follicle tumors.

Most hair follicle tumors are benign and can be removed with complete local surgery. excision. However, it is important to make a correct diagnosis of the removed tumor in case the patient is at risk of malignancy. Some specific hair follicle tumors are seen in syndromes associated with malignant internal tumors, for example. trichilemomas in Cowden disease. Additionally, many benign tumors have a malignant counterpart that, while rare, can be locally aggressive and have the potential to spread and metastasize.

To achieve an accurate diagnosis of adnexal skin tumors, the pathological evaluation of skin samples should be supported by the following information:

  • Patient's age and sex
  • Location (s) of the injury
  • Tumor growth rate
  • The injury is solitary or multiple.
  • Any inherited associate or systemic diseases

Small or shallow biopsy An injury is not recommended as it can lead to an inaccurate diagnosis. Deep and peripheral surgical resection margins should be performed to ensure complete excision. Patients with malignant tumors should be followed closely for possible regional and distant problems. metastasis.